Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential DL Worthley, M Churchill, JT Compton, Y Tailor, M Rao, Y Si, D Levin, ... Cell 160 (1), 269-284, 2015 | 643 | 2015 |
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease S Vallet, S Mukherjee, N Vaghela, T Hideshima, M Fulciniti, S Pozzi, ... Proceedings of the National Academy of Sciences 107 (11), 5124-5129, 2010 | 305 | 2010 |
Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy V Narasimhan, JA Wright, M Churchill, T Wang, R Rosati, TRM Lannagan, ... Clinical Cancer Research 26 (14), 3662-3670, 2020 | 128 | 2020 |
Bone marrow myeloid cells regulate myeloid-biased hematopoietic stem cells via a histamine-dependent feedback loop X Chen, H Deng, MJ Churchill, LL Luchsinger, X Du, TH Chu, ... Cell stem cell 21 (6), 747-760. e7, 2017 | 87 | 2017 |
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers RZ Yusuf, B Saez, A Sharda, N Van Gastel, VWC Yu, N Baryawno, ... Blood, The Journal of the American Society of Hematology 136 (11), 1303-1316, 2020 | 81 | 2020 |
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes S Niemann, H Kanki, Y Fukui, K Takao, M Fukaya, MN Hynynen, ... European Journal of Neuroscience 26 (6), 1407-1420, 2007 | 60 | 2007 |
DNMT3a mutations in high-risk myelodysplastic syndrome parallel those found in acute myeloid leukemia M Ewalt, NG Galili, M Mumtaz, M Churchill, S Rivera, F Borot, A Raza, ... Blood cancer journal 1 (3), e9-e9, 2011 | 41 | 2011 |
Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer X Chen, Y Takemoto, H Deng, M Middelhoff, RA Friedman, TH Chu, ... Oncoimmunology 6 (3), e1290034, 2017 | 40 | 2017 |
IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer X Chen, MJ Churchill, KK Nagar, YH Tailor, T Chu, BS Rush, Z Jiang, ... Oncotarget 6 (32), 32966, 2015 | 38 | 2015 |
ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia SP Weisberg, MR Smith-Raska, JM Esquilin, J Zhang, TL Arenzana, ... Cell reports 6 (3), 528-540, 2014 | 30 | 2014 |
Motoneuron-specific NR3B gene: No association with ALS and evidence for a common null allele S Niemann, JE Landers, MJ Churchill, B Hosler, P Sapp, WC Speed, ... Neurology 70 (9), 666-676, 2008 | 30 | 2008 |
Bone marrow cells as precursors of the tumor stroma DL Worthley, Y Si, M Quante, M Churchill, S Mukherjee, TC Wang Experimental cell research 319 (11), 1650-1656, 2013 | 29 | 2013 |
Wheel M Churchill, R Brown US Patent App. 29/558,865, 2017 | 25 | 2017 |
Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency S Avagyan, M Churchill, K Yamamoto, JL Crowe, C Li, BJ Lee, T Zheng, ... Blood, The Journal of the American Society of Hematology 124 (10), 1622-1625, 2014 | 19 | 2014 |
Robust p53 stabilization is dispensable for its activation and tumor suppressor function N Kon, M Churchill, H Li, S Mukherjee, JJ Manfredi, W Gu Cancer research 81 (4), 935-944, 2021 | 15 | 2021 |
Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET–rearranged thyroid cancer R Raman, JA Villefranc, TM Ullmann, J Thiesmeyer, V Anelli, J Yao, ... Journal of Experimental Medicine 219 (6), e20210390, 2022 | 8 | 2022 |
personalized medicine: a CLIA-certified high-throughput drug screening platform for ovarian cancer HA Swan, R Rosati, C Bridgwater, MJ Churchill, RM Watt, RC Shaw, ... Cancer Research 78 (13_Supplement), 1619-1619, 2018 | 4 | 2018 |
Predictive value of a CLIA-approved organoid based drug sensitivity test. A Margossian, A Richardson, M Churchill, F Schaub, R Rosati, ... Journal of Clinical Oncology 38 (15_suppl), 3630-3630, 2020 | 3 | 2020 |
Organoid based functional test to predict personalized treatment in cholangiocarcinoma A Margossian, FX Schaub, A Richardson, M Churchill, R Rosati, A Dullea, ... Cancer Research 80 (16_Supplement), 818-818, 2020 | 2 | 2020 |
A novel therapeutic bispecific format based on synthetic orthogonal heterodimers enables T cell activity against Acute myeloid leukemia A Burke, F Borot, X Du, M Churchill, J Ding, AM Grass, P DeSouza, AM Ali, ... Oncogene 42 (1), 26-34, 2023 | 1 | 2023 |