Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ... Journal of Neuroscience 29 (2), 359-370, 2009 | 1215 | 2009 |
Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver M Milanski, AP Arruda, A Coope, LM Ignacio-Souza, CE Nunez, ... Diabetes 61 (6), 1455-1462, 2012 | 248 | 2012 |
Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet R Barbuio, M Milanski, MB Bertolo, MJ Saad, LA Velloso Journal of Endocrinology 194 (3), 539-550, 2007 | 229 | 2007 |
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver DE Cintra, JR Pauli, EP Araújo, JC Moraes, CT de Souza, M Milanski, ... Journal of hepatology 48 (4), 628-637, 2008 | 224 | 2008 |
Low-grade hypothalamic inflammation leads to defective thermogenesis, insulin resistance, and impaired insulin secretion AP Arruda, M Milanski, A Coope, AS Torsoni, E Ropelle, DP Carvalho, ... Endocrinology 152 (4), 1314-1326, 2011 | 221 | 2011 |
AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus A Coope, M Milanski, EP Araújo, M Tambascia, MJA Saad, B Geloneze, ... FEBS letters 582 (10), 1471-1476, 2008 | 200 | 2008 |
Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring RO Benatti, AM Melo, FO Borges, LM Ignacio-Souza, LAP Simino, ... British journal of nutrition 111 (12), 2112-2122, 2014 | 159 | 2014 |
Deletion of tumor necrosis factor-α receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis T Romanatto, EA Roman, AP Arruda, RG Denis, C Solon, M Milanski, ... Journal of Biological Chemistry 284 (52), 36213-36222, 2009 | 158 | 2009 |
Hypothalamic actions of tumor necrosis factor α provide the thermogenic core for the wastage syndrome in cachexia AP Arruda, M Milanski, T Romanatto, C Solon, A Coope, LC Alberici, ... Endocrinology 151 (2), 683-694, 2010 | 98 | 2010 |
Tumor necrosis factor‐α activates signal transduction in hypothalamus and modulates the expression of pro‐inflammatory proteins and orexigenic/anorexigenic neurotransmitters ME Amaral, R Barbuio, M Milanski, T Romanatto, HC Barbosa, W Nadruz, ... Journal of neurochemistry 98 (1), 203-212, 2006 | 80 | 2006 |
Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation AM Melo, RO Benatti, LM Ignacio-Souza, C Okino, AS Torsoni, M Milanski, ... Metabolism 63 (5), 682-692, 2014 | 77 | 2014 |
Defective regulation of the ubiquitin/proteasome system in the hypothalamus of obese male mice LM Ignacio-Souza, B Bombassaro, LB Pascoal, MA Portovedo, DS Razolli, ... Endocrinology 155 (8), 2831-2844, 2014 | 72 | 2014 |
Saturated fatty acids modulate autophagy’s proteins in the hypothalamus M Portovedo, LM Ignacio-Souza, B Bombassaro, A Coope, A Reginato, ... PLoS One 10 (3), e0119850, 2015 | 71 | 2015 |
TNF-α transiently induces endoplasmic reticulum stress and an incomplete unfolded protein response in the hypothalamus RG Denis, AP Arruda, T Romanatto, M Milanski, A Coope, C Solon, ... Neuroscience 170 (4), 1035-1044, 2010 | 70 | 2010 |
Serum levels and mesenteric fat tissue expression of adiponectin and leptin in patients with Crohn's disease VS Rodrigues, M Milanski, JJ Fagundes, AS Torsoni, MLS Ayrizono, ... Clinical & Experimental Immunology 170 (3), 358-364, 2012 | 57 | 2012 |
Lipid overload during gestation and lactation can independently alter lipid homeostasis in offspring and promote metabolic impairment after new challenge to high-fat diet LA de Paula Simino, T de Fante, M Figueiredo Fontana, F Oliveira Borges, ... Nutrition & metabolism 14, 1-15, 2017 | 55 | 2017 |
Beet Stalks and Leaves (Beta vulgaris L.) Protect Against High-Fat Diet-Induced Oxidative Damage in the Liver in Mice IM Lorizola, CPB Furlan, M Portovedo, M Milanski, PB Botelho, ... Nutrients 10 (7), 872, 2018 | 52 | 2018 |
Maternal consumption of high-fat diet in mice alters hypothalamic notch pathway, NPY cell population and food intake in offspring SF Lemes, ACP de Souza, TB Payolla, MD Versutti, AF da Silva Ramalho, ... Neuroscience 371, 1-15, 2018 | 48 | 2018 |
Diet-induced maternal obesity alters insulin signalling in male mice offspring rechallenged with a high-fat diet in adulthood T Fante, LA Simino, A Reginato, TB Payolla, DCG Vitoréli, M Souza, ... PloS one 11 (8), e0160184, 2016 | 45 | 2016 |
Whole transcriptional analysis identifies markers of B, T and plasma cell signaling pathways in the mesenteric adipose tissue associated with Crohn’s disease FAR da Silva, LB Pascoal, I Dotti, ML Setsuko Ayrizono, D Aguilar, ... Journal of translational medicine 18, 1-14, 2020 | 37 | 2020 |