Single-cell phenotyping within transparent intact tissue through whole-body clearing B Yang, JB Treweek, RP Kulkarni, BE Deverman, CK Chen, E Lubeck, ... Cell 158 (4), 945-958, 2014 | 1023 | 2014 |
Single-cell in situ RNA profiling by sequential hybridization E Lubeck, AF Coskun, T Zhiyentayev, M Ahmad, L Cai Nature methods 11 (4), 360-361, 2014 | 886 | 2014 |
In situ transcription profiling of single cells reveals spatial organization of cells in the mouse hippocampus S Shah, E Lubeck, W Zhou, L Cai Neuron 92 (2), 342-357, 2016 | 637 | 2016 |
Single-cell systems biology by super-resolution imaging and combinatorial labeling E Lubeck, L Cai Nature Methods 9 (7), 743-748, 2012 | 520 | 2012 |
Dynamics and spatial genomics of the nascent transcriptome by intron seqFISH S Shah, Y Takei, W Zhou, E Lubeck, J Yun, CHL Eng, N Koulena, ... Cell 174 (2), 363-376. e16, 2018 | 293 | 2018 |
Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing S Shah, E Lubeck, M Schwarzkopf, TF He, A Greenbaum, CH Sohn, ... Development 143 (15), 2862-2867, 2016 | 228 | 2016 |
Propidium Iodide Competes with Ca2+ to Label Pectin in Pollen Tubes and Arabidopsis Root Hairs CM Rounds, E Lubeck, PK Hepler, LJ Winship Plant Physiology 157 (1), 175-187, 2011 | 141 | 2011 |
seqFISH accurately detects transcripts in single cells and reveals robust spatial organization in the hippocampus S Shah, E Lubeck, W Zhou, L Cai Neuron 94 (4), 752-758. e1, 2017 | 131 | 2017 |
Error correction of multiplex imaging analysis by sequential hybridization L Cai, S Shah, E Lubeck, W Zhou US Patent 10,510,435, 2019 | 92 | 2019 |
Multiplex labeling of molecules by sequential hybridization barcoding L Cai, E Lubeck, T Zhiyentayev, A Coskun, TF He, CH Sohn, S Shah US Patent 10,457,980, 2019 | 60 | 2019 |
Multiplex detection of molecular species in cells by super-resolution imaging and combinatorial labeling L Cai, E Lubeck US Patent 10,266,876, 2019 | 39 | 2019 |
The future of cerebral organoids in drug discovery MR Salick, E Lubeck, A Riesselman, A Kaykas Seminars in Cell & Developmental Biology 111, 67-73, 2021 | 25 | 2021 |
Multiplex labeling of molecules by sequential hybridization barcoding using probes with cleavable linkers L Cai, CH Eng, E Lubeck US Patent App. 15/225,820, 2016 | 17 | 2016 |
A pooled cell painting CRISPR screening platform enables de novo inference of gene function by self-supervised deep learning S Sivanandan, B Leitmann, E Lubeck, MM Sultan, P Stanitsas, N Ranu, ... bioRxiv, 2023.08. 13.553051, 2023 | 11 | 2023 |
Editorial note to: In situ transcription profiling of single cells reveals spatial organization of cells in the mouse hippocampus S Shah, E Lubeck, W Zhou, L Cai Neuron 94 (4), 745-746, 2017 | 7 | 2017 |
Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView T Kudo, AM Meireles, R Moncada, Y Chen, P Wu, J Gould, X Hu, ... bioRxiv, 2023.12. 26.573143, 2023 | 2 | 2023 |
Towards in situ Single Cell Systems Biology E Lubeck California Institute of Technology, 2016 | 1 | 2016 |
Machine learning enabled pooled optical screening in human lung cancer cells S Sivanandan, M Salick, B Leitmann, KM Liu, M Sultan, N Ranu, CV Hao, ... NeurIPS 2022 Workshop on Learning Meaningful Representations of Life, 0 | 1 | |
POOLED OPTICAL SCREENING AND TRANSCRIPTIONAL MEASUREMENTS OF CELLS COMPRISING BARCODED GENETIC PERTURBATIONS MR Salick, S Sivanandan, C Hao, E Lubeck, A Kaykas, C Chu US Patent App. 18/113,481, 2024 | | 2024 |
Multiplex labeling of molecules by sequential hybridization barcoding L Cai, E Lubeck, T Zhiyentayev, A Coskun, TF He, CH SOHN, S Shah US Patent App. 17/940,650, 2023 | | 2023 |