| Validation of molecular docking programs for virtual screening against dihydropteroate synthase KE Hevener, W Zhao, DM Ball, K Babaoglu, J Qi, SW White, RE Lee Journal of chemical information and modeling 49 (2), 444-460, 2009 | 539 | 2009 |
| A high-throughput screen for aggregation-based inhibition in a large compound library BY Feng, A Simeonov, A Jadhav, K Babaoglu, J Inglese, BK Shoichet, ... Journal of medicinal chemistry 50 (10), 2385-2390, 2007 | 414 | 2007 |
| Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis K Babaoglu, MA Page, VC Jones, MR McNeil, C Dong, JH Naismith, ... Bioorganic & medicinal chemistry letters 13 (19), 3227-3230, 2003 | 305 | 2003 |
| Structural basis for selectivity and diversity in angiotensin II receptors H Zhang, GW Han, A Batyuk, A Ishchenko, KL White, N Patel, ... Nature 544 (7650), 327-332, 2017 | 226 | 2017 |
| Deconstructing fragment-based inhibitor discovery K Babaoglu, BK Shoichet Nature chemical biology 2 (12), 720-723, 2006 | 211 | 2006 |
| New class of HIV-1 integrase (IN) inhibitors with a dual mode of action M Tsiang, GS Jones, A Niedziela-Majka, E Kan, EB Lansdon, W Huang, ... Journal of Biological Chemistry 287 (25), 21189-21203, 2012 | 199 | 2012 |
| Comprehensive mechanistic analysis of hits from high-throughput and docking screens against β-lactamase K Babaoglu, A Simeonov, JJ Irwin, ME Nelson, B Feng, CJ Thomas, ... Journal of medicinal chemistry 51 (8), 2502-2511, 2008 | 192 | 2008 |
| Discovery of 6-(Fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for … AM Walji, ED Hostetler, H Selnick, Z Zeng, P Miller, I Bennacef, C Salinas, ... Journal of medicinal chemistry 59 (10), 4778-4789, 2016 | 169 | 2016 |
| Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature Structural & Molecular Biology 23 (4), 293-299, 2016 | 144 | 2016 |
| Docking for fragment inhibitors of AmpC β-lactamase DG Teotico, K Babaoglu, GJ Rocklin, RS Ferreira, AM Giannetti, ... Proceedings of the National Academy of Sciences 106 (18), 7455-7460, 2009 | 134 | 2009 |
| Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study RL Mackman, M Sangi, D Sperandio, JP Parrish, E Eisenberg, M Perron, ... Journal of Medicinal Chemistry 58 (4), 1630-1643, 2015 | 131 | 2015 |
| The HIV-1 reverse transcriptase M184I mutation enhances the E138K-associated resistance to rilpivirine and decreases viral fitness R Kulkarni, K Babaoglu, EB Lansdon, L Rimsky, V Van Eygen, G Picchio, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 59 (1), 47-54, 2012 | 103 | 2012 |
| Structural studies of pterin-based inhibitors of dihydropteroate synthase KE Hevener, MK Yun, J Qi, ID Kerr, K Babaoglu, JG Hurdle, K Balakrishna, ... Journal of medicinal chemistry 53 (1), 166-177, 2010 | 96 | 2010 |
| Crystal structure of 7, 8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design K Babaoglu, J Qi, RE Lee, SW White Structure 12 (9), 1705-1717, 2004 | 94 | 2004 |
| Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids as β-lactamase inhibitors O Eidam, C Romagnoli, E Caselli, K Babaoglu, DT Pohlhaus, J Karpiak, ... Journal of medicinal chemistry 53 (21), 7852-7863, 2010 | 91 | 2010 |
| Broad spectrum influenza virus vaccine G Ciaramella, EYC Huang, K Babaoglu, JA Flynn, L Zhang US Patent App. 15/767,609, 2018 | 66 | 2018 |
| Overview of methods and strategies for conducting virtual small molecule screening X Fradera, K Babaoglu Current protocols in chemical biology 9 (3), 196-212, 2017 | 57 | 2017 |
| Affinities between the binding partners of the HIV-1 integrase dimer-lens epithelium-derived growth factor (IN dimer-LEDGF) complex M Tsiang, GS Jones, M Hung, S Mukund, B Han, X Liu, K Babaoglu, ... Journal of biological chemistry 284 (48), 33580-33599, 2009 | 57 | 2009 |
| O-Aryloxycarbonyl Hydroxamates: New β-Lactamase Inhibitors That Cross-Link the Active Site PN Wyrembak, K Babaoglu, RB Pelto, BK Shoichet, RF Pratt Journal of the American Chemical Society 129 (31), 9548-9549, 2007 | 49 | 2007 |
| Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison X He, RCAM van Waardenburg, K Babaoglu, AC Price, KC Nitiss, ... Journal of molecular biology 372 (4), 1070-1081, 2007 | 48 | 2007 |
