| The AlkB family of Fe (II)/α-ketoglutarate-dependent dioxygenases: repairing nucleic acid alkylation damage and beyond BI Fedeles, V Singh, JC Delaney, D Li, JM Essigmann Journal of Biological Chemistry 290 (34), 20734-20742, 2015 | 376 | 2015 |
| Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ... Journal of Biological Chemistry 280 (18), 18265-18273, 2005 | 189 | 2005 |
| Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ... Journal of Biological Chemistry 280 (10), 9547-9554, 2005 | 148 | 2005 |
| Role of tautomerism in RNA biochemistry V Singh, BI Fedeles, JM Essigmann Rna 21 (1), 1-13, 2015 | 138 | 2015 |
| Transition State Structure of 5‘-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli and Its Similarity to Transition State Analogues V Singh, JE Lee, S Núñez, PL Howell, VL Schramm Biochemistry 44 (35), 11647-11659, 2005 | 134 | 2005 |
| Isolation and characterization of Pseudomonas resistant to heavy metals contaminants V Singh, PK Chauhan, R Kanta, T Dhewa, V Kumar International Journal of Pharmaceutical Sciences Review and Research 3 (2 …, 2010 | 118 | 2010 |
| Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity J Sun, V Singh, A Lau, RW Stokes, A Obregón-Henao, IM Orme, D Wong, ... PLoS pathogens 9 (7), e1003499, 2013 | 114 | 2013 |
| A two-step chemical mechanism for ribosome-catalysed peptide bond formation DA Hiller, V Singh, M Zhong, SA Strobel Nature 476 (7359), 236-239, 2011 | 96 | 2011 |
| Structural Rationale for the Affinity of Pico-and Femtomolar Transition State Analogues of Escherichia coli 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase*♦ JE Lee, V Singh, GB Evans, PC Tyler, RH Furneaux, KA Cornell, ... Journal of Biological Chemistry 280 (18), 18274-18282, 2005 | 93 | 2005 |
| Picomolar transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase and X-ray structure with MT-Immucillin-A V Singh, W Shi, GB Evans, PC Tyler, RH Furneaux, SC Almo, ... Biochemistry 43 (1), 9-18, 2004 | 91 | 2004 |
| Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae V Singh, W Shi, SC Almo, GB Evans, RH Furneaux, PC Tyler, GF Painter, ... Biochemistry 45 (43), 12929-12941, 2006 | 90 | 2006 |
| Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer BI Fedeles, BD Freudenthal, E Yau, V Singh, S Chang, D Li, JC Delaney, ... Proceedings of the National Academy of Sciences 112 (33), E4571-E4580, 2015 | 86 | 2015 |
| Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions F Chen, K Bian, Q Tang, BI Fedeles, V Singh, ZT Humulock, ... Chemical research in toxicology 30 (4), 1102-1110, 2017 | 85 | 2017 |
| Picomolar inhibitors as transition-state probes of 5′-methylthioadenosine nucleosidases JA Gutierrez, M Luo, V Singh, L Li, RL Brown, GE Norris, GB Evans, ... ACS chemical biology 2 (11), 725-734, 2007 | 81 | 2007 |
| Second generation transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase GB Evans, RH Furneaux, DH Lenz, GF Painter, VL Schramm, V Singh, ... Journal of medicinal chemistry 48 (14), 4679-4689, 2005 | 77 | 2005 |
| Targeting the polyamine pathway with transition-state analogue inhibitors of 5 ‘-methylthioadenosine phosphorylase GB Evans, RH Furneaux, VL Schramm, V Singh, PC Tyler Journal of medicinal chemistry 47 (12), 3275-3281, 2004 | 65 | 2004 |
| Transition-State Analysis of S. pneumoniae 5‘-Methylthioadenosine Nucleosidase V Singh, VL Schramm Journal of the American Chemical Society 129 (10), 2783-2795, 2007 | 61 | 2007 |
| Transition-state structure of human 5 ‘-methylthioadenosine phosphorylase V Singh, VL Schramm Journal of the American Chemical Society 128 (45), 14691-14696, 2006 | 60 | 2006 |
| Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5, 6-dihydro-2′-deoxycytidine D Li, BI Fedeles, V Singh, CS Peng, KJ Silvestre, AK Simi, JH Simpson, ... Proceedings of the National Academy of Sciences 111 (32), E3252-E3259, 2014 | 59 | 2014 |
| Transition-State Variation in Human, Bovine, and Plasmodium falciparum Adenosine Deaminases M Luo, V Singh, EA Taylor, VL Schramm Journal of the American Chemical Society 129 (25), 8008-8017, 2007 | 43 | 2007 |
