| Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis SP Thayer, MP di Magliano, PW Heiser, CM Nielsen, DJ Roberts, ... Nature 425 (6960), 851-856, 2003 | 1953 | 2003 |
| Hedgehog signalling in cancer formation and maintenance MP di Magliano, M Hebrok Nature reviews cancer 3 (12), 903-911, 2003 | 1077 | 2003 |
| Notochord repression of endodermal Sonic hedgehog permits pancreas development M Hebrok, SK Kim, DA Melton Genes & development 12 (11), 1705-1713, 1998 | 791 | 1998 |
| Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma JL Kopp, G von Figura, E Mayes, FF Liu, CL Dubois, JP Morris, FC Pan, ... Cancer cell 22 (6), 737-750, 2012 | 754 | 2012 |
| KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma JP Morris IV, SC Wang, M Hebrok Nature Reviews Cancer 10 (10), 683-695, 2010 | 716 | 2010 |
| Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells Y Ohi, H Qin, C Hong, L Blouin, JM Polo, T Guo, Z Qi, SL Downey, ... Nature cell biology 13 (5), 541-549, 2011 | 677 | 2011 |
| Controlled induction of human pancreatic progenitors produces functional beta‐like cells in vitro HA Russ, AV Parent, JJ Ringler, TG Hennings, GG Nair, M Shveygert, ... The EMBO journal 34 (13), 1759-1772, 2015 | 619 | 2015 |
| Intercellular signals regulating pancreas development and function SK Kim, M Hebrok Genes & development 15 (2), 111-127, 2001 | 578 | 2001 |
| Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression A Fukuda, SC Wang, JP Morris, AE Folias, A Liou, GE Kim, S Akira, ... Cancer cell 19 (4), 441-455, 2011 | 572 | 2011 |
| Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ... Nature medicine 22 (5), 497-505, 2016 | 565 | 2016 |
| Notochord to endoderm signaling is required for pancreas development SK Kim, M Hebrok, DA Melton Development 124 (21), 4243-4252, 1997 | 516 | 1997 |
| Regulation of pancreas development by hedgehog signaling M Hebrok, SK Kim, B St-Jacques, AP McMahon, DA Melton Development 127 (22), 4905-4913, 2000 | 509 | 2000 |
| GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation O Nolan-Stevaux, J Lau, ML Truitt, GC Chu, M Hebrok, ... Genes & development 23 (1), 24-36, 2009 | 461 | 2009 |
| Wnt signaling regulates pancreatic β cell proliferation IC Rulifson, SK Karnik, PW Heiser, D Ten Berge, H Chen, X Gu, ... Proceedings of the National Academy of Sciences 104 (15), 6247-6252, 2007 | 449 | 2007 |
| β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice JP Morris, DA Cano, S Sekine, SC Wang, M Hebrok The Journal of clinical investigation 120 (2), 508-520, 2010 | 438 | 2010 |
| Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells GG Nair, JS Liu, HA Russ, S Tran, MS Saxton, R Chen, C Juang, M Li, ... Nature cell biology 21 (2), 263-274, 2019 | 401 | 2019 |
| Human islets contain four distinct subtypes of β cells C Dorrell, J Schug, PS Canaday, HA Russ, BD Tarlow, MT Grompe, ... Nature communications 7 (1), 11756, 2016 | 367 | 2016 |
| Hedgehog/Ras interactions regulate early stages of pancreatic cancer MP Di Magliano, S Sekine, A Ermilov, J Ferris, AA Dlugosz, M Hebrok Genes & development 20 (22), 3161-3173, 2006 | 352 | 2006 |
| Liver‐specific loss of β‐catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice S Sekine, BYA Lan, M Bedolli, S Feng, M Hebrok Hepatology 43 (4), 817-825, 2006 | 335 | 2006 |
| How does type 1 diabetes develop? The notion of homicide or β-cell suicide revisited MA Atkinson, JA Bluestone, GS Eisenbarth, M Hebrok, KC Herold, D Accili, ... Diabetes 60 (5), 1370-1379, 2011 | 296 | 2011 |
