| Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... Neuron 84 (6), 1213-1225, 2014 | 584 | 2014 |
| Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 579 | 2018 |
| CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity NJ Kramer, MS Haney, DW Morgens, A Jovičić, J Couthouis, A Li, J Ousey, ... Nature genetics 50 (4), 603-612, 2018 | 226 | 2018 |
| RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats SB Yamada, TF Gendron, T Niccoli, NR Genuth, R Grosely, Y Shi, I Glaria, ... Nature neuroscience 22 (9), 1383-1388, 2019 | 94 | 2019 |
| Notch inhibition allows oncogene-independent generation of iPS cells JK Ichida, J Tcw, LA Williams, AC Carter, Y Shi, MT Moura, M Ziller, ... Nature chemical biology 10 (8), 632-639, 2014 | 76 | 2014 |
| Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ... JCI insight 4 (15), 2019 | 55 | 2019 |
| PIKFYVE inhibition mitigates disease in models of diverse forms of ALS ST Hung, GR Linares, WH Chang, Y Eoh, G Krishnan, S Mendonca, ... Cell 186 (4), 786-802. e28, 2023 | 40 | 2023 |
| Mitigating antagonism between transcription and proliferation allows near-deterministic cellular reprogramming KN Babos, KE Galloway, K Kisler, M Zitting, Y Li, Y Shi, B Quintino, ... Cell stem cell 25 (4), 486-500. e9, 2019 | 40 | 2019 |
| Small molecule inhibition of PIKFYVE kinase rescues gain- and loss-of-function C9ORF72 ALS/FTD disease processes in vivo KA Staats, C Seah, A Sahimi, Y Wang, N Koutsodendris, S Lin, D Kim, ... BioRxiv, 685800, 2019 | 22 | 2019 |
| Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons JK Ichida, KA Staats, BN Davis-Dusenbery, K Clement, KE Galloway, ... Development 145 (22), dev168617, 2018 | 14 | 2018 |
| TREX1 Inactivation Unleashes Cancer Cell STING–Interferon Signaling and Promotes Antitumor Immunity T Tani, H Mathsyaraja, M Campisi, ZH Li, K Haratani, CG Fahey, K Ota, ... Cancer Discovery 14 (5), 752-765, 2024 | 11 | 2024 |
| Antisense proline-arginine RAN dipeptides linked to X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... C9ORF72, 0 | 11 | |
| The C9ORF72 repeat expansion alters neurodevelopment E Hendricks, AM Quihuis, ST Hung, J Chang, N Dorjsuren, B Der, ... Cell reports 42 (8), 2023 | 8 | 2023 |
| More than just content: building community in the graduate classroom MJ Venkatesh, AR Elchert, B Fakoya, F Fernandez, AC Kwong, YJ Liu, ... Nature Biotechnology 39 (9), 1161-1165, 2021 | 7 | 2021 |
| Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma G Tarantino, CA Ricker, A Wang, W Ge, TJ Aprati, AY Huang, S Madha, ... BioRxiv, 2022.12. 11.519808, 2022 | 2 | 2022 |
| Methods to treat neurological diseases J Ichida, S Lin, Y Li, Y Shi US Patent 10,758,545, 2020 | 2 | 2020 |
| SpatialCells: automated profiling of tumor microenvironments with spatially resolved multiplexed single-cell data G Wan, Z Maliga, B Yan, T Vallius, Y Shi, S Khattab, C Chang, AJ Nirmal, ... Briefings in Bioinformatics 25 (3), bbae189, 2024 | 1 | 2024 |
| Identification of kinetic neurodegeneration events in patient-derived cell models. JS Lee, T Cheng, T Onishi, C Huang, H Sasaki, M Jones, Y Shi, M Hattori, ... MOLECULAR BIOLOGY OF THE CELL 29 (26), 45-46, 2018 | | 2018 |
| A machine learning framework for kinetic phenotypic prediction of neurological disease states in patient-derived cell models. M Jones, C Huang, H Sasaki, T Cheng, T Sugawara, Y Shi, J Ichida, ... MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
| Haploinsufficiency for Guanine Exchange Factor Activity Leads to Neurodegeneration in C9ORF72 ALS/FTD Y Shi, S Lin, J Ichida MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Justin IchidaUniversity of Southern California在 usc.edu 的电子邮件经过验证
