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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy S Pankiv, TH Clausen, T Lamark, A Brech, JA Bruun, H Outzen, ... Journal of biological chemistry 282 (33), 24131-24145, 2007 | 4934 | 2007 |
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death G Bjørkøy, T Lamark, A Brech, H Outzen, M Perander, A Øvervatn, ... The Journal of cell biology 171 (4), 603-614, 2005 | 3612 | 2005 |
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 8 (4), 445-544, 2012 | 3138* | 2012 |
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Selective autophagy mediated by autophagic adapter proteins T Johansen, T Lamark autophagy 7 (3), 279-296, 2011 | 1966 | 2011 |
Molecular definitions of autophagy and related processes L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ... The EMBO journal 36 (13), 1811-1836, 2017 | 1557 | 2017 |
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription A Jain, T Lamark, E Sjøttem, KB Larsen, JA Awuh, A Øvervatn, ... Journal of biological chemistry 285 (29), 22576-22591, 2010 | 1441 | 2010 |
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates V Kirkin, T Lamark, YS Sou, G Bjørkøy, JL Nunn, JA Bruun, E Shvets, ... Molecular cell 33 (4), 505-516, 2009 | 1308 | 2009 |
Monitoring autophagic degradation of p62/SQSTM1 G Bjørkøy, T Lamark, S Pankiv, A Øvervatn, A Brech, T Johansen Methods in enzymology 452, 181-197, 2009 | 1286 | 2009 |
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy V Rogov, V Dötsch, T Johansen, V Kirkin Molecular cell 53 (2), 167-178, 2014 | 1072 | 2014 |
The LIR motif–crucial for selective autophagy ÅB Birgisdottir, T Lamark, T Johansen Journal of cell science 126 (15), 3237-3247, 2013 | 911 | 2013 |
Autophagy in major human diseases DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ... The EMBO journal 40 (19), e108863, 2021 | 822 | 2021 |
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport S Pankiv, EA Alemu, A Brech, JA Bruun, T Lamark, A Øvervatn, G Bjørkøy, ... Journal of Cell Biology 188 (2), 253-269, 2010 | 686 | 2010 |
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway YT Zheng, S Shahnazari, A Brech, T Lamark, T Johansen, JH Brumell The Journal of Immunology 183 (9), 5909-5916, 2009 | 663 | 2009 |
TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation M Pilli, J Arko-Mensah, M Ponpuak, E Roberts, S Master, MA Mandell, ... Immunity 37 (2), 223-234, 2012 | 659 | 2012 |
Autophagy in healthy aging and disease Y Aman, T Schmauck-Medina, M Hansen, RI Morimoto, AK Simon, ... Nature aging 1 (8), 634-650, 2021 | 633 | 2021 |
Autophagy mediates degradation of nuclear lamina Z Dou, C Xu, G Donahue, T Shimi, JA Pan, J Zhu, A Ivanov, BC Capell, ... Nature 527 (7576), 105-109, 2015 | 615 | 2015 |
Regulation of selective autophagy: the p62/SQSTM1 paradigm T Lamark, S Svenning, T Johansen Essays in biochemistry 61 (6), 609-624, 2017 | 604 | 2017 |
Selective autophagy: ATG8 family proteins, LIR motifs and cargo receptors T Johansen, T Lamark Journal of molecular biology 432 (1), 80-103, 2020 | 555 | 2020 |