Clades of Adeno-associated viruses are widely disseminated in human tissues G Gao, LH Vandenberghe, MR Alvira, Y Lu, R Calcedo, X Zhou, ... Journal of virology 78 (12), 6381-6388, 2004 | 1345 | 2004 |
In vivo gene editing in dystrophic mouse muscle and muscle stem cells M Tabebordbar, K Zhu, JKW Cheng, WL Chew, JJ Widrick, WX Yan, ... Science 351 (6271), 407-411, 2016 | 1206 | 2016 |
Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses R Calcedo, LH Vandenberghe, G Gao, J Lin, JM Wilson The Journal of infectious diseases 199 (3), 381-390, 2009 | 862 | 2009 |
New recombinant serotypes of AAV vectors G Gao, LH Vandenberghe, JM Wilson Current gene therapy 5 (3), 285-297, 2005 | 611 | 2005 |
Adeno-associated viruses undergo substantial evolution in primates during natural infections G Gao, MR Alvira, S Somanathan, Y Lu, LH Vandenberghe, JJ Rux, ... Proceedings of the National Academy of Sciences 100 (10), 6081-6086, 2003 | 461 | 2003 |
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells G Simmons, JD Reeves, CC Grogan, LH Vandenberghe, F Baribaud, ... Virology 305 (1), 115-123, 2003 | 448 | 2003 |
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale M Lock, M Alvira, LH Vandenberghe, A Samanta, J Toelen, Z Debyser, ... Human gene therapy 21 (10), 1259-1271, 2010 | 400 | 2010 |
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor JM Wilson, G Gao, MR Alvira, LH Vandenberghe US Patent 7,906,111, 2011 | 392 | 2011 |
In silico reconstruction of the viral evolutionary lineage yields a potent gene therapy vector E Zinn, S Pacouret, V Khaychuk, HT Turunen, LS Carvalho, ... Cell reports 12 (6), 1056-1068, 2015 | 350 | 2015 |
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain JM Taymans, LH Vandenberghe, CVD Haute, I Thiry, CM Deroose, ... Human gene therapy 18 (3), 195-206, 2007 | 350 | 2007 |
Therapeutic AAV gene transfer to the nervous system: a clinical reality E Hudry, LH Vandenberghe Neuron 101 (5), 839-862, 2019 | 349 | 2019 |
A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear LD Landegger, B Pan, C Askew, SJ Wassmer, SD Gluck, A Galvin, ... Nature biotechnology 35 (3), 280-284, 2017 | 313 | 2017 |
Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors M Allocca, C Mussolino, M Garcia-Hoyos, D Sanges, C Iodice, M Petrillo, ... Journal of virology 81 (20), 11372-11380, 2007 | 312 | 2007 |
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c B Pan, C Askew, A Galvin, S Heman-Ackah, Y Asai, AA Indzhykulian, ... Nature biotechnology 35 (3), 264-272, 2017 | 279 | 2017 |
Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver E Breous, S Somanathan, LH Vandenberghe, JM Wilson Hepatology 50 (2), 612-621, 2009 | 264 | 2009 |
Progress in gene therapy for neurological disorders M Simonato, J Bennett, NM Boulis, MG Castro, DJ Fink, WF Goins, ... Nature Reviews Neurology 9 (5), 277-291, 2013 | 262 | 2013 |
Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey LH Vandenberghe, P Bell, AM Maguire, CN Cearley, R Xiao, R Calcedo, ... Science translational medicine 3 (88), 88ra54-88ra54, 2011 | 257 | 2011 |
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid LH Vandenberghe, L Wang, S Somanathan, Y Zhi, J Figueredo, ... Nature medicine 12 (8), 967-971, 2006 | 251 | 2006 |
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice CL Bell, LH Vandenberghe, P Bell, MP Limberis, GP Gao, K Van Vliet, ... The Journal of clinical investigation 121 (6), 2427-2435, 2011 | 236 | 2011 |
Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro MP Limberis, LH Vandenberghe, L Zhang, RJ Pickles, JM Wilson Molecular Therapy 17 (2), 294-301, 2009 | 212 | 2009 |