Neurotoxins and their binding areas on voltage-gated sodium channels M Stevens, S Peigneur, J Tytgat Frontiers in pharmacology 2, 14152, 2011 | 301 | 2011 |
Conotoxins targeting nicotinic acetylcholine receptors: an overview EKM Lebbe, S Peigneur, I Wijesekara, J Tytgat Marine drugs 12 (5), 2970-3004, 2014 | 171 | 2014 |
Targeting cannabinoid receptors: current status and prospects of natural products D An, S Peigneur, LA Hendrickx, J Tytgat International journal of molecular sciences 21 (14), 5064, 2020 | 146 | 2020 |
A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties S Peigneur, B Billen, R Derua, E Waelkens, S Debaveye, L Béress, ... Biochemical pharmacology 82 (1), 81-90, 2011 | 130 | 2011 |
A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins S Peigneur, L Béress, C Möller, F Marí, WG Forssmann, J Tytgat The FASEB Journal 26 (12), 5141-5151, 2012 | 100 | 2012 |
Crotamine pharmacology revisited: novel insights based on the inhibition of KV channels S Peigneur, DJB Orts, ARP da Silva, N Oguiura, M Boni-Mitake, ... Molecular pharmacology 82 (1), 90-96, 2012 | 91 | 2012 |
Experimental conversion of a defensin into a neurotoxin: implications for origin of toxic function S Zhu, S Peigneur, B Gao, Y Umetsu, S Ohki, J Tytgat Molecular biology and evolution 31 (3), 546-559, 2014 | 80 | 2014 |
A novel sea anemone peptide that inhibits acid-sensing ion channels AA Rodríguez, E Salceda, AG Garateix, AJ Zaharenko, S Peigneur, ... Peptides 53, 3-12, 2014 | 78 | 2014 |
Molecular diversity of the telson and venom components from Pandinus cavimanus (Scorpionidae Latreille 1802): Transcriptome, venomics and function E Diego‐García, S Peigneur, E Clynen, T Marien, L Czech, L Schoofs, ... Proteomics 12 (2), 313-328, 2012 | 68 | 2012 |
Molecular diversity and functional evolution of scorpion potassium channel toxins S Zhu, S Peigneur, B Gao, L Luo, D Jin, Y Zhao, J Tytgat Molecular & Cellular Proteomics 10 (2), S1-S11, 2011 | 65 | 2011 |
Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels S Zhu, S Peigneur, B Gao, X Lu, C Cao, J Tytgat Molecular & Cellular Proteomics 11 (1), 2012 | 63 | 2012 |
Kunitz-Type Peptide HCRG21 from the Sea Anemone Heteractis crispa Is a Full Antagonist of the TRPV1 Receptor M Monastyrnaya, S Peigneur, E Zelepuga, O Sintsova, I Gladkikh, ... Marine Drugs 14 (12), 229, 2016 | 62 | 2016 |
Variability of potassium channel blockers in Mesobuthus eupeus scorpion venom with focus on Kv1. 1: An integrated transcriptomic and proteomic study AI Kuzmenkov, AA Vassilevski, KS Kudryashova, OV Nekrasova, ... Journal of biological chemistry 290 (19), 12195-12209, 2015 | 60 | 2015 |
Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein M Brams, EA Gay, JC Sáez, A Guskov, R van Elk, RC van der Schors, ... Journal of biological chemistry 286 (6), 4420-4428, 2011 | 60 | 2011 |
Toxins in drug discovery and pharmacology S Peigneur, J Tytgat Toxins 10 (3), 126, 2018 | 59 | 2018 |
MeuTXKβ1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity S Zhu, B Gao, A Aumelas, M del Carmen Rodríguez, H Lanz-Mendoza, ... Biochimica et biophysica acta (BBA)-proteins and proteomics 1804 (4), 872-883, 2010 | 58 | 2010 |
The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella MY Sachkova, SA Singer, J Macrander, AM Reitzel, S Peigneur, J Tytgat, ... Molecular Biology and Evolution 36 (9), 2001-2012, 2019 | 57 | 2019 |
Bcs T x3 is a founder of a novel sea anemone toxin family of potassium channel blocker DJB Orts, Y Moran, CT Cologna, S Peigneur, B Madio, D Praher, ... The FEBS journal 280 (19), 4839-4852, 2013 | 52 | 2013 |
Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor C Petrel, HG Hocking, M Reynaud, G Upert, P Favreau, D Biass, ... Biochemical pharmacology 85 (11), 1663-1671, 2013 | 52 | 2013 |
Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom CT Cologna, S Peigneur, JK Rustiguel, MC Nonato, J Tytgat, EC Arantes The FEBS journal 279 (8), 1495-1504, 2012 | 50 | 2012 |