Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM FA Carvalho, N Barnich, A Sivignon, C Darcha, CHF Chan, CP Stanners, ... Journal of Experimental Medicine 206 (10), 2179-2189, 2009 | 346 | 2009 |
Bacteriophages Targeting Adherent Invasive Escherichia coli Strains as a Promising New Treatment for Crohn’s Disease M Galtier, LD Sordi, A Sivignon, A De Vallée, D Maura, C Neut, ... Journal of Crohn's and Colitis 11 (7), 840-847, 2017 | 185 | 2017 |
Adherent-invasive Escherichia coli Induce Claudin-2 Expression and Barrier Defect in CEABAC10 Mice and Crohn's Disease Patients J Denizot, A Sivignon, F Barreau, C Darcha, CHF Chan, CP Stanners, ... Inflammatory bowel diseases 18 (2), 294-304, 2012 | 105 | 2012 |
Thiazolylaminomannosides as potent antiadhesives of type 1 piliated Escherichia coli isolated from Crohn’s disease patients S Brument, A Sivignon, TI Dumych, N Moreau, G Roos, Y Guerardel, ... Journal of medicinal chemistry 56 (13), 5395-5406, 2013 | 93 | 2013 |
Cyclomodulins in Urosepsis Strains of Escherichia coli D Dubois, J Delmas, A Cady, F Robin, A Sivignon, E Oswald, R Bonnet Journal of clinical microbiology 48 (6), 2122-2129, 2010 | 92 | 2010 |
Saccharomyces cerevisiae CNCM I-3856 Prevents Colitis Induced by AIEC Bacteria in the Transgenic Mouse Model Mimicking Crohn's Disease A Sivignon, A De Vallée, N Barnich, J Denizot, C Darcha, G Pignède, ... Inflammatory bowel diseases 21 (2), 276-286, 2015 | 89 | 2015 |
Development of heptylmannoside-based glycoconjugate antiadhesive compounds against adherent-invasive Escherichia coli bacteria associated with Crohn's disease A Sivignon, X Yan, D Alvarez Dorta, R Bonnet, J Bouckaert, E Fleury, ... MBio 6 (6), 10.1128/mbio. 01298-15, 2015 | 76 | 2015 |
Glycopolymers as Antiadhesives of E. coli Strains Inducing Inflammatory Bowel Diseases X Yan, A Sivignon, N Yamakawa, A Crepet, C Travelet, R Borsali, ... Biomacromolecules 16 (6), 1827-1836, 2015 | 74 | 2015 |
The Antiadhesive Strategy in Crohn′s Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut D Alvarez Dorta, A Sivignon, T Chalopin, TI Dumych, G Roos, RO Bilyy, ... ChemBioChem 17 (10), 936-952, 2016 | 65 | 2016 |
Anti-infectious properties of the probiotic Saccharomyces cerevisiae CNCM I-3856 on enterotoxigenic E. coli (ETEC) strain H10407 C Roussel, A Sivignon, A De Vallee, G Garrait, S Denis, V Tsilia, N Ballet, ... Applied microbiology and biotechnology 102, 6175-6189, 2018 | 52 | 2018 |
Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease T Chalopin, DA Dorta, A Sivignon, M Caudan, TI Dumych, RO Bilyy, ... Organic & Biomolecular Chemistry 14 (16), 3913-3925, 2016 | 51 | 2016 |
Tripartite relationship between gut microbiota, intestinal mucus and dietary fibers: towards preventive strategies against enteric infections T Sauvaitre, L Etienne-Mesmin, A Sivignon, P Mosoni, CM Courtin, ... FEMS Microbiology Reviews 45 (2), fuaa052, 2021 | 42 | 2021 |
The potential of FimH as a novel therapeutic target for the treatment of Crohn’s disease A Sivignon, J Bouckaert, J Bernard, SG Gouin, N Barnich Expert Opinion on Therapeutic Targets 21 (9), 837-847, 2017 | 36 | 2017 |
Ulcerative Colitis-associated E. coli pathobionts potentiate colitis in susceptible hosts H Yang, HC Mirsepasi-Lauridsen, C Struve, JM Allaire, A Sivignon, ... Gut Microbes 12 (1), 1847976, 2020 | 31 | 2020 |
Foodborne Enterotoxigenic Escherichia Coli: From Gut Pathogenesis to new Preventive Strategies Involving Probiotics C Roussel, A Sivignon, TV de Wiele, S Blanquet-Diot Future microbiology 12 (1), 73-93, 2017 | 30 | 2017 |
Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease G Chevalier, A Laveissière, G Desachy, N Barnich, A Sivignon, ... Microbiome 9, 1-16, 2021 | 29 | 2021 |
Inhibition profiles of mono-and polyvalent FimH antagonists against 10 different Escherichia coli strains T Chalopin, Y Brissonnet, A Sivignon, D Deniaud, L Cremet, N Barnich, ... Organic & Biomolecular Chemistry 13 (46), 11369-11375, 2015 | 29 | 2015 |
Oligomannose-Rich Membranes of Dying Intestinal Epithelial Cells Promote Host Colonization by Adherent-Invasive E. coli T Dumych, N Yamakawa, A Sivignon, E Garenaux, S Robakiewicz, ... Frontiers in microbiology 9, 742, 2018 | 23 | 2018 |
Heptylmannose-functionalized cellulose for the binding and specific detection of pathogenic E. coli M Cauwel, A Sivignon, C Bridot, MC Nongbe, D Deniaud, B Roubinet, ... Chemical Communications 55 (68), 10158-10161, 2019 | 20 | 2019 |
Brilliant glyconanocapsules for trapping of bacteria X Yan, A Sivignon, P Alcouffe, B Burdin, S Favre-Bonté, R Bilyy, N Barnich, ... Chemical Communications 51 (67), 13193-13196, 2015 | 19 | 2015 |