Ketamine and ketamine metabolite pharmacology: Insights into therapeutic mechanisms P Zanos, R Moaddel, PJ Morris, LM Riggs, JN Highland, P Georgiou, ... Pharmacological Reviews 70 (3), 621-660, 2018 | 998 | 2018 |
Social defeat stress induces a depression-like phenotype in adolescent male C57BL/6 mice SD Iñiguez, LM Riggs, SJ Nieto, G Dayrit, NN Zamora, KL Shawhan, ... Stress 17 (3), 247-255, 2014 | 296 | 2014 |
Vicarious social defeat stress induces depression-related outcomes in female mice SD Iñiguez, FJ Flores-Ramirez, LM Riggs, JB Alipio, I Garcia-Carachure, ... Biological Psychiatry 83 (1), 9-17, 2018 | 183 | 2018 |
Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice SD Iñiguez, A Aubry, LM Riggs, JB Alipio, RM Zanca, FJ Flores-Ramirez, ... Neurobiology of Stress 5, 54-64, 2016 | 117 | 2016 |
Mechanisms of ketamine and its metabolites as antidepressants EM Hess, LM Riggs, M Michaelides, TD Gould Biochemical Pharmacology, 114892, 2021 | 83 | 2021 |
Drp1 mitochondrial fission in D1 neurons mediates behavioral and cellular plasticity during early cocaine abstinence R Chandra, M Engeln, C Schiefer, MH Patton, JA Martin, CT Werner, ... Neuron 96 (6), 1327-1341. e6, 2017 | 77 | 2017 |
Hydroxynorketamines: Pharmacology and potential therapeutic applications JN Highland, P Zanos, LM Riggs, P Georgiou, SM Clark, PJ Morris, ... Pharmacological Reviews 73 (2), 763-791, 2021 | 67 | 2021 |
Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood SD Iniguez, LF Alcantara, BL Warren, LM Riggs, EM Parise, V Vialou, ... Journal of Neuroscience 34 (3), 1007-1021, 2014 | 63 | 2014 |
Ketamine and the future of rapid-acting antidepressants LM Riggs, TD Gould Annual Review of Clinical Psychology 17, 207-231, 2021 | 61 | 2021 |
Reduced Slc6a15 in nucleus accumbens D2-neurons underlies stress susceptibility R Chandra, TC Francis, H Nam, LM Riggs, M Engeln, S Rudzinskas, ... Journal of Neuroscience 37 (27), 6527-6538, 2017 | 40 | 2017 |
(2R,6R)-hydroxynorketamine rapidly potentiates hippocampal glutamatergic transmission through a synapse-specific presynaptic mechanism LM Riggs, Y Aracava, P Zanos, J Fischell, EX Albuquerque, EFR Pereira, ... Neuropsychopharmacology 45 (2), 426–436, 2020 | 39 | 2020 |
Fluoxetine exposure during adolescence increases preference for cocaine in adulthood SD Iñiguez, LM Riggs, SJ Nieto, KN Wright, NN Zamora, B Cruz, ... Scientific Reports 5, 15009, 2015 | 23 | 2015 |
Hydroxynorketamine pharmacokinetics and antidepressant behavioral effects of (2,6)- and (5,R)-methyl-(2R,6R)-hydroxynorketamines JN Highland, PJ Morris, KM Konrath, LM Riggs, NR Hagen, P Zanos, ... ACS Chemical Neuroscience, 2022 | 14 | 2022 |
(R,S)-ketamine and (2R,6R)-hydroxynorketamine differentially affect memory as a function of dosing frequency LM Riggs, X An, EFR Pereira, TD Gould Translational Psychiatry 11, 1-12, 2021 | 13 | 2021 |
Environmental enrichment mitigates the long-lasting sequelae of perinatal fentanyl exposure in mice JB Alipio*, LM Riggs*, M Plank, A Keller Journal of Neuroscience, 2022 | 11 | 2022 |
(2R,6R)-hydroxynorketamine rapidly potentiates optically-evoked Schaffer collateral synaptic activity LM Riggs, SM Thompson, TD Gould Neuropharmacology, 2022 | 8 | 2022 |
Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder N Hasin, LM Riggs, T Shekhtman, J Ashworth, R Lease, RT Oshone, ... Molecular Psychiatry, 2022 | 7* | 2022 |
cAMP-dependent protein kinase signaling is required for (2R,6R)-hydroxynorketamine to potentiate hippocampal glutamatergic transmission LM Riggs, EFR Pereira, SM Thompson, TD Gould Journal of Neurophysiology 131 (1), 64-74, 2024 | 1 | 2024 |
Synaptic mechanisms underlying the rapid antidepressant properties of the (2R,6R)-hydroxynorketamine ketamine metabolite LM Riggs PhD Dissertation, University of Maryland School of Medicine, Baltimore, MD, 2021 | | 2021 |
Ketamine exposure during adolescence increases sensitivity to reward-related stimuli in adulthood LM Riggs California State University, San Bernardino, CA, 2016 | | 2016 |