Clonal selection in the germinal centre by regulated proliferation and hypermutation AD Gitlin, Z Shulman, MC Nussenzweig Nature 509 (7502), 637-640, 2014 | 642 | 2014 |
A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center TA Schwickert, GD Victora, DR Fooksman, AO Kamphorst, MR Mugnier, ... Journal of Experimental Medicine 208 (6), 1243-1252, 2011 | 488 | 2011 |
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching M Di Virgilio, E Callen, A Yamane, W Zhang, M Jankovic, AD Gitlin, ... Science 339 (6120), 711-715, 2013 | 447 | 2013 |
Dynamic signaling by T follicular helper cells during germinal center B cell selection Z Shulman, AD Gitlin, JS Weinstein, B Lainez, E Esplugues, RA Flavell, ... Science 345 (6200), 1058-1062, 2014 | 416 | 2014 |
T follicular helper cell dynamics in germinal centers Z Shulman, AD Gitlin, S Targ, M Jankovic, G Pasqual, MC Nussenzweig, ... Science 341 (6146), 673-677, 2013 | 384 | 2013 |
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ... Immunity 45 (3), 483-496, 2016 | 378 | 2016 |
Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice A Escolano, JM Steichen, P Dosenovic, DW Kulp, J Golijanin, D Sok, ... Cell 166 (6), 1445-1458. e12, 2016 | 325 | 2016 |
Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice P Dosenovic, L von Boehmer, A Escolano, J Jardine, NT Freund, AD Gitlin, ... Cell 161 (7), 1505-1515, 2015 | 298 | 2015 |
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice JA Horwitz, A Halper-Stromberg, H Mouquet, AD Gitlin, A Tretiakova, ... Proceedings of the National Academy of Sciences 110 (41), 16538-16543, 2013 | 295 | 2013 |
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine C Li, A Lee, L Grigoryan, PS Arunachalam, MKD Scott, M Trisal, ... Nature immunology 23 (4), 543-555, 2022 | 253 | 2022 |
T cell help controls the speed of the cell cycle in germinal center B cells AD Gitlin, CT Mayer, TY Oliveira, Z Shulman, MJK Jones, A Koren, ... Science 349 (6248), 643-646, 2015 | 249 | 2015 |
The microanatomic segregation of selection by apoptosis in the germinal center CT Mayer, A Gazumyan, EE Kara, AD Gitlin, J Golijanin, C Viant, J Pai, ... Science 358 (6360), eaao2602, 2017 | 244 | 2017 |
Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice AT McGuire, MD Gray, P Dosenovic, AD Gitlin, NT Freund, J Petersen, ... Nature communications 7 (1), 10618, 2016 | 190 | 2016 |
Sequencing and cloning of antigen-specific antibodies from mouse memory B cells L Von Boehmer, C Liu, S Ackerman, AD Gitlin, Q Wang, A Gazumyan, ... Nature protocols 11 (10), 1908-1923, 2016 | 179 | 2016 |
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo M Medina-Ramírez, F Garces, A Escolano, P Skog, SW de Taeye, ... Journal of Experimental Medicine 214 (9), 2573-2590, 2017 | 160 | 2017 |
Independent roles of switching and hypermutation in the development and persistence of B lymphocyte memory AD Gitlin, L von Boehmer, A Gazumyan, Z Shulman, TY Oliveira, ... Immunity 44 (4), 769-781, 2016 | 150 | 2016 |
ICAMs support B cell interactions with T follicular helper cells and promote clonal selection I Zaretsky, O Atrakchi, RD Mazor, L Stoler-Barak, A Biram, SW Feigelson, ... Journal of Experimental Medicine 214 (11), 3435-3448, 2017 | 98 | 2017 |
Integration of innate immune signalling by caspase-8 cleavage of N4BP1 AD Gitlin, K Heger, AF Schubert, R Reja, D Yan, VC Pham, E Suto, ... Nature 587 (7833), 275-280, 2020 | 78 | 2020 |
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway EH Kim, MC Woodruff, L Grigoryan, B Maier, SH Lee, P Mandal, ... Elife 9, e52687, 2020 | 63 | 2020 |
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells S Kubicek, JC Gilbert, D Fomina-Yadlin, AD Gitlin, Y Yuan, FF Wagner, ... Proceedings of the National Academy of Sciences 109 (14), 5364-5369, 2012 | 61 | 2012 |