| Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation W Yang, Y Xia, H Ji, Y Zheng, J Liang, W Huang, X Gao, K Aldape, Z Lu Nature 480 (7375), 118-122, 2011 | 933 | 2011 |
| Phosphorylation of β-catenin by AKT promotes β-catenin transcriptional activity D Fang, D Hawke, Y Zheng, Y Xia, J Meisenhelder, H Nika, GB Mills, ... Journal of Biological Chemistry 282 (15), 11221-11229, 2007 | 919 | 2007 |
| Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion Z Lu, S Ghosh, Z Wang, T Hunter Cancer cell 4 (6), 499-515, 2003 | 834 | 2003 |
| ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect W Yang, Y Zheng, Y Xia, H Ji, X Chen, F Guo, CA Lyssiotis, K Aldape, ... Nature cell biology 14 (12), 1295-1304, 2012 | 721 | 2012 |
| PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis W Yang, Y Xia, D Hawke, X Li, J Liang, D Xing, K Aldape, T Hunter, ... Cell 150 (4), 685-696, 2012 | 721 | 2012 |
| ERK1/2 MAP kinases in cell survival and apoptosis Z Lu, S Xu IUBMB life 58 (11), 621-631, 2006 | 707 | 2006 |
| Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor BH Jiang, G Jiang, JZ Zheng, Z Lu, T Hunter, PK Vogt | 706 | 2001 |
| Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase Z Lu, G Jiang, P Blume-Jensen, T Hunter Molecular and cellular biology 21 (12), 4016-4031, 2001 | 425 | 2001 |
| Activation of protein kinase C triggers its ubiquitination and degradation Z Lu, D Liu, A Hornia, W Devonish, M Pagano, DA Foster Molecular and cellular biology 18 (2), 839-845, 1998 | 415 | 1998 |
| The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2 Z Lu, S Xu, C Joazeiro, MH Cobb, T Hunter Molecular cell 9 (5), 945-956, 2002 | 370 | 2002 |
| Involvement of Ral GTPase in v-Src-induced phospholipase D activation H Jiang, JQ Luo, T Urano, P Frankel, Z Lu, DA Foster, LA Feig Nature 378 (6555), 409-412, 1995 | 329 | 1995 |
| Mitochondria-translocated PGK1 functions as a protein kinase to coordinate glycolysis and the TCA cycle in tumorigenesis X Li, Y Jiang, J Meisenhelder, W Yang, DH Hawke, Y Zheng, Y Xia, ... Molecular cell 61 (5), 705-719, 2016 | 316 | 2016 |
| EGF-induced ERK activation promotes CK2-mediated disassociation of α-catenin from β-catenin and transactivation of β-catenin H Ji, J Wang, H Nika, D Hawke, S Keezer, Q Ge, B Fang, X Fang, D Fang, ... Molecular cell 36 (4), 547-559, 2009 | 292 | 2009 |
| Tumor promotion by depleting cells of protein kinase Cδ Z Lu, A Hornia, YW Jiang, Q Zang, S Ohno, DA Foster Molecular and cellular biology 17 (6), 3418-3428, 1997 | 283 | 1997 |
| KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase Y Wang, YR Guo, K Liu, Z Yin, R Liu, Y Xia, L Tan, P Yang, JH Lee, X Li, ... Nature 552 (7684), 273-277, 2017 | 272 | 2017 |
| Regulation of chromatin and gene expression by metabolic enzymes and metabolites X Li, G Egervari, Y Wang, SL Berger, Z Lu Nature reviews Molecular cell biology 19 (9), 563-578, 2018 | 266 | 2018 |
| EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis W Yang, Y Xia, Y Cao, Y Zheng, W Bu, L Zhang, MJ You, MY Koh, G Cote, ... Molecular cell 48 (5), 771-784, 2012 | 233 | 2012 |
| PKM2 regulates chromosome segregation and mitosis progression of tumor cells Y Jiang, X Li, W Yang, DH Hawke, Y Zheng, Y Xia, K Aldape, C Wei, ... Molecular cell 53 (1), 75-87, 2014 | 231 | 2014 |
| Ubiquitylation and proteasomal degradation of the p21Cip1, p27Kip1 and p57Kip2 CDK inhibitors Z Lu, T Hunter Cell cycle 9 (12), 2342-2352, 2010 | 227 | 2010 |
| Regulation and function of pyruvate kinase M2 in cancer W Yang, Z Lu Cancer letters 339 (2), 153-158, 2013 | 211 | 2013 |
