| Modulators of 14-3-3 protein–protein interactions LM Stevers, E Sijbesma, M Botta, C MacKintosh, T Obsil, I Landrieu, ... Journal of medicinal chemistry 61 (9), 3755-3778, 2017 | 255 | 2017 |
| Substituted 2-anilinopyrimidines useful as protein kinase inhibitors PD Davis, DFC Moffat, JM Davis, MC Hutchings US Patent 5,958,935, 1999 | 235 | 1999 |
| Substituted 2-anilinopyrimidines useful as protein kinase inhibitors PD Davis, DFC Moffat, JM Davis, MC Hutchings US Patent 6,235,746, 2001 | 206 | 2001 |
| 5-cyano-2-aminopyrimidine derivatives MJ Batchelor, DFC Moffat, JM Davis, MC Hutchings US Patent 6,579,983, 2003 | 176 | 2003 |
| Stabilization of protein-protein interactions in drug discovery SA Andrei, E Sijbesma, M Hann, J Davis, G O’Mahony, MWD Perry, ... Expert opinion on drug discovery 12 (9), 925-940, 2017 | 156 | 2017 |
| Tetrahydroisoquinoline amide substituted phenyl pyrazoles as selective Bcl-2 inhibitors J Porter, A Payne, B de Candole, D Ford, B Hutchinson, G Trevitt, J Turner, ... Bioorganic & Medicinal Chemistry Letters 19 (1), 230-233, 2009 | 132 | 2009 |
| Formation of zirconocene η2-imine complexes by rearrangement of cyclic iminoacyl complexes. JM Davis, RJ Whitby, A Jaxa-Chamiec Tetrahedron letters 33 (38), 5655-5658, 1992 | 83 | 1992 |
| c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis H Chaudhury, M Zakkar, J Boyle, S Cuhlmann, K Van Der Heiden, ... Arteriosclerosis, thrombosis, and vascular biology 30 (3), 546-553, 2010 | 82 | 2010 |
| 4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation TV Hughes, SL Emanuel, AK Beck, SK Wetter, PJ Connolly, P Karnachi, ... Bioorganic & medicinal chemistry letters 17 (12), 3266-3270, 2007 | 58 | 2007 |
| 4, 5-disubstituted-2-aminopyrimidines JM Davis, DFC Moffat US Patent 6,600,037, 2003 | 46 | 2003 |
| Atropisomeric small molecule Bcl-2 ligands: Determination of bioactive conformation J Porter, A Payne, I Whitcombe, B de Candole, D Ford, R Garlish, A Hold, ... Bioorganic & medicinal chemistry letters 19 (6), 1767-1772, 2009 | 45 | 2009 |
| Fused polycyclic 2-aminopyrimidine derivatives JM Davis, PD Davis, DFC Moffat, MJ Batchelor US Patent 6,057,329, 2000 | 44 | 2000 |
| Fused polycyclic 2-aminopyrimidine derivatives JM Davis, PD Davis, DFC Moffat, MJ Batchelor US Patent 6,599,908, 2003 | 40 | 2003 |
| Synthesis of cyclopentylamines using zirconium chemistry JM Davis, RJ Whitby, A Jaxa-Chamiec Tetrahedron letters 35 (9), 1445-1448, 1994 | 40 | 1994 |
| Pyridine and pyrimidine derivatives JM Davis, BJ Langham, M Naik, DC Brookings, RJ Cubbon, RJ Franklin US Patent 7,323,464, 2008 | 37 | 2008 |
| 5-aminopyrazoles useful as tyrosine kinase inhibitors PD Davis, JM Davis, DFC Moffat US Patent 5,922,741, 1999 | 36 | 1999 |
| Novel nucleotide triphosphates as potent P2Y2 agonists D Brookings, RJ Davenport, J Davis, FCA Galvin, S Lloyd, SR Mack, ... Bioorganic & medicinal chemistry letters 17 (2), 562-565, 2007 | 26 | 2007 |
| Bicyclic oxopyridine and oxopyrimidine derivatives JM Davis, DC Brookings, BJ Langham US Patent 7,176,215, 2007 | 23 | 2007 |
| Scalable Synthesis of the VEGF-R2 Kinase Inhibitor JNJ-17029259 Using Ultrasound-Mediated Addition of MeLi−CeCl3 to a Nitrile M Reuman, S Beish, J Davis, MJ Batchelor, MC Hutchings, DFC Moffat, ... The Journal of Organic Chemistry 73 (3), 1121-1123, 2008 | 22 | 2008 |
| 1-Azadiene complexes of zirconocene. J Davis, R Whitby, A Jaxa-Chamiec Chemical Communications 24, 1743, 1991 | 22 | 1991 |
