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Wael Rabeh
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Peripheral protein quality control removes unfolded CFTR from the plasma membrane
T Okiyoneda, H Barrière, M Bagdány, WM Rabeh, K Du, J Höhfeld, ...
Science 329 (5993), 805-810, 2010
4822010
Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function
WM Rabeh, F Bossard, H Xu, T Okiyoneda, M Bagdany, CM Mulvihill, ...
Cell 148 (1), 150-163, 2012
3342012
In situ proteolysis for protein crystallization and structure determination
A Dong, X Xu, AM Edwards
Nature methods 4 (12), 1019-1021, 2007
2902007
Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD+
W Tempel, WM Rabeh, KL Bogan, P Belenky, M Wojcik, HF Seidle, ...
PLoS biology 5 (10), e263, 2007
1762007
Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway
A Ahner, X Gong, BZ Schmidt, KW Peters, WM Rabeh, PH Thibodeau, ...
Molecular biology of the cell 24 (2), 74-84, 2013
1142013
Structure and mechanism of O-acetylserine sulfhydrylase
WM Rabeh, PF Cook
Journal of Biological Chemistry 279 (26), 26803-26806, 2004
1102004
Crystal structures of human pantothenate kinases: insights into allosteric regulation and mutations linked to a neurodegeneration disorder
BS Hong, G Senisterra, WM Rabeh, M Vedadi, R Leonardi, YM Zhang, ...
Journal of Biological Chemistry 282 (38), 27984-27993, 2007
962007
Catalytic dyad residues His41 and Cys145 impact the catalytic activity and overall conformational fold of the main SARS-CoV-2 protease 3-chymotrypsin-like protease
JC Ferreira, S Fadl, AJ Villanueva, WM Rabeh
Frontiers in chemistry 9, 692168, 2021
892021
Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes
A Chattopadhyay, M Meier, S Ivaninskii, P Burkhard, F Speroni, ...
Biochemistry 46 (28), 8315-8330, 2007
832007
Regulation and cytoprotective role of hexokinase III
E Wyatt, R Wu, W Rabeh, HW Park, M Ghanefar, H Ardehali
PloS one 5 (11), e13823, 2010
782010
The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation
MH Nawaz, JC Ferreira, L Nedyalkova, H Zhu, C Carrasco-López, ...
Bioscience reports 38 (1), BSR20171666, 2018
672018
Hexokinase II–derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cells
AD Woldetsadik, MC Vogel, WM Rabeh, M Magzoub
The FASEB Journal 31 (5), 2168, 2017
652017
Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect
J Colas, G Faure, E Saussereau, S Trudel, WM Rabeh, S Bitam, ...
Human molecular genetics 21 (3), 623-634, 2012
532012
Biochemical and biophysical characterization of the main protease, 3-chymotrypsin-like protease (3CLpro) from the novel coronavirus SARS-CoV 2
JC Ferreira, WM Rabeh
Scientific reports 10 (1), 22200, 2020
412020
Crystallographic education in the 21st century
S Gražulis, AA Sarjeant, P Moeck, J Stone-Sundberg, TJ Snyder, ...
Journal of Applied Crystallography 48 (6), 1964-1975, 2015
392015
Beetle luciferases with naturally red-and blue-shifted emission
C Carrasco-López, JC Ferreira, NM Lui, S Schramm, R Berraud-Pache, ...
Life science alliance 1 (4), 2018
292018
Mechanism of the addition half of the O-acetylserine sulfhydrylase-A reaction
WM Rabeh, SS Alguindigue, PF Cook
Biochemistry 44 (14), 5541-5550, 2005
272005
Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2
JC Ferreira, S Fadl, WM Rabeh
Journal of Biological Chemistry 298 (6), 2022
252022
The elusive crystal structure of the neuraminidase inhibitor Tamiflu (oseltamivir phosphate): molecular details of action
P Naumov, N Yasuda, WM Rabeh, J Bernstein
Chemical Communications 49 (19), 1948-1950, 2013
202013
Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS‐CoV‐2 protease 3CLpro
JC Ferreira, S Fadl, M Ilter, H Pekel, R Rezgui, O Sensoy, WM Rabeh
The FASEB Journal 35 (8), 2021
152021
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