Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing D Heckl, MS Kowalczyk, D Yudovich, R Belizaire, RV Puram, ... Nature biotechnology 32 (9), 941-946, 2014 | 626 | 2014 |
Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6 J Xu, VG Sankaran, M Ni, TF Menne, RV Puram, W Kim, SH Orkin Genes & development 24 (8), 783-798, 2010 | 470 | 2010 |
Core circadian clock genes regulate leukemia stem cells in AML RV Puram, MS Kowalczyk, CG de Boer, RK Schneider, PG Miller, ... Cell 165 (2), 303-316, 2016 | 240 | 2016 |
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling PG Miller, F Al-Shahrour, KA Hartwell, LP Chu, M Järås, RV Puram, ... Cancer cell 24 (1), 45-58, 2013 | 180 | 2013 |
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells KA Hartwell, PG Miller, S Mukherjee, AR Kahn, AL Stewart, DJ Logan, ... Nature chemical biology 9 (12), 840-848, 2013 | 139 | 2013 |
Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia M Järås, PG Miller, LP Chu, RV Puram, EC Fink, RK Schneider, ... Journal of Experimental Medicine 211 (4), 605-612, 2014 | 106 | 2014 |
The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia H Li, BG Mar, H Zhang, RV Puram, F Vazquez, BA Weir, WC Hahn, ... Blood, the Journal of the American Society of Hematology 129 (4), 497-508, 2017 | 78 | 2017 |
Thrombocytopenia and thromboses in myocardial infarction associated with eptifibatide-dependent activating antiplatelet antibodies RV Puram, RM Erdil, BN Weber, EH Knelson, AM Van Beuningen, ... Thrombosis and Haemostasis 120 (07), 1137-1141, 2020 | 5 | 2020 |
Defining and Targeting Transcriptional Pathways in Leukemia Stem Cells RV Puram | | 2014 |
Casein Kinase 1 Alpha Maintains Normal and Leukemic Stem Cells by Regulating p53 Activity M Järås, PG Miller, L Chu, RK Schneider, RV Puram, F Al-Shahrour, ... Blood 120 (21), 209, 2012 | | 2012 |
In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling Peter Miller Graduate Student Brigham and Womens Miller, F Al-Shahrour, ... Blood, The Journal of the American Society of Hematology 118 (21), 758-758, 2011 | | 2011 |