Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors M Ehrlich, S Mozafari, M Glatza, L Starost, S Velychko, AL Hallmann, ... Proceedings of the National Academy of Sciences 114 (11), E2243-E2252, 2017 | 236 | 2017 |
Excluding Oct4 from Yamanaka cocktail unleashes the developmental potential of iPSCs S Velychko, K Adachi, KP Kim, Y Hou, CM MacCarthy, G Wu, HR Schöler Cell Stem Cell 25 (6), 737-753. e4, 2019 | 113 | 2019 |
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2 V Malik, LV Glaser, D Zimmer, S Velychko, M Weng, M Holzner, M Arend, ... Nature communications 10 (1), 3477, 2019 | 67 | 2019 |
Changing POU dimerization preferences converts Oct6 into a pluripotency inducer S Jerabek, CKL Ng, G Wu, MJ Arauzo‐Bravo, KP Kim, D Esch, V Malik, ... EMBO reports 18 (2), 319-333, 2017 | 45 | 2017 |
R-loops coordinate with SOX2 in regulating reprogramming to pluripotency Y Li, Y Song, W Xu, Q Li, X Wang, K Li, J Wang, Z Liu, S Velychko, R Ye, ... Science Advances 6 (24), eaba0777, 2020 | 44 | 2020 |
Reprogramming competence of OCT factors is determined by transactivation domains KP Kim, Y Wu, J Yoon, K Adachi, G Wu, S Velychko, CM MacCarthy, ... Science advances 6 (36), eaaz7364, 2020 | 33 | 2020 |
One-step reprogramming of human fibroblasts into oligodendrocyte-like cells by SOX10, OLIG2, and NKX6. 2 K Chanoumidou, B Hernández-Rodríguez, F Windener, C Thomas, ... Stem Cell Reports 16 (4), 771-783, 2021 | 26 | 2021 |
Functional restoration of gp91phox-oxidase activity by BAC transgenesis and gene targeting in X-linked chronic granulomatous disease iPSCs M Laugsch, M Rostovskaya, S Velychko, C Richter, A Zimmer, B Klink, ... Molecular Therapy 24 (4), 812-822, 2016 | 25 | 2016 |
Fusion of reprogramming factors alters the trajectory of somatic lineage conversion S Velychko, K Kang, SM Kim, TH Kwak, KP Kim, C Park, K Hong, ... Cell Reports 27 (1), 30-39. e4, 2019 | 23 | 2019 |
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells L Xiong, EA Tolen, J Choi, S Velychko, L Caizzi, T Velychko, K Adachi, ... Elife 11, e71533, 2022 | 20 | 2022 |
Directed evolution of an enhanced POU reprogramming factor for cell fate engineering DS Tan, Y Chen, Y Gao, A Bednarz, Y Wei, V Malik, DHH Ho, M Weng, ... Molecular biology and evolution 38 (7), 2854-2868, 2021 | 13 | 2021 |
Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming AG Marthaler, K Adachi, U Tiemann, G Wu, D Sabour, S Velychko, ... Scientific Reports 6 (1), 19415, 2016 | 8 | 2016 |
Highly cooperative chimeric super-SOX induces naive pluripotency across species CM MacCarthy, G Wu, V Malik, Y Menuchin-Lasowski, T Velychko, ... Cell Stem Cell 31 (1), 127-147. e9, 2024 | 6 | 2024 |
Efficient human germ cell specification from stem cells via combinatorial expression of transcription factors C Kramme, MP Smela, B Wolf, PR Fortuna, G Brixi, K Palepu, E Dong, ... | 3 | 2022 |
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids I Rosety, A Zagare, C Saraiva, S Nickels, P Antony, C Almeida, E Glaab, ... npj Parkinson's Disease 9 (1), 166, 2023 | 2 | 2023 |
Enhancing Sox/Oct cooperativity induces higher-grade developmental reset CM MacCarthy, V Malik, G Wu, T Velychko, G Keshet, R Jauch, ... bioRxiv, 2022.09. 23.509242, 2022 | 2 | 2022 |
Redefining SOX2 as a bifunctional mediator of transcription and adjusted translation control N Mittal, M Ataman, H Wang, S Candido, J Lötscher, S Velychko, ... Cancer Research 84 (6_Supplement), 255-255, 2024 | | 2024 |
Sendai virus persistence questions the transient naive reprogramming method for iPSC generation A De Los Angeles, CB Hug, VN Gladyshev, GM Church, S Velychko bioRxiv, 2024 | | 2024 |
Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse embryos HR Schöler, Y Hou, Z Nie, S Velychko, I Bedzhov, S Heising, Q Jiang, ... bioRxiv, 2023.10. 18.562912, 2023 | | 2023 |