Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans B Sönnichsen, LB Koski, A Walsh, P Marschall, B Neumann, M Brehm, ... Nature 434 (7032), 462-469, 2005 | 1071 | 2005 |
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ... Nature genetics 49 (2), 170-174, 2017 | 545 | 2017 |
A functional genomic analysis of cell morphology using RNA interference AA Kiger, B Baum, S Jones, MR Jones, A Coulson, C Echeverri, ... Journal of biology 2, 1-15, 2003 | 498 | 2003 |
Homologous recombination deficiency and platinum-based therapy outcomes in advanced breast cancer EY Zhao, Y Shen, E Pleasance, K Kasaian, S Leelakumari, M Jones, ... Clinical Cancer Research 23 (24), 7521-7530, 2017 | 172 | 2017 |
CancerMine: a literature-mined resource for drivers, oncogenes and tumor suppressors in cancer J Lever, EY Zhao, J Grewal, MR Jones, SJM Jones Nature methods 16 (6), 505-507, 2019 | 153 | 2019 |
NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma MR Jones, LM Williamson, JT Topham, MKC Lee, A Goytain, J Ho, ... Clinical Cancer Research 25 (15), 4674-4681, 2019 | 146 | 2019 |
Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes E Pleasance, E Titmuss, L Williamson, H Kwan, L Culibrk, EY Zhao, ... Nature Cancer 1 (4), 452-468, 2020 | 127 | 2020 |
Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers J Laskin, S Jones, S Aparicio, S Chia, C Ch'ng, R Deyell, P Eirew, A Fok, ... Molecular Case Studies 1 (1), a000570, 2015 | 125 | 2015 |
The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA SA Hammond, RL Warren, BP Vandervalk, E Kucuk, H Khan, EA Gibb, ... Nature communications 8 (1), 1433, 2017 | 111 | 2017 |
Successful targeting of the NRG1 pathway indicates novel treatment strategy for metastatic cancer MR Jones, H Lim, Y Shen, E Pleasance, C Ch'ng, C Reisle, ... Annals of Oncology 28 (12), 3092-3097, 2017 | 108 | 2017 |
NRG1 fusion-driven tumors: biology, detection, and the therapeutic role of afatinib and other ErbB-targeting agents J Laskin, SV Liu, K Tolba, C Heining, RF Schlenk, P Cheema, J Cadranel, ... Annals of Oncology 31 (12), 1693-1703, 2020 | 88 | 2020 |
Application of a neural network whole transcriptome–based pan-cancer method for diagnosis of primary and metastatic cancers JK Grewal, B Tessier-Cloutier, M Jones, S Gakkhar, Y Ma, R Moore, ... JAMA network open 2 (4), e192597-e192597, 2019 | 76 | 2019 |
Assessment of capture and amplicon-based approaches for the development of a targeted next-generation sequencing pipeline to personalize lymphoma management SS Hung, B Meissner, EA Chavez, S Ben-Neriah, D Ennishi, MR Jones, ... The Journal of Molecular Diagnostics 20 (2), 203-214, 2018 | 72 | 2018 |
Whole-genome and transcriptome analysis enhances precision cancer treatment options E Pleasance, A Bohm, LM Williamson, JMT Nelson, Y Shen, M Bonakdar, ... Annals of Oncology 33 (9), 939-949, 2022 | 63 | 2022 |
Whole-genome sequencing in cancer EY Zhao, M Jones, SJM Jones Cold Spring Harbor perspectives in medicine 9 (3), a034579, 2019 | 57 | 2019 |
RNA-mediated interference as a tool for identifying drug targets NJ O’Neil, RL Martin, ML Tomlinson, MR Jones, A Coulson, PE Kuwabara American Journal of Pharmacogenomics 1, 45-53, 2001 | 45 | 2001 |
Response to angiotensin blockade with irbesartan in a patient with metastatic colorectal cancer MR Jones, KA Schrader, Y Shen, E Pleasance, C Ch'Ng, N Dar, S Yip, ... Annals of Oncology 27 (5), 801-806, 2016 | 42 | 2016 |
Therapeutic Potential of Afatinib in NRG1 Fusion‐Driven Solid Tumors: A Case Series J Cadranel, SV Liu, M Duruisseaux, E Branden, Y Goto, BA Weinberg, ... The oncologist 26 (1), 7-16, 2021 | 39 | 2021 |
Text-mining clinically relevant cancer biomarkers for curation into the CIViC database J Lever, MR Jones, AM Danos, K Krysiak, M Bonakdar, JK Grewal, ... Genome medicine 11, 1-16, 2019 | 39 | 2019 |
Base excision repair deficiency signatures implicate germline and somatic MUTYH aberrations in pancreatic ductal adenocarcinoma and breast cancer oncogenesis ML Thibodeau, EY Zhao, C Reisle, C Ch'ng, HL Wong, Y Shen, MR Jones, ... Molecular Case Studies 5 (2), a003681, 2019 | 37 | 2019 |