Role of mitochondrial ROS in the brain: from physiology to neurodegeneration PR Angelova, AY Abramov FEBS letters 592 (5), 692-702, 2018 | 696 | 2018 |
Nrf2 regulates ROS production by mitochondria and NADPH oxidase S Kovac, PR Angelova, KM Holmström, Y Zhang, AT Dinkova-Kostova, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 794-801, 2015 | 595 | 2015 |
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, ... Nature communications 9 (1), 2293, 2018 | 436 | 2018 |
Alpha-synuclein oligomers interact with metal ions to induce oxidative stress and neuronal death in Parkinson's disease E Deas, N Cremades, PR Angelova, MHR Ludtmann, Z Yao, S Chen, ... Antioxidants & redox signaling 24 (7), 376-391, 2016 | 347 | 2016 |
Functional oxygen sensitivity of astrocytes PR Angelova, V Kasymov, I Christie, S Sheikhbahaei, E Turovsky, ... Journal of Neuroscience 35 (29), 10460-10473, 2015 | 282 | 2015 |
Functional role of mitochondrial reactive oxygen species in physiology PR Angelova, AY Abramov Free radical biology and medicine 100, 81-85, 2016 | 245 | 2016 |
Nrf2 affects the efficiency of mitochondrial fatty acid oxidation MHR Ludtmann, PR Angelova, Y Zhang, AY Abramov, ... Biochemical Journal 457 (3), 415-424, 2014 | 244 | 2014 |
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal WY Sun, VA Tyurin, K Mikulska-Ruminska, IH Shrivastava, ... Nature chemical biology 17 (4), 465-476, 2021 | 201 | 2021 |
Ca2+ is a key factor in α-synuclein-induced neurotoxicity PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, ... Journal of cell science 129 (9), 1792-1801, 2016 | 195 | 2016 |
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, ... Cell Death & Differentiation 27 (10), 2781-2796, 2020 | 189 | 2020 |
Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention PR Angelova, N Esteras, AY Abramov Medicinal Research Reviews 41 (2), 770-784, 2021 | 188 | 2021 |
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 182 | 2015 |
Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, ... Cell death & disease 6 (7), e1820-e1820, 2015 | 181 | 2015 |
Monomeric alpha-synuclein exerts a physiological role on brain ATP synthase MHR Ludtmann, PR Angelova, NN Ninkina, S Gandhi, VL Buchman, ... Journal of Neuroscience 36 (41), 10510-10521, 2016 | 174 | 2016 |
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease R Tufi, S Gandhi, IP De Castro, S Lehmann, PR Angelova, D Dinsdale, ... Nature cell biology 16 (2), 157-166, 2014 | 164 | 2014 |
Lipid peroxidation is essential for α‐synuclein‐induced cell death PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, ... Journal of neurochemistry 133 (4), 582-589, 2015 | 148 | 2015 |
Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury HK Siddall, DM Yellon, SB Ong, UA Mukherjee, N Burke, AR Hall, ... PloS one 8 (4), e62400, 2013 | 142 | 2013 |
'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia' R Abeti, MH Parkinson, IP Hargreaves, PR Angelova, C Sandi, MA Pook, ... Cell death & disease 7 (5), e2237-e2237, 2016 | 116 | 2016 |
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, ... Nature neuroscience 25 (9), 1134-1148, 2022 | 108 | 2022 |
Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation PR Angelova, M Barilani, C Lovejoy, M Dossena, M Viganò, A Seresini, ... Redox biology 14, 474-484, 2018 | 108 | 2018 |