Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ... Nature 586 (7827), 113-119, 2020 | 735 | 2020 |
MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ... Cell reports 34 (2), 2021 | 353 | 2021 |
Sequence-resolved detection of pausing by single RNA polymerase molecules KM Herbert, A La Porta, BJ Wong, RA Mooney, KC Neuman, R Landick, ... Cell 125 (6), 1083-1094, 2006 | 327 | 2006 |
Single-molecule studies of RNA polymerase: motoring along KM Herbert, WJ Greenleaf, SM Block Annu. Rev. Biochem. 77, 149-176, 2008 | 246 | 2008 |
Solution structure of an A-tract DNA bend D MacDonald, K Herbert, X Zhang, T Polgruto, P Lu Journal of molecular biology 306 (5), 1081-1098, 2001 | 194 | 2001 |
E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase KM Herbert, J Zhou, RA Mooney, A La Porta, R Landick, SM Block Journal of molecular biology 399 (1), 17-30, 2010 | 136 | 2010 |
Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile KM Herbert, G Pimienta, SJ DeGregorio, A Alexandrov, JA Steitz Cell reports 5 (4), 1070-1081, 2013 | 122 | 2013 |
Pathways and intermediates in forced unfolding of spectrin repeats SM Altmann, RG Grünberg, PF Lenne, J Ylänne, A Raae, K Herbert, ... Structure 10 (8), 1085-1096, 2002 | 99 | 2002 |
A large-scale drug repositioning survey for SARS-CoV-2 antivirals L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, ... BioRxiv, 2020.04. 16.044016, 2020 | 91 | 2020 |
A compound that inhibits the HOP-Hsp90 complex formation and has unique killing effects in breast cancer cell lines G Pimienta, KM Herbert, L Regan Molecular Pharmaceutics, 2011 | 70 | 2011 |
Sensor sensibility—HIV-1 and the innate immune response X Yin, S Langer, Z Zhang, KM Herbert, S Yoh, R König, SK Chanda Cells 9 (1), 254, 2020 | 66 | 2020 |
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses S Langer, C Hammer, K Hopfensperger, L Klein, D Hotter, PD De Jesus, ... Elife 8, e41930, 2019 | 66 | 2019 |
A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting KM Herbert, SK Sarkar, M Mills, HCD De la Herran, KC Neuman, JA Steitz rna 22 (2), 175-183, 2016 | 60 | 2016 |
Noncanonical function of DGCR8 controls mESC exit from pluripotency D Cirera-Salinas, J Yu, M Bodak, RP Ngondo, KM Herbert, C Ciaudo Journal of Cell Biology 216 (2), 355-366, 2017 | 48 | 2017 |
A tale of two RNAs during viral infection: how viruses antagonize mRNAs and small non-coding RNAs in the host cell KM Herbert, A Nag Viruses 8 (6), 154, 2016 | 29 | 2016 |
Consideration of Epstein-Barr virus-encoded noncoding RNAs EBER1 and EBER2 as a functional backup of viral oncoprotein latent membrane protein 1 KM Herbert, G Pimienta MBio 7 (1), 10.1128/mbio. 01926-15, 2016 | 21 | 2016 |
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells A Rodriguez-Frandsen, L Martin-Sancho, AP Gounder, MW Chang, ... Journal of virology 94 (4), 10.1128/jvi. 01410-19, 2020 | 6 | 2020 |
Molecule by molecule, the physics and chemistry of life: SMB 2007 SM Block, MH Larson, WJ Greenleaf, KM Herbert, NR Guydosh, ... Nature chemical biology 3 (4), 193-197, 2007 | 6 | 2007 |
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells (preprint) X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ... | | 2020 |
Sequence Dependent Pausing by RNA Polymerase: A Single Molecule Optical Trapping Study KM Herbert Stanford University, 2008 | | 2008 |