Interleukin-10 determines viral clearance or persistence in vivo DG Brooks, MJ Trifilo, KH Edelmann, L Teyton, DB McGavern, ... Nature medicine 12 (11), 1301-1309, 2006 | 1185 | 2006 |
Blockade of chronic type I interferon signaling to control persistent LCMV infection EB Wilson, DH Yamada, H Elsaesser, J Herskovitz, J Deng, G Cheng, ... Science 340 (6129), 202-207, 2013 | 819 | 2013 |
IL-21 is required to control chronic viral infection H Elsaesser, K Sauer, DG Brooks Science 324 (5934), 1569-1572, 2009 | 693 | 2009 |
Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity Y Kidani, H Elsaesser, MB Hock, L Vergnes, KJ Williams, JP Argus, ... Nature immunology 14 (5), 489-499, 2013 | 495 | 2013 |
Type I interferon in chronic virus infection and cancer LM Snell, TL McGaha, DG Brooks Trends in immunology 38 (8), 542-557, 2017 | 413 | 2017 |
Limiting cholesterol biosynthetic flux spontaneously engages type I IFN signaling AG York, KJ Williams, JP Argus, QD Zhou, G Brar, L Vergnes, EE Gray, ... Cell 163 (7), 1716-1729, 2015 | 391 | 2015 |
Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells LM Fahey, EB Wilson, H Elsaesser, CD Fistonich, DB McGavern, ... Journal of Experimental Medicine 208 (5), 987-999, 2011 | 387 | 2011 |
Recirculating intestinal IgA-producing cells regulate neuroinflammation via IL-10 OL Rojas, AK Pröbstel, EA Porfilio, AA Wang, M Charabati, T Sun, ... Cell 176 (3), 610-624. e18, 2019 | 349 | 2019 |
Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection DG Brooks, L Teyton, MBA Oldstone, DB McGavern Journal of virology 79 (16), 10514-10527, 2005 | 311 | 2005 |
Effects of prostratin on T-cell activation and human immunodeficiency virus latency YD Korin, DG Brooks, S Brown, A Korotzer, JA Zack Journal of virology 76 (16), 8118-8123, 2002 | 288 | 2002 |
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection DG Brooks, SJ Ha, H Elsaesser, AH Sharpe, GJ Freeman, MBA Oldstone Proceedings of the National Academy of Sciences 105 (51), 20428-20433, 2008 | 265 | 2008 |
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 263 | 2022 |
Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype DD Scripture-Adams, DG Brooks, YD Korin, JA Zack Journal of virology 76 (24), 13077-13082, 2002 | 241 | 2002 |
Molecular characterization, reactivation, and depletion of latent HIV DG Brooks, DH Hamer, PA Arlen, L Gao, G Bristol, CMR Kitchen, ... Immunity 19 (3), 413-423, 2003 | 240 | 2003 |
Generation of HIV latency during thymopoiesis DG Brooks, SG Kitchen, CMR Kitchen, DD Scripture-Adams, JA Zack Nature medicine 7 (4), 459-464, 2001 | 239 | 2001 |
IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection DG Brooks, AM Lee, H Elsaesser, DB McGavern, MBA Oldstone The Journal of experimental medicine 205 (3), 533-541, 2008 | 203 | 2008 |
The role of IL-10 in regulating immunity to persistent viral infections EB Wilson, DG Brooks Negative Co-Receptors and Ligands, 39-65, 2011 | 199 | 2011 |
IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection DG Brooks, KB Walsh, H Elsaesser, MBA Oldstone Proceedings of the National Academy of Sciences 107 (7), 3018-3023, 2010 | 185 | 2010 |
Targeting type I interferon–mediated activation restores immune function in chronic HIV infection A Zhen, V Rezek, C Youn, B Lam, N Chang, J Rick, M Carrillo, H Martin, ... The Journal of clinical investigation 127 (1), 260-268, 2017 | 182 | 2017 |
Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection DG Brooks, DB McGavern, MBA Oldstone The Journal of clinical investigation 116 (6), 1675-1685, 2006 | 172 | 2006 |