Single turn peptide alpha helices with exceptional stability in water NE Shepherd, HN Hoang, G Abbenante, DP Fairlie Journal of the American Chemical Society 127 (9), 2974-2983, 2005 | 355 | 2005 |
New insights into growth hormone action MJ Waters, HN Hoang, DP Fairlie, RA Pelekanos, RJ Brown Journal of molecular endocrinology 36 (1), 1-7, 2006 | 282 | 2006 |
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency RS Harrison, NE Shepherd, HN Hoang, G Ruiz-Gómez, TA Hill, ... Proceedings of the National Academy of Sciences 107 (26), 11686-11691, 2010 | 197 | 2010 |
Comparative α‐Helicity of cyclic pentapeptides in water AD De Araujo, HN Hoang, WM Kok, F Diness, P Gupta, TA Hill, RW Driver, ... Angewandte Chemie International Edition 53 (27), 6965-6969, 2014 | 188 | 2014 |
Improving on nature: making a cyclic heptapeptide orally bioavailable DS Nielsen, HN Hoang, RJ Lohman, TA Hill, AJ Lucke, DJ Craik, ... Angewandte Chemie International Edition 53 (45), 12059-12063, 2014 | 153 | 2014 |
α-turn mimetics: short peptide α-helices composed of cyclic metallopentapeptide modules MJ Kelso, RL Beyer, HN Hoang, AS Lakdawala, JP Snyder, WV Oliver, ... Journal of the American Chemical Society 126 (15), 4828-4842, 2004 | 103 | 2004 |
The first solution stucture of a single α-helical turn. A pentapeptide α-helix stabilized by a metal clip MJ Kelso, HN Hoang, TG Appleton, DP Fairlie Journal of the American Chemical Society 122 (42), 10488-10489, 2000 | 87 | 2000 |
Modular α-helical mimetics with antiviral activity against respiratory syncitial virus NE Shepherd, HN Hoang, VS Desai, E Letouze, PR Young, DP Fairlie Journal of the American Chemical Society 128 (40), 13284-13289, 2006 | 77 | 2006 |
Flexibility versus rigidity for orally bioavailable cyclic hexapeptides DS Nielsen, RJ Lohman, HN Hoang, TA Hill, A Jones, AJ Lucke, ... ChemBioChem 16 (16), 2289-2293, 2015 | 72 | 2015 |
Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A DS Nielsen, HN Hoang, RJ Lohman, F Diness, DP Fairlie Organic letters 14 (22), 5720-5723, 2012 | 70 | 2012 |
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed TA Hill, RJ Lohman, HN Hoang, DS Nielsen, CCG Scully, WM Kok, L Liu, ... ACS medicinal chemistry letters 5 (10), 1148-1151, 2014 | 67 | 2014 |
Metal clips that induce unstructured pentapeptides to be α-helical in water MT Ma, HN Hoang, CCG Scully, TG Appleton, DP Fairlie Journal of the American Chemical Society 131 (12), 4505-4512, 2009 | 65 | 2009 |
Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1 T Rao, G Ruiz-Gómez, TA Hill, HN Hoang, DP Fairlie, JM Mason PLoS One 8 (3), e59415, 2013 | 54 | 2013 |
Metal clips induce folding of a short unstructured peptide into an α-helix via turn conformations in water. Kinetic versus thermodynamic products RL Beyer, HN Hoang, TG Appleton, DP Fairlie Journal of the American Chemical Society 126 (46), 15096-15105, 2004 | 53 | 2004 |
Selective hexapeptide agonists and antagonists for human complement C3a receptor CCG Scully, JS Blakeney, R Singh, HN Hoang, G Abbenante, RC Reid, ... Journal of medicinal chemistry 53 (13), 4938-4948, 2010 | 52 | 2010 |
Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists HN Hoang, K Song, TA Hill, DR Derksen, DJ Edmonds, WM Kok, ... Journal of medicinal chemistry 58 (9), 4080-4085, 2015 | 48 | 2015 |
A cyclic metallopeptide induces α helicity in short peptide fragments of thermolysin MJ Kelso, HN Hoang, W Oliver, N Sokolenko, DR March, TG Appleton, ... Angewandte Chemie 115 (4), 437-440, 2003 | 48 | 2003 |
Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice RS Harrison, G Ruiz-Gomez, TA Hill, SY Chow, NE Shepherd, ... Journal of medicinal chemistry 53 (23), 8400-8408, 2010 | 46 | 2010 |
Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability HN Hoang, TA Hill, DP Fairlie Angewandte Chemie 133 (15), 8466-8471, 2021 | 44 | 2021 |
Amyloid Formation from an α‐Helix Peptide Bundle Is Seeded by 310‐Helix Aggregates Y Singh, PC Sharpe, HN Hoang, AJ Lucke, AW McDowall, SP Bottomley, ... Chemistry–A European Journal 17 (1), 151-160, 2011 | 44 | 2011 |