Diabetes induces aberrant DNA methylation in the proximal tubules of the kidney T Marumo, S Yagi, W Kawarazaki, M Nishimoto, N Ayuzawa, A Watanabe, ... Journal of the American Society of Nephrology 26 (10), 2388-2397, 2015 | 109 | 2015 |
Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac1 M Nagase, N Ayuzawa, W Kawarazaki, K Ishizawa, K Ueda, S Yoshida, ... Hypertension 59 (2), 500-506, 2012 | 109 | 2012 |
Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation W Kawarazaki, M Nagase, S Yoshida, M Takeuchi, K Ishizawa, ... Journal of the American Society of Nephrology 23 (6), 997-1007, 2012 | 106 | 2012 |
Rac1-mediated activation of mineralocorticoid receptor in pressure overload–induced cardiac injury N Ayuzawa, M Nagase, K Ueda, M Nishimoto, W Kawarazaki, T Marumo, ... Hypertension 67 (1), 99-106, 2016 | 68 | 2016 |
Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency W Kawarazaki, R Mizuno, M Nishimoto, N Ayuzawa, D Hirohama, K Ueda, ... The Journal of Clinical Investigation 130 (8), 4152-4166, 2020 | 59 | 2020 |
Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor K Ueda, K Fujiki, K Shirahige, CE Gomez-Sanchez, T Fujita, M Nangaku, ... Biochemical and biophysical research communications 445 (1), 132-137, 2014 | 57 | 2014 |
Local mineralocorticoid receptor activation and the role of Rac1 in obesity-related diabetic kidney disease S Yoshida, K Ishizawa, N Ayuzawa, K Ueda, M Takeuchi, W Kawarazaki, ... Nephron Experimental Nephrology 126 (1), 16-24, 2014 | 44 | 2014 |
Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension K Ueda, M Nishimoto, D Hirohama, N Ayuzawa, W Kawarazaki, ... Hypertension 70 (1), 111-118, 2017 | 36 | 2017 |
Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension F Kawakami-Mori, M Nishimoto, L Reheman, W Kawarazaki, N Ayuzawa, ... JCI insight 3 (21), 2018 | 35 | 2018 |
Aldosterone is essential for angiotensin II-induced upregulation of pendrin D Hirohama, N Ayuzawa, K Ueda, M Nishimoto, W Kawarazaki, ... Journal of the American Society of Nephrology 29 (1), 57-68, 2018 | 35 | 2018 |
Podocyte injury augments intrarenal angiotensin II generation and sodium retention in a megalin-dependent manner M Koizumi, K Ueda, F Niimura, A Nishiyama, M Yanagita, A Saito, ... Hypertension 74 (3), 509-517, 2019 | 27 | 2019 |
Two Mineralocorticoid Receptor–Mediated Mechanisms of Pendrin Activation in Distal Nephrons N Ayuzawa, M Nishimoto, K Ueda, D Hirohama, W Kawarazaki, ... Journal of the American Society of Nephrology 31 (4), 748-764, 2020 | 26 | 2020 |
Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study M Nishimoto, H Ohtsu, T Marumo, W Kawarazaki, N Ayuzawa, K Ueda, ... Hypertension Research 42 (4), 514-521, 2019 | 26 | 2019 |
Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells S Oba, N Ayuzawa, M Nishimoto, W Kawarazaki, K Ueda, D Hirohama, ... Scientific reports 8 (1), 16338, 2018 | 22 | 2018 |
Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney A Watanabe, T Marumo, W Kawarazaki, M Nishimoto, N Ayuzawa, ... American Journal of Physiology-Renal Physiology 314 (4), F551-F560, 2018 | 19 | 2018 |
Mineralocorticoid receptor activation as an etiological factor in kidney diseases K Ueda, M Nagase Clinical and experimental nephrology 18, 16-23, 2014 | 12 | 2014 |
Successful treatment of acute kidney injury in patients with idiopathic nephrotic syndrome using human atrial natriuretic Peptide K Ueda, J Hirahashi, G Seki, M Tanaka, N Kushida, Y Takeshima, ... Internal Medicine 53 (8), 865-869, 2014 | 10 | 2014 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading S Yoshida, K Ishizawa, N Ayuzawa, K Ueda, M Takeuchi, W Kawarazaki, ... Clinical and experimental nephrology 18, 593-599, 2014 | 6 | 2014 |
Successful Treatment of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis With Eicosapentaenoic Acid J Hirahashi, A Jo, K Ueda, A Tojo, T Fujita Annals of internal medicine 156 (10), 755-756, 2012 | 5 | 2012 |
A novel compound heterozygous mutation of Gitelman's syndrome in Japan, as diagnosed by an extraordinary response of the fractional excretion rate of chloride in the … K Ueda, N Makita, H Kawarazaki, T Fujiwara, S Unuma, T Monkawa, ... Internal Medicine 51 (12), 1549-1553, 2012 | 4 | 2012 |