Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions C Summerford, RJ Samulski Journal of virology 72 (2), 1438-1445, 1998 | 1833 | 1998 |
Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus X Xiao, J Li, RJ Samulski Journal of virology 72 (3), 2224-2232, 1998 | 1743 | 1998 |
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield S Zolotukhin, BJ Byrne, E Mason, I Zolotukhin, M Potter, K Chesnut, ... Gene therapy 6 (6), 973-985, 1999 | 1574 | 1999 |
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain MG Kaplitt, P Leone, RJ Samulski, X Xiao, DW Pfaff, KL O'Malley, ... Nature genetics 8 (2), 148-154, 1994 | 1547 | 1994 |
Site-specific integration by adeno-associated virus. RM Kotin, M Siniscalco, RJ Samulski, XD Zhu, L Hunter, CA Laughlin, ... Proceedings of the National Academy of Sciences 87 (6), 2211-2215, 1990 | 1411 | 1990 |
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression RJ Samulski, LS Chang, T Shenk Journal of virology 63 (9), 3822-3828, 1989 | 1202 | 1989 |
Adeno-associated virus serotypes: vector toolkit for human gene therapy Z Wu, A Asokan, RJ Samulski Molecular therapy 14 (3), 316-327, 2006 | 1177 | 2006 |
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector X Xiao, J Li, RJ Samulski Journal of virology 70 (11), 8098-8108, 1996 | 1149 | 1996 |
Targeted integration of adeno‐associated virus (AAV) into human chromosome 19. RJ Samulski, X Zhu, X Xiao, JD Brook, DE Housman, N Epstein, ... The EMBO journal 10 (12), 3941-3950, 1991 | 1108 | 1991 |
αVβ5 integrin: a co-receptor for adeno-associated virus type 2 infection C Summerford, JS Bartlett, RJ Samulski Nature medicine 5 (1), 78-82, 1999 | 1043 | 1999 |
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors FK Ferrari, T Samulski, T Shenk, RJ Samulski Journal of virology 70 (5), 3227-3234, 1996 | 1040 | 1996 |
Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity JE Rabinowitz, F Rolling, C Li, H Conrath, W Xiao, X Xiao, RJ Samulski Journal of virology 76 (2), 791-801, 2002 | 1031 | 2002 |
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis DM McCarty, PE Monahan, RJ Samulski Gene therapy 8 (16), 1248-1254, 2001 | 1026 | 2001 |
Engineering adeno-associated virus vectors for gene therapy C Li, RJ Samulski Nature Reviews Genetics 21 (4), 255-272, 2020 | 882 | 2020 |
Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors JS Bartlett, R Wilcher, RJ Samulski Journal of virology 74 (6), 2777-2785, 2000 | 804 | 2000 |
AAV transduction vectors N Muzyczka, PL Hermonat, KI Berns, RJ Samulski US Patent 5,139,941, 1992 | 792 | 1992 |
Dystrophin immunity in Duchenne's muscular dystrophy JR Mendell, K Campbell, L Rodino-Klapac, Z Sahenk, C Shilling, S Lewis, ... New England Journal of Medicine 363 (15), 1429-1437, 2010 | 738 | 2010 |
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo DM McCarty, H Fu, PE Monahan, CE Toulson, P Naik, RJ Samulski Gene therapy 10 (26), 2112-2118, 2003 | 697 | 2003 |
Production and characterization of adeno-associated viral vectors JC Grieger, VW Choi, RJ Samulski Nature protocols 1 (3), 1412-1428, 2006 | 678 | 2006 |
Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. RJ Samulski, KI Berns, M Tan, N Muzyczka Proceedings of the National Academy of Sciences 79 (6), 2077-2081, 1982 | 647 | 1982 |