| Structural basis of FFAT motif-mediated ER targeting SE Kaiser, JH Brickner, AR Reilein, TD Fenn, P Walter, AT Brunger Structure 13 (7), 1035-1045, 2005 | 287 | 2005 |
| Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools SE Kaiser, BE Riley, TA Shaler, RS Trevino, CH Becker, H Schulman, ... Nature methods 8 (8), 691-696, 2011 | 283 | 2011 |
| Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease MS Hipp, CN Patel, K Bersuker, BE Riley, SE Kaiser, TA Shaler, ... Journal of Cell Biology 196 (5), 573-587, 2012 | 197 | 2012 |
| Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate … BE Riley, SE Kaiser, TA Shaler, ACY Ng, T Hara, MS Hipp, K Lage, ... Journal of Cell Biology 191 (3), 537-552, 2010 | 184 | 2010 |
| Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway AM Taherbhoy, SW Tait, SE Kaiser, AH Williams, A Deng, A Nourse, ... Molecular cell 44 (3), 451-461, 2011 | 164 | 2011 |
| The unfolded protein response triggers site-specific regulatory ubiquitylation of 40S ribosomal proteins R Higgins, JM Gendron, L Rising, R Mak, K Webb, SE Kaiser, N Zuzow, ... Molecular cell 59 (1), 35-49, 2015 | 149 | 2015 |
| Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and … S Crosignani, P Bingham, P Bottemanne, H Cannelle, S Cauwenberghs, ... Journal of medicinal chemistry 60 (23), 9617-9629, 2017 | 126 | 2017 |
| Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex Y Sato, H Fujita, A Yoshikawa, M Yamashita, A Yamagata, SE Kaiser, ... Proceedings of the National Academy of Sciences 108 (51), 20520-20525, 2011 | 119 | 2011 |
| Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures SE Kaiser, K Mao, AM Taherbhoy, S Yu, JL Olszewski, DM Duda, ... Nature structural & molecular biology 19 (12), 1242-1249, 2012 | 116 | 2012 |
| Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A CL Quinlan, SE Kaiser, B Bolaños, D Nowlin, R Grantner, ... Nature chemical biology 13 (7), 785-792, 2017 | 103 | 2017 |
| ALIX is a Lys63-specific polyubiquitin binding protein that functions in retrovirus budding DP Dowlatshahi, V Sandrin, S Vivona, TA Shaler, SE Kaiser, F Melandri, ... Developmental cell 23 (6), 1247-1254, 2012 | 93 | 2012 |
| Human stoned B interacts with AP‐2 and synaptotagmin and facilitates clathrin‐coated vesicle uncoating K Walther, M Krauss, MK Diril, S Lemke, D Ricotta, S Höning, S Kaiser, ... EMBO reports, 2001 | 78 | 2001 |
| The structure of the yeast plasma membrane SNARE complex reveals destabilizing water-filled cavities P Strop, SE Kaiser, M Vrljic, AT Brunger Journal of Biological Chemistry 283 (2), 1113-1119, 2008 | 56 | 2008 |
| Chemoselective preparation of clickable aryl sulfonyl fluoride monomers: A toolbox of highly functionalized intermediates for chemical biology probe synthesis O Fadeyi, MD Parikh, MZ Chen, RE Kyne Jr, AP Taylor, I O'Doherty, ... ChemBioChem 17 (20), 1925-1930, 2016 | 46 | 2016 |
| Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1 K Ryan, B Bolaňos, M Smith, PB Palde, PD Cuenca, TL VanArsdale, ... Journal of Biological Chemistry 296, 2021 | 44 | 2021 |
| Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1 SE Kaiser, Y Qiu, JE Coats, K Mao, DJ Klionsky, BA Schulman Autophagy 9 (5), 778-780, 2013 | 37 | 2013 |
| Structure-based drug design and synthesis of PI3Kα-selective inhibitor (PF-06843195) H Cheng, STM Orr, S Bailey, A Brooun, P Chen, JG Deal, YL Deng, ... Journal of medicinal chemistry 64 (1), 644-661, 2020 | 27 | 2020 |
| Autophagy inhibition engages Nrf2-p62 Ub-associated signaling BE Riley, SE Kaiser, RR Kopito Autophagy 7 (3), 2011 | 25 | 2011 |
| Binding to E1 and E3 is mutually exclusive for the human autophagy E2 Atg3 Y Qiu, K Hofmann, JE Coats, BA Schulman, SE Kaiser Protein Science 22 (12), 1691-1697, 2013 | 24 | 2013 |
| Ubiquitin-like modifiers AM Taherbhoy, BA Schulman, SE Kaiser Essays in biochemistry 52, 51-63, 2012 | 23 | 2012 |
