Targets Heterocycl J Elguero, P Goya, N Jagerovic, AMS Silva Syst 6, 52-98, 2002 | 341 | 2002 |
An overview on medicinal chemistry of synthetic and natural derivatives of cannabidiol P Morales, PH Reggio, N Jagerovic Frontiers in pharmacology 8, 237543, 2017 | 192 | 2017 |
Targeting cannabinoid CB2 receptors in the central nervous system. Medicinal chemistry approaches with focus on neurodegenerative disorders G Navarro, P Morales, C Rodríguez-Cueto, J Fernández-Ruiz, ... Frontiers in Neuroscience 10, 211100, 2016 | 151 | 2016 |
Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-3-hexyl-1H-1, 2, 4-triazole–LH 21 FJ Pavon, A Bilbao, L Hernández-Folgado, A Cippitelli, N Jagerovic, ... Neuropharmacology 51 (2), 358-366, 2006 | 134 | 2006 |
Dynamic NMR study of the mechanisms of double, triple, and quadruple proton and deuteron transfer in cyclic hydrogen bonded solids of pyrazole derivatives O Klein, F Aguilar-Parrilla, JM Lopez, N Jagerovic, J Elguero, HH Limbach Journal of the American Chemical Society 126 (37), 11718-11732, 2004 | 125 | 2004 |
Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review P Morales, P Goya, N Jagerovic, L Hernandez-Folgado Cannabis and Cannabinoid Research 1 (1), 22-30, 2016 | 101 | 2016 |
Central versus peripheral antagonism of cannabinoid CB1 receptor in obesity: effects of LH‐21, a peripherally acting neutral cannabinoid receptor antagonist, in Zucker rats FJ Pavon, A Serrano, V Perez‐Valero, N Jagerovic, ... Journal of neuroendocrinology 20, 116-123, 2008 | 94 | 2008 |
A solid-state NMR, X-ray diffraction, and ab initio computational study of hydrogen-bond structure and dynamics of pyrazole-4-carboxylic acid chains C Foces-Foces, A Echevarría, N Jagerovic, I Alkorta, J Elguero, U Langer, ... Journal of the American Chemical Society 123 (32), 7898-7906, 2001 | 94 | 2001 |
Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes G Navarro, I Reyes-Resina, R Rivas-Santisteban, VS de Medina, ... Biochemical pharmacology 157, 148-158, 2018 | 90 | 2018 |
Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the μ-opioid receptor and I2–imidazoline binding sites C Dardonville, C Fernandez-Fernandez, SL Gibbons, GJ Ryan, ... Bioorganic & medicinal chemistry 14 (19), 6570-6580, 2006 | 89 | 2006 |
Pyrazoles as drugs: facts and fantasies J Elguero, P Goya, N Jagerovic, AMS Silva Targets in Heterocyclic Systems 6, 52-98, 2002 | 85 | 2002 |
Discovery of 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole, a Novel in Vivo Cannabinoid Antagonist Containing a 1,2,4-Triazole Motif N Jagerovic, L Hernandez-Folgado, I Alkorta, P Goya, M Navarro, ... Journal of Medicinal Chemistry 47 (11), 2939-2942, 2004 | 84 | 2004 |
Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update P Morales, L Hernandez-Folgado, P Goya, N Jagerovic Expert opinion on therapeutic patents 26 (7), 843-856, 2016 | 83 | 2016 |
Synthesis and molecular structure of 3-(2-benzyloxy-6-hydroxyphenyl)-5-styrylpyrazoles. Reaction of 2-styrylchromones and hydrazine hydrate DCGA Pinto, AMS Silva, JAS Cavaleiro, C Foces-Foces, AL Llamas-Saiz, ... Tetrahedron 55 (33), 10187-10200, 1999 | 73 | 1999 |
Use of the chlorophyll derivative, purpurin-18, for syntheses of sensitizers for use in photodynamic therapy SJH Lee, N Jagerovic, KM Smith Journal of the Chemical Society, Perkin Transactions 1, 2369-2377, 1993 | 70 | 1993 |
Anti‐obesity efficacy of LH‐21, a cannabinoid CB1 receptor antagonist with poor brain penetration, in diet‐induced obese rats M Alonso, A Serrano, M Vida, A Crespillo, L Hernandez‐Folgado, ... British journal of pharmacology 165 (7), 2274-2291, 2012 | 67 | 2012 |
CB1 cannabinoid antagonists: structure-activity relationships and potential therapeutic applications N Jagerovic, C Fernandez-Fernandez, P Goya Current topics in medicinal chemistry 8 (3), 205-230, 2008 | 67 | 2008 |
Photosensitization with derivatives of chlorin p6 D Kessel, K Woodburn, CJ Gomer, N Jagerovic, KM Smith Journal of Photochemistry and Photobiology B: Biology 28 (1), 13-18, 1995 | 66 | 1995 |
The Colors of C60 Solutions J Catalán, JL Saiz, JL Laynez, N Jagerovic, J Elguero Angewandte Chemie International Edition in English 34 (1), 105-107, 1995 | 65 | 1995 |
Trifluoromethyl and perfluoroalkyl derivatives of azoles. A review J Elguero, A Fruchier, N Jagerovic, A Werner Organic preparations and procedures international 27 (1), 33-74, 1995 | 58 | 1995 |