关注
Dr. Renata Kasprzyk
Dr. Renata Kasprzyk
University of Konstanz
在 fuw.edu.pl 的电子邮件经过验证
标题
引用次数
引用次数
年份
Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies
MR Baranowski, A Nowicka, AM Rydzik, M Warminski, R Kasprzyk, ...
The Journal of organic chemistry 80 (8), 3982-3997, 2015
412015
2′-O-Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to …
K Drazkowska, R Tomecki, M Warminski, N Baran, D Cysewski, A Depaix, ...
Nucleic acids research 50 (16), 9051-9071, 2022
322022
Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase
R Kasprzyk, TJ Spiewla, M Smietanski, S Golojuch, L Vangeel, ...
Antiviral Research 193, 105142, 2021
272021
Structural insights into the interaction of clinically relevant phosphorothioate mRNA cap analogs with translation initiation factor 4E reveal stabilization via electrostatic …
M Warminski, J Kowalska, E Nowak, D Kubacka, R Tibble, R Kasprzyk, ...
ACS Chemical Biology 16 (2), 334-343, 2021
202021
7-Methylguanosine monophosphate analogues with 5′-(1, 2, 3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase
M Kozarski, D Kubacka, BA Wojtczak, R Kasprzyk, MR Baranowski, ...
Bioorganic & Medicinal Chemistry 26 (1), 191-199, 2018
182018
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
M Zmudzinski, W Rut, K Olech, J Granda, M Giurg, M Burda-Grabowska, ...
Scientific reports 13 (1), 9161, 2023
162023
Acetylpyrene-labelled 7-methylguanine nucleotides: unusual fluorescence properties and application to decapping scavenger activity monitoring
R Kasprzyk, J Kowalska, Z Wieczorek, M Szabelski, R Stolarski, ...
Organic & Biomolecular Chemistry 14 (16), 3863-3868, 2016
142016
Enzymatic assays to explore viral mRNA capping machinery
R Kasprzyk, J Jemielity
ChemBioChem 22 (23), 3236-3253, 2021
132021
Fluorescent Turn‐On Probes for the Development of Binding and Hydrolytic Activity Assays for mRNA Cap‐Recognizing Proteins
R Kasprzyk, BJ Starek, S Ciechanowicz, D Kubacka, J Kowalska, ...
Chemistry–A European Journal 25 (27), 6728-6740, 2019
122019
Exploring the potential of phosphotriazole 5′ mRNA cap analogues as efficient translation initiators
S Walczak, PJ Sikorski, R Kasprzyk, J Kowalska, J Jemielity
Organic & Biomolecular Chemistry 16 (36), 6741-6748, 2018
112018
N1-Propargylguanosine Modified mRNA Cap Analogs: Synthesis, reactivity, and applications to the study of cap-binding proteins
M Kopcial, BA Wojtczak, R Kasprzyk, J Kowalska, J Jemielity
Molecules 24 (10), 1899, 2019
92019
Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications
N Kleczewska, PJ Sikorski, Z Warminska, L Markiewicz, R Kasprzyk, ...
Chemical Science 12 (30), 10242-10251, 2021
82021
Direct High‐Throughput Screening Assay for mRNA Cap Guanine‐N7 Methyltransferase Activity
R Kasprzyk, M Fido, A Mamot, P Wanat, M Smietanski, M Kopcial, ...
Chemistry–A European Journal 26 (49), 11266-11275, 2020
72020
Exploring tryptamine conjugates as pronucleotides of phosphate-modified 7-methylguanine nucleotides targeting cap-dependent translation
S Golojuch, M Kopcial, D Strzelecka, R Kasprzyk, N Baran, PJ Sikorski, ...
Bioorganic & Medicinal Chemistry 28 (13), 115523, 2020
72020
ExciTides: NTP-derived probes for monitoring pyrophosphatase activity based on excimer-to-monomer transitions
P Wanat, R Kasprzyk, M Kopcial, PJ Sikorski, D Strzelecka, J Jemielity, ...
Chemical communications 54 (70), 9773-9776, 2018
72018
Evaluation of carboxyfluorescein-labeled 7-methylguanine nucleotides as probes for studying cap-binding proteins by fluorescence anisotropy
A Wojtczak, R Kasprzyk, M Warmiński, K Ubych, D Kubacka, PJ Sikorski, ...
Scientific Reports 11 (1), 7687, 2021
62021
Fluorescence anisotropy assay with guanine nucleotides provides access to functional analysis of Gαi1 proteins
A Pepanian, P Sommerfeld, R Kasprzyk, T Kühl, FA Binbay, C Hauser, ...
Analytical Chemistry 94 (41), 14410-14418, 2022
22022
Fluorescence-based activity screening assay reveals small molecule inhibitors of vaccinia virus mRNA decapping enzyme D9
M Bednarczyk, JK Peters, R Kasprzyk, J Starek, M Warminski, T Spiewla, ...
ACS Chemical Biology 17 (6), 1460-1471, 2022
22022
A desthiobiotin labelled NAD+ analogue to uncover Poly (ADP‐ribose) polymerase 1 protein targets
S Rieth, D Spliesgar, J Orth, M Lehner, R Kasprzyk, F Stengel, A Marx
ChemBioChem, e202300797, 2024
12024
Cell-permeable nicotinamide adenine dinucleotides for exploration of cellular protein ADP-ribosylation
R Kasprzyk, S Rieth, P Heid, F Stengel, A Marx
2024
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