How specific are the conformation-specific α-synuclein antibodies? Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized … ST Kumar, S Jagannath, C Francois, H Vanderstichele, E Stoops, ... Neurobiology of Disease 146, 105086, 2020 | 121 | 2020 |
Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection NR Roan, H Liu, SM Usmani, J Neidleman, JA Müller, A Avila-Herrera, ... Journal of virology 88 (13), 7221-7234, 2014 | 70 | 2014 |
Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM U Cendrowska, PJ Silva, N Ait-Bouziad, M Müller, ZP Guven, S Vieweg, ... Proceedings of the National Academy of Sciences 117 (12), 6866-6874, 2020 | 58 | 2020 |
A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving … ST Kumar, S Donzelli, A Chiki, MMK Syed, HA Lashuel Journal of Neurochemistry 153 (1), 103-119, 2020 | 56 | 2020 |
A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: towards improving … ST Kumar, S Donzelli, A Chiki, K Syed Muhammed Muazzam, HA Lashuel bioRxiv, 772160, 2019 | 56 | 2019 |
Pattern recognition with a fibril-specific antibody fragment reveals the surface variability of natural amyloid fibrils C Haupt, M Bereza, ST Kumar, B Kieninger, I Morgado, P Hortschansky, ... Journal of molecular biology 408 (3), 529-540, 2011 | 48 | 2011 |
Structural characterization of amyloid fibrils from the human parathyroid hormone M Gopalswamy, A Kumar, J Adler, M Baumann, M Henze, ST Kumar, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (4), 249-257, 2015 | 44 | 2015 |
Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology J Burtscher, JC Copin, J Rodrigues, ST Kumar, A Chiki, IG de Suduiraut, ... Neurobiology of aging 83, 11-20, 2019 | 43 | 2019 |
Amyloid fibril recognition with the conformational B10 antibody fragment depends on electrostatic interactions C Haupt, I Morgado, ST Kumar, C Parthier, M Bereza, P Hortschansky, ... Journal of molecular biology 405 (2), 341-348, 2011 | 39 | 2011 |
A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity ST Kumar, AL Mahul-Mellier, RN Hegde, G Rivière, R Moons, ... Science Advances 8 (17), eabn0044, 2022 | 35 | 2022 |
Structure and Biomedical Applications of Amyloid Oligomer Nanoparticles ST Kumar, J Meinhardt, AK Fuchs, T Aumüller, J Leppert, B Büchele, ... ACS nano 8 (11), 11042-11052, 2014 | 30 | 2014 |
Artificial intelligence–coupled plasmonic infrared sensor for detection of structural protein biomarkers in neurodegenerative diseases D Kavungal, P Magalhães, ST Kumar, R Kolla, HA Lashuel, H Altug Science Advances 9 (28), eadg9644, 2023 | 25 | 2023 |
Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage ST Kumar, S Nazarov, S Porta, N Maharjan, U Cendrowska, M Kabani, ... Nature Neuroscience 26 (6), 983-996, 2023 | 22 | 2023 |
Solvent Removal Induces a Reversible β-to-α Switch in Oligomeric Aβ Peptide ST Kumar, J Leppert, P Bellstedt, C Wiedemann, M Fändrich, M Görlach Journal of molecular biology 428 (2), 268-273, 2016 | 18 | 2016 |
Disulfide conformation and design at helix N‐termini S Indu, ST Kumar, S Thakurela, M Gupta, RM Bhaskara, C Ramakrishnan, ... Proteins: Structure, Function, and Bioinformatics 78 (5), 1228-1242, 2010 | 17 | 2010 |
Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases MF Altay, ST Kumar, J Burtscher, S Jagannath, C Strand, Y Miki, ... npj Parkinson's Disease 9 (1), 161, 2023 | 11 | 2023 |
Molecular architecture of Aβ fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aβ plaque formation M Garvey, M Baumann, M Wulff, ST Kumar, D Markx, I Morgado, ... Amyloid 23 (2), 76-85, 2016 | 9 | 2016 |
Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo S Donzelli, SA OSullivan, AL Mahul-Mellier, A Ulusoy, G Fusco, ST Kumar, ... BioRxiv, 2023.03. 24.534149, 2023 | 6 | 2023 |
Chronic corticosterone enhancement aggravates alpha-synuclein brain spreading pathology and substantia nigra neurodegeneration in mice J Burtscher, JC Copin, J Rodrigues, SK Thangaraj, A Chiki, ... bioRxiv, 469999, 2018 | 1 | 2018 |
Deep learning augmented nanoplasmonic infrared sensor for structural protein biomarker-based detection of neurodegenerative diseases D Kavungal, P Magalhães, ST Kumar, R Kolla, H Lashuel, H Altug Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI …, 2024 | | 2024 |