Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis M Mohrin, E Bourke, D Alexander, MR Warr, K Barry-Holson, MM Le Beau, ... Cell stem cell 7 (2), 174-185, 2010 | 690 | 2010 |
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells J Flach, ST Bakker, M Mohrin, PC Conroy, EM Pietras, D Reynaud, ... Nature 512 (7513), 198-202, 2014 | 626 | 2014 |
A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging M Mohrin, J Shin, Y Liu, K Brown, H Luo, Y Xi, CM Haynes, D Chen Science 347 (6228), 1374-1377, 2015 | 474 | 2015 |
SIRT3 reverses aging-associated degeneration K Brown, S Xie, X Qiu, M Mohrin, J Shin, Y Liu, D Zhang, DT Scadden, ... Cell reports 3 (2), 319-327, 2013 | 462 | 2013 |
DNA-damage response in tissue-specific and cancer stem cells C Blanpain, M Mohrin, PA Sotiropoulou, E Passegué Cell stem cell 8 (1), 16-29, 2011 | 402 | 2011 |
SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease J Shin, M He, Y Liu, S Paredes, L Villanova, K Brown, X Qiu, N Nabavi, ... Cell reports 5 (3), 654-665, 2013 | 281 | 2013 |
Mitochondrial stress-initiated aberrant activation of the NLRP3 inflammasome regulates the functional deterioration of hematopoietic stem cell aging H Luo, WC Mu, R Karki, HH Chiang, M Mohrin, JJ Shin, R Ohkubo, K Ito, ... Cell reports 26 (4), 945-954. e4, 2019 | 120 | 2019 |
The mitochondrial unfolded protein response is activated upon hematopoietic stem cell exit from quiescence M Mohrin, A Widjaja, Y Liu, H Luo, D Chen Aging Cell 17 (3), e12756, 2018 | 59 | 2018 |
The mitochondrial metabolic checkpoint and aging of hematopoietic stem cells M Mohrin, D Chen Current opinion in hematology 23 (4), 318-324, 2016 | 42 | 2016 |
Sirtuins, tissue maintenance, and tumorigenesis M Mohrin, D Chen Genes & Cancer 4 (3-4), 76-81, 2013 | 10 | 2013 |
Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells M Mohrin, J Liu, J Zavala‐Solorio, S Bhargava, J Maxwell Trumble, A Brito, ... Aging Cell 20 (3), e13313, 2021 | 9 | 2021 |
Mito–managing ROS & redox to reboot the immune system: tapping mitochondria & redox management to extend the reach of hematopoietic stem cell transplantation M Mohrin Free Radical Biology and Medicine 165, 38-53, 2021 | 6 | 2021 |
Reversing stem cell aging J Shin, M Mohrin, D Chen Oncotarget 6 (17), 14723, 2015 | 5 | 2015 |
Exploring human skin aging at the single-cell level M Mohrin, H Jasper Developmental Cell 56 (3), 253-254, 2021 | 3 | 2021 |
Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity M Mohrin, J Liu, J Zavala-Solorio, S Bhargava, JM Trumble, A Brito, D Hu, ... bioRxiv, 2020.02. 05.936310, 2020 | 1 | 2020 |
DNA damage response and DNA repair during hematopoietic differentiation and development M Mohrin University of California, San Francisco, 2011 | | 2011 |