Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide DR Cochrane, S Bernales, BM Jacobsen, DM Cittelly, EN Howe, ... Breast Cancer Research 16, 1-19, 2014 | 436 | 2014 |
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons W Cerpa, JA Godoy, I Alfaro, GG Farías, MJ Metcalfe, R Fuentealba, ... Journal of Biological Chemistry 283 (9), 5918-5927, 2008 | 264 | 2008 |
Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons GG Farías, IE Alfaro, W Cerpa, CP Grabowski, JA Godoy, C Bonansco, ... Journal of Biological Chemistry 284 (23), 15857-15866, 2009 | 261 | 2009 |
Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses L Varela-Nallar, IE Alfaro, FG Serrano, J Parodi, NC Inestrosa Proceedings of the National Academy of Sciences 107 (49), 21164-21169, 2010 | 250 | 2010 |
Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration‐resistant prostate cancer J Guerrero, IE Alfaro, F Gómez, AA Protter, S Bernales The Prostate 73 (12), 1291-1305, 2013 | 131 | 2013 |
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function L Varela-Nallar, CP Grabowski, IE Alfaro, AR Alvarez, NC Inestrosa Neural development 4, 1-15, 2009 | 131 | 2009 |
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model JW Steele, ML Lachenmayer, S Ju, A Stock, J Liken, SH Kim, LM Delgado, ... Molecular psychiatry 18 (8), 889-897, 2013 | 125 | 2013 |
Chaperone mediated autophagy in the crosstalk of neurodegenerative diseases and metabolic disorders IE Alfaro, A Albornoz, A Molina, J Moreno, K Cordero, A Criollo, M Budini Frontiers in Endocrinology 9, 778, 2019 | 95 | 2019 |
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain JW Steele, S Ju, ML Lachenmayer, J Liken, A Stock, SH Kim, LM Delgado, ... Molecular psychiatry 18 (8), 882-888, 2013 | 91 | 2013 |
Up-regulation of CD95 (Apo-1/Fas) is associated with spermatocyte apoptosis during the first round of spermatogenesis in the rat C Lizama, I Alfaro, JG Reyes, RD Moreno Apoptosis 12, 499-512, 2007 | 87 | 2007 |
Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation A Montoya, D Elgueta, J Campos, O Chovar, P Falcón, S Matus, I Alfaro, ... Journal of Neuroinflammation 16, 1-19, 2019 | 73 | 2019 |
Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate … M Giorgetti, JA Gibbons, S Bernales, IE Alfaro, CD La Rochelle, ... Journal of Pharmacology and Experimental Therapeutics 333 (3), 748-757, 2010 | 64 | 2010 |
Kinetics, molecular basis, and differentiation of l-lactate transport in spermatogenic cells S Brauchi, MC Rauch, IE Alfaro, C Cea, II Concha, DJ Benos, JG Reyes American journal of physiology-Cell physiology 288 (3), C523-C534, 2005 | 63 | 2005 |
Chaperone mediated autophagy degrades TDP-43 protein and is affected by TDP-43 aggregation F Ormeño, J Hormazabal, J Moreno, F Riquelme, J Rios, A Criollo, ... Frontiers in molecular neuroscience 13, 19, 2020 | 47 | 2020 |
Thiazolidinediones promote axonal growth through the activation of the JNK pathway RA Quintanilla, JA Godoy, I Alfaro, D Cabezas, R Bernhardi, M Bronfman, ... PloS one 8 (5), e65140, 2013 | 37 | 2013 |
Connexin-46 contained in extracellular vesicles enhance malignancy features in breast cancer cells RA Acuña, M Varas-Godoy, VM Berthoud, IE Alfaro, MA Retamal Biomolecules 10 (5), 676, 2020 | 29 | 2020 |
Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors PS Jadhavar, SA Ramachandran, E Riquelme, A Gupta, KP Quinn, ... Bioorganic & medicinal chemistry letters 26 (21), 5222-5228, 2016 | 26 | 2016 |
PP32 and SET/TAF-Iβ proteins regulate the acetylation of newly synthesized histone H4 F Saavedra, C Rivera, E Rivas, P Merino, D Garrido, S Hernández, ... Nucleic Acids Research 45 (20), 11700-11710, 2017 | 23 | 2017 |
Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors SA Ramachandran, PS Jadhavar, SK Miglani, MP Singh, DP Kalane, ... Bioorganic & Medicinal Chemistry Letters 27 (10), 2153-2160, 2017 | 23 | 2017 |
Drieu La Rochelle C, Cremers T, Altar CA, Wronski R, Hutter-Paier B, Protter AA (2010) Cognition-enhancing properties of Dimebon in a rat novel object recognition task are … M Giorgetti, JA Gibbons, S Bernales, IE Alfaro J Pharmacol Exp Ther 333 (3), 748-57, 0 | 18 | |