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Diacylglycerol, when simplicity becomes complex S Carrasco, I Mérida Trends in biochemical sciences 32 (1), 27-36, 2007 | 456 | 2007 |
Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase C Jimenez, DR Jones, P Rodríguez‐Viciana, A Gonzalez‐García, ... The EMBO journal, 1998 | 333 | 1998 |
Identification of insulin-like growth factor-binding protein-1 as a potential physiological substrate for human stromelysin-3 S Manes, E Mira, M del Mar Barbacid, A Ciprés, P Fernández-Resa, ... Journal of Biological Chemistry 272 (41), 25706-25712, 1997 | 279 | 1997 |
Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1α-induced lymphocyte polarization and chemotaxis M Vicente-Manzanares, M Rey, DR Jones, D Sancho, M Mellado, ... The Journal of Immunology 163 (7), 4001-4012, 1999 | 192 | 1999 |
Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid A Ávila-Flores, T Santos, E Rincón, I Mérida Journal of Biological Chemistry 280 (11), 10091-10099, 2005 | 179 | 2005 |
Diacylglycerol-dependent binding recruits PKCθ and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes S Carrasco, I Merida Molecular biology of the cell 15 (6), 2932-2942, 2004 | 175 | 2004 |
Role of diacylglycerol kinase α in the attenuation of receptor signaling MA Sanjuán, DR Jones, M Izquierdo, I Mérida The Journal of cell biology 153 (1), 207-220, 2001 | 171 | 2001 |
Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes R Alonso, C Mazzeo, MC Rodríguez, M Marsh, A Fraile-Ramos, V Calvo, ... Cell Death & Differentiation 18 (7), 1161-1173, 2011 | 168 | 2011 |
Glucose transport and antilipolysis are differentially regulated by the polar head group of an insulin-sensitive glycophospholipid. KL Kelly, JM Mato, I Merida, L Jarett Proceedings of the National Academy of Sciences 84 (18), 6404-6407, 1987 | 160 | 1987 |
A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex T Clairfeuille, C Mas, ASM Chan, Z Yang, M Tello-Lafoz, M Chandra, ... Nature structural & molecular biology 23 (10), 921-932, 2016 | 157 | 2016 |
Diacylglycerol kinase α regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes R Alonso, MC Rodríguez, J Pindado, E Merino, I Mérida, M Izquierdo Journal of Biological Chemistry 280 (31), 28439-28450, 2005 | 152 | 2005 |
IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase. I Merida, E Diez, GN Gaulton Journal of immunology (Baltimore, Md.: 1950) 147 (7), 2202-2207, 1991 | 150 | 1991 |
Phosphatidic Acid Generation through Interleukin 2 (IL-2)-induced α-Diacylglycerol Kinase Activation Is an Essential Step in IL-2-mediated Lymphocyte Proliferation (∗) I Flores, T Casaseca, C Martinez-A, H Kanoh, I Merida Journal of Biological Chemistry 271 (17), 10334-10340, 1996 | 143 | 1996 |
Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension J Aragonés, DR Jones, S Martın, MA San Juan, A Alfranca, F Vidal, ... Journal of Biological Chemistry 276 (13), 10548-10555, 2001 | 133 | 2001 |
Essential function for the GTPase TC21 in homeostatic antigen receptor signaling P Delgado, B Cubelos, E Calleja, N Martínez-Martín, A Ciprés, I Mérida, ... Nature immunology 10 (8), 880-888, 2009 | 130 | 2009 |
T cell activation in vivo targets diacylglycerol kinase α to the membrane: a novel mechanism for Ras attenuation MA Sanjuán, B Pradet-Balade, DR Jones, C Martínez-A, JC Stone, ... The Journal of Immunology 170 (6), 2877-2883, 2003 | 127 | 2003 |
Diacylglycerol is required for the formation of COPI vesicles in the Golgi-to-ER transport pathway I Fernández-Ulibarri, M Vilella, F Lázaro-Diéguez, E Sarri, SE Martínez, ... Molecular biology of the cell 18 (9), 3250-3263, 2007 | 111 | 2007 |
Regulation of interleukin 2-dependent growth responses by glycosylphosphatidylinositol molecules. I Merida, JC Pratt, GN Gaulton Proceedings of the National Academy of Sciences 87 (23), 9421-9425, 1990 | 110 | 1990 |
Shaping up the membrane: diacylglycerol coordinates spatial orientation of signaling M Almena, I Mérida Trends in biochemical sciences 36 (11), 593-603, 2011 | 108 | 2011 |