Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks WG Lewis, LG Green, F Grynszpan, Z Radić, PR Carlier, P Taylor, ... Angewandte Chemie 114 (6), 1095-1099, 2002 | 1131* | 2002 |
Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching WG Lewis, FG Magallon, VV Fokin, MG Finn Journal of the American Chemical Society 126 (30), 9152-9153, 2004 | 508 | 2004 |
Accelerated bioorthogonal conjugation: a practical method for the ligation of diverse functional molecules to a polyvalent virus scaffold SS Gupta, J Kuzelka, P Singh, WG Lewis, M Manchester, MG Finn Bioconjugate chemistry 16 (6), 1572-1579, 2005 | 417 | 2005 |
A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β T Hirota, WG Lewis, AC Liu, JW Lee, PG Schultz, SA Kay Proceedings of the National Academy of Sciences 105 (52), 20746, 2008 | 318 | 2008 |
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly SJ Stray, CR Bourne, S Punna, WG Lewis, MG Finn, A Zlotnick Proceedings of the National Academy of Sciences 102 (23), 8138-8143, 2005 | 308 | 2005 |
High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase T Hirota, JW Lee, WG Lewis, EE Zhang, G Breton, X Liu, M Garcia, ... PLoS biology 8 (12), e1000559, 2010 | 274 | 2010 |
Desorption/ionization on silicon (DIOS) mass spectrometry: background and applications WG Lewis, Z Shen, MG Finn, G Siuzdak International Journal of Mass Spectrometry 226 (1), 107-116, 2003 | 234 | 2003 |
Mammalian circadian signaling networks and therapeutic targets AC Liu, WG Lewis, SA Kay Nature chemical biology 3 (10), 630-639, 2007 | 229 | 2007 |
Host sialoglycans and bacterial sialidases: a mucosal perspective AL Lewis, WG Lewis Cellular microbiology 14 (8), 1174-1182, 2012 | 228 | 2012 |
Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis WG Lewis, LS Robinson, NM Gilbert, JC Perry, AL Lewis Journal of Biological Chemistry 288 (17), 12067-12079, 2013 | 192 | 2013 |
Urinary tract infection as a preventable cause of pregnancy complications: opportunities, challenges, and a global call to action NM Gilbert, VP O'brien, S Hultgren, G Macones, WG Lewis, AL Lewis Global advances in health and medicine 2 (5), 59-69, 2013 | 185 | 2013 |
Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells Q Luo, P Kumar, TJ Vickers, A Sheikh, WG Lewis, DA Rasko, J Sistrunk, ... Infection and immunity 82 (2), 509-521, 2014 | 146 | 2014 |
Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis NM Gilbert, WG Lewis, AL Lewis PloS one 8 (3), e59539, 2013 | 139 | 2013 |
EatA, an immunogenic protective antigen of enterotoxigenic Escherichia coli, degrades intestinal mucin P Kumar, Q Luo, TJ Vickers, A Sheikh, WG Lewis, JM Fleckenstein Infection and immunity 82 (2), 500-508, 2014 | 110 | 2014 |
Immune Activation and Suppression by Group B Streptococcus in a Murine Model of Urinary Tract Infection KA Kline, DJ Schwartz, WG Lewis, SJ Hultgren, AL Lewis Infection and immunity 79 (9), 3588, 2011 | 108 | 2011 |
Hydrolysis of the secreted sialoglycoprotein Immunoglobulin A (IgA) in ex vivo and biochemical models of bacterial vaginosis WG Lewis, LS Robinson, JC Perry, JL Bick, JF Peipert, JE Allsworth, ... Journal of Biological Chemistry, 2011 | 105 | 2011 |
Gardnerella vaginalis and Prevotella bivia Trigger Distinct and Overlapping Phenotypes in a Mouse Model of Bacterial Vaginosis NM Gilbert, WG Lewis, G Li, DK Sojka, JB Lubin, AL Lewis The journal of infectious diseases 220 (7), 1099-1108, 2019 | 95 | 2019 |
Association between obesity and bacterial vaginosis as assessed by Nugent score RT Brookheart, WG Lewis, JF Peipert, AL Lewis, JE Allsworth American journal of obstetrics and gynecology 220 (5), 476. e1-476. e11, 2019 | 80 | 2019 |
The [2+ 2]‐Photocycloaddition of Aromatic Aldehydes and Ketones to 3, 4‐Dihydro‐2‐pyridones: Regioselectivity, Diastereoselectivity, and Reductive Ring Opening of the Product … T Bach, H Bergmann, H Brummerhop, W Lewis, K Harms Chemistry–A European Journal 7 (20), 4512-4521, 2001 | 80 | 2001 |
Associations between the vaginal microbiome and Candida colonization in women of reproductive age BA Tortelli, WG Lewis, JE Allsworth, N Member-Meneh, LR Foster, ... American journal of obstetrics and gynecology 222 (5), 471. e1-471. e9, 2020 | 76 | 2020 |