| Role of axonal transport in neurodegenerative diseases KJ De Vos, AJ Grierson, S Ackerley, CCJ Miller Annu. Rev. Neurosci. 31 (1), 151-173, 2008 | 871 | 2008 |
| Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis L Ferraiuolo, J Kirby, AJ Grierson, M Sendtner, PJ Shaw Nature Reviews Neurology 7 (11), 616-630, 2011 | 696 | 2011 |
| Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ... Human molecular genetics 16 (22), 2720-2728, 2007 | 488 | 2007 |
| The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ... The EMBO journal 35 (15), 1656-1676, 2016 | 444 | 2016 |
| Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz Current Biology 15 (7), 678-683, 2005 | 392 | 2005 |
| Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy CF Valori, K Ning, M Wyles, RJ Mead, AJ Grierson, PJ Shaw, M Azzouz Science translational medicine 2 (35), 35ra42-35ra42, 2010 | 327 | 2010 |
| Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS) LE Cox, L Ferraiuolo, EF Goodall, PR Heath, A Higginbottom, H Mortiboys, ... PloS one 5 (3), e9872, 2010 | 300 | 2010 |
| Charcot–Marie–Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport J Brownlees, S Ackerley, AJ Grierson, NJO Jacobsen, K Shea, ... Human molecular genetics 11 (23), 2837-2844, 2002 | 257 | 2002 |
| Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments S Ackerley, P Thornhill, AJ Grierson, J Brownlees, BH Anderton, PN Leigh, ... The Journal of cell biology 161 (3), 489-495, 2003 | 248 | 2003 |
| Glutamate slows axonal transport of neurofilaments in transfected neurons S Ackerley, AJ Grierson, J Brownlees, P Thornhill, BH Anderton, PN Leigh, ... The Journal of cell biology 150 (1), 165-176, 2000 | 219 | 2000 |
| Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons AR Saha, J Hill, MA Utton, AA Asuni, S Ackerley, AJ Grierson, CC Miller, ... Journal of cell science 117 (7), 1017-1024, 2004 | 218 | 2004 |
| Phosphorylation of thr668 in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress‐activated protein kinase 1b (Jun N‐terminal … CL Standen, J Brownlees, AJ Grierson, S Kesavapany, KF Lau, ... Journal of neurochemistry 76 (1), 316-320, 2001 | 158 | 2001 |
| Hereditary spastic paraparesis: disrupted intracellular transport associated with spastin mutation CJ McDermott, AJ Grierson, JD Wood, M Bingley, SB Wharton, ... Annals of Neurology: Official Journal of the American Neurological …, 2003 | 152 | 2003 |
| Direct evidence for axonal transport defects in a novel mouse model of mutant spastin‐induced hereditary spastic paraplegia (HSP) and human HSP patients PR Kasher, KJ De Vos, SB Wharton, C Manser, EJ Bennett, M Bingley, ... Journal of neurochemistry 110 (1), 34-44, 2009 | 147 | 2009 |
| p38α stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis S Ackerley, AJ Grierson, S Banner, MS Perkinton, J Brownlees, HL Byers, ... Molecular and Cellular Neuroscience 26 (2), 354-364, 2004 | 146 | 2004 |
| Axonal transport of neurofilaments in normal and disease states CCJ Miller, S Ackerley, J Brownlees, AJ Grierson, NJO Jacobsen, ... Cellular and Molecular Life Sciences CMLS 59, 323-330, 2002 | 135 | 2002 |
| The cellular and molecular pathology of the motor system in hereditary spastic paraparesis due to mutation of the spastin gene SB Wharton, CJ McDermott, AJ Grierson, JD Wood, C Gelsthorpe, ... Journal of Neuropathology & Experimental Neurology 62 (11), 1166-1177, 2003 | 120 | 2003 |
| Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS) RJ Mead, EJ Bennett, AJ Kennerley, P Sharp, C Sunyach, P Kasher, ... PloS one 6 (8), e23244, 2011 | 109 | 2011 |
| Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis FM Menzies, AJ Grierson, MR Cookson, PR Heath, J Tomkins, ... Journal of neurochemistry 82 (5), 1118-1128, 2002 | 101 | 2002 |
| Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis SP Allen, S Rajan, L Duffy, H Mortiboys, A Higginbottom, AJ Grierson, ... Neurobiology of Aging 35 (6), 1499-1509, 2014 | 98 | 2014 |
Pamela J ShawProfessor of Neurology, University of Sheffield在 sheffield.ac.uk 的电子邮件经过验证
