The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies WY Mansour, T Rhein, J Dahm-Daphi Nucleic acids research 38 (18), 6065-6077, 2010 | 267 | 2010 |
Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks WY Mansour, S Schumacher, R Rosskopf, T Rhein, F Schmidt-Petersen, ... Nucleic acids research 36 (12), 4088-4098, 2008 | 185 | 2008 |
Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation A Bakr, C Oing, S Köcher, K Borgmann, I Dornreiter, C Petersen, ... Nucleic acids research 43 (6), 3154-3166, 2015 | 142 | 2015 |
A novel hepatitis B virus (HBV) subgenotype D (D8) strain, resulting from recombination between genotypes D and E, is circulating in Niger along with HBV/E strains M Abdou Chekaraou, S Brichler, W Mansour, F Le Gal, A Garba, P Deny, ... Journal of General Virology 91 (6), 1609-1620, 2010 | 117 | 2010 |
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness V Kari, WY Mansour, SK Raul, SJ Baumgart, A Mund, M Grade, H Sirma, ... EMBO reports 17 (11), 1609-1623, 2016 | 112 | 2016 |
Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma WY Mansour, NV Bogdanova, U Kasten-Pisula, T Rieckmann, S Köcher, ... Radiotherapy and oncology 106 (1), 147-154, 2013 | 80 | 2013 |
Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer WY Mansour, P Tennstedt, J Volquardsen, C Oing, M Kluth, C Hube-Magg, ... Scientific reports 8 (1), 3947, 2018 | 70 | 2018 |
The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair U Kasten-Pisula, A Menegakis, I Brammer, K Borgmann, WY Mansour, ... Radiotherapy and oncology 90 (2), 257-264, 2009 | 68 | 2009 |
Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells A Kötter, K Cornils, K Borgmann, J Dahm-Daphi, C Petersen, E Dikomey, ... Molecular oncology 8 (8), 1616-1625, 2014 | 62 | 2014 |
PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response S Wurster, F Hennes, AC Parplys, JI Seelbach, WY Mansour, A Zielinski, ... Oncotarget 7 (9), 9732, 2016 | 56 | 2016 |
The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining WY Mansour, K Borgmann, C Petersen, E Dikomey, J Dahm-Daphi DNA repair 12 (12), 1134-1142, 2013 | 56 | 2013 |
Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase S Koecher, T Rieckmann, G Rohaly, WY Mansour, E Dikomey, I Dornreiter, ... Nucleic Acids Research 40 (17), 8336-8347, 2012 | 56 | 2012 |
Impact of hepatitis B and delta virus co-infection on liver disease in Mauritania: a cross sectional study F Lunel-Fabiani, W Mansour, AO Amar, M Aye, F Le Gal, FZF Malick, ... Journal of Infection 67 (5), 448-457, 2013 | 54 | 2013 |
High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation AC Parplys, JI Seelbach, S Becker, M Behr, A Wrona, C Jend, ... Cell Cycle 14 (19), 3190-3202, 2015 | 48 | 2015 |
The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness V Kari, SK Raul, JM Henck, J Kitz, F Kramer, RL Kosinsky, N Übelmesser, ... Clinical epigenetics 11, 1-13, 2019 | 47 | 2019 |
5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair US Srinivas, J Dyczkowski, T Beißbarth, J Gaedcke, WY Mansour, ... Oncotarget 6 (14), 12574, 2015 | 46 | 2015 |
The impact of remittances on education in Jordan, Syria and Lebanon J Chaaban, W Mansour Economic research forum: Working paper 684 (1), 1-34, 2012 | 42 | 2012 |
5-Azacitidine exerts prolonged pro-apoptotic effects and overcomes cisplatin-resistance in non-seminomatous germ cell tumor cells C Oing, I Verem, WY Mansour, C Bokemeyer, S Dyshlovoy, F Honecker International journal of molecular sciences 20 (1), 21, 2018 | 40 | 2018 |
Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1 A Bakr, S Köcher, J Volquardsen, C Petersen, K Borgmann, E Dikomey, ... Oncotarget 7 (36), 57679, 2016 | 39 | 2016 |
Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer M Toulany, M Iida, S Keinath, FF Iyi, K Mueck, B Fehrenbacher, ... Oncotarget 7 (28), 43746, 2016 | 37 | 2016 |