SLC6 neurotransmitter transporters: structure, function, and regulation AS Kristensen, J Andersen, TN Jørgensen, L Sørensen, J Eriksen, ... Pharmacological reviews 63 (3), 585-640, 2011 | 886 | 2011 |
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ... Nature methods 7 (12), 1003-1008, 2010 | 522 | 2010 |
The binding sites for cocaine and dopamine in the dopamine transporter overlap T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ... Nature neuroscience 11 (7), 780-789, 2008 | 413 | 2008 |
N-terminal truncation of the dopamine transporter abolishes phorbol ester-and substance P receptor-stimulated phosphorylation without impairing transporter internalization C Grånäs, J Ferrer, CJ Loland, JA Javitch, U Gether Journal of Biological Chemistry 278 (7), 4990-5000, 2003 | 214 | 2003 |
Generation of an activating Zn2+ switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the … CJ Loland, L Norregaard, T Litman, U Gether Proceedings of the National Academy of Sciences 99 (3), 1683-1688, 2002 | 162 | 2002 |
Missense dopamine transporter mutations associate with adult parkinsonism and ADHD FH Hansen, T Skjørringe, S Yasmeen, NV Arends, MA Sahai, K Erreger, ... The Journal of clinical investigation 124 (7), 3107-3120, 2014 | 157 | 2014 |
R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse CJ Loland, M Mereu, OM Okunola, J Cao, TE Prisinzano, S Mazier, ... Biological psychiatry 72 (5), 405-413, 2012 | 152 | 2012 |
Defining proximity relationships in the tertiary structure of the dopamine transporter: Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn2+ … CJ Loland, L Norregaard, U Gether Journal of Biological Chemistry 274 (52), 36928-36934, 1999 | 152 | 1999 |
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, AC Kruse, A Manglik, ... Chemistry–A European Journal 18 (31), 9485-9490, 2012 | 149 | 2012 |
An intracellular interaction network regulates conformational transitions in the dopamine transporter J Kniazeff, L Shi, CJ Loland, JA Javitch, H Weinstein, U Gether Journal of Biological Chemistry 283 (25), 17691-17701, 2008 | 147 | 2008 |
Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors CJ Loland, RI Desai, MF Zou, J Cao, P Grundt, K Gerstbrein, HH Sitte, ... Molecular pharmacology 73 (3), 813-823, 2008 | 145 | 2008 |
Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding CJ Loland, C Grånäs, JA Javitch, U Gether Journal of Biological Chemistry 279 (5), 3228-3238, 2004 | 123 | 2004 |
Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions C Bjerggaard, JU Fog, H Hastrup, K Madsen, CJ Loland, JA Javitch, ... Journal of Neuroscience 24 (31), 7024-7036, 2004 | 114 | 2004 |
Regulation of dopamine transporter trafficking by intracellular amphetamine KM Kahlig, BJ Lute, Y Wei, CJ Loland, U Gether, JA Javitch, A Galli Molecular pharmacology 70 (2), 542-548, 2006 | 100 | 2006 |
Tandem facial amphiphiles for membrane protein stabilization PS Chae, K Gotfryd, J Pacyna, LJW Miercke, SGF Rasmussen, ... Journal of the American Chemical Society 132 (47), 16750-16752, 2010 | 98 | 2010 |
Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter P Plenge, L Shi, T Beuming, J Te, AH Newman, H Weinstein, U Gether, ... Journal of Biological Chemistry 287 (47), 39316-39326, 2012 | 94 | 2012 |
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study PS Chae, RR Rana, K Gotfryd, SGF Rasmussen, AC Kruse, KH Cho, ... Chemical communications 49 (23), 2287-2289, 2013 | 85 | 2013 |
Conformational dynamics of the human serotonin transporter during substrate and drug binding IR Möller, M Slivacka, AK Nielsen, SGF Rasmussen, U Gether, CJ Loland, ... Nature communications 10 (1), 1687, 2019 | 68 | 2019 |
The binding sites for benztropines and dopamine in the dopamine transporter overlap H Bisgaard, MAB Larsen, S Mazier, T Beuming, AH Newman, H Weinstein, ... Neuropharmacology 60 (1), 182-190, 2011 | 67 | 2011 |
Novel and high affinity 2-[(diphenylmethyl) sulfinyl] acetamide (modafinil) analogues as atypical dopamine transporter inhibitors J Cao, RD Slack, OM Bakare, C Burzynski, R Rais, BS Slusher, T Kopajtic, ... Journal of medicinal chemistry 59 (23), 10676-10691, 2016 | 65 | 2016 |