Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants SCJ Parker, ML Stitzel, DL Taylor, JM Orozco, MR Erdos, JA Akiyama, ... Proceedings of the National Academy of Sciences 110 (44), 17921-17926, 2013 | 723* | 2013 |
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes A Varshney, LJ Scott, RP Welch, MR Erdos, PS Chines, N Narisu, ... Proceedings of the National Academy of Sciences 114 (9), 2301-2306, 2017 | 202 | 2017 |
The genetic regulatory signature of type 2 diabetes in human skeletal muscle LJ Scott, MR Erdos, JR Huyghe, RP Welch, AT Beck, BN Wolford, ... Nature communications 7 (1), 11764, 2016 | 133 | 2016 |
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle DL Taylor, AU Jackson, N Narisu, G Hemani, MR Erdos, PS Chines, ... Proceedings of the National Academy of Sciences 116 (22), 10883-10888, 2019 | 124 | 2019 |
BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues LS Zou, MR Erdos, DL Taylor, PS Chines, A Varshney, ... BMC genomics 19, 1-15, 2018 | 43 | 2018 |
Interactions between genetic variation and cellular environment in skeletal muscle gene expression DL Taylor, DA Knowles, LJ Scott, AH Ramirez, FP Casale, BN Wolford, ... PLoS One 13 (4), e0195788, 2018 | 21 | 2018 |
Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis HJ Taylor, YH Hung, N Narisu, MR Erdos, M Kanke, T Yan, CM Grenko, ... Proceedings of the National Academy of Sciences 120 (7), e2206797120, 2023 | 20 | 2023 |
Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population A Sethi, DL Taylor, JG Ruby, J Venkataraman, E Sorokin, M Cule, ... Frontiers in Cardiovascular Medicine 9, 1003246, 2022 | 16* | 2022 |
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ... Cell Metabolism 35 (11), 1897-1914. e11, 2023 | 10 | 2023 |
The promise and reality of therapeutic discovery from large cohorts E Melamud, DL Taylor, A Sethi, M Cule, A Baryshnikova, D Saleheen, ... The Journal of Clinical Investigation 130 (2), 575-581, 2020 | 9 | 2020 |
Bacterial Logic Devices Reveal Unexpected Behavior of Frameshift Suppressor tRNAs EM Sawyer, C Barta, R Clemente, M Conn, C Davis, C Doyle, M Gearing, ... Interdisciplinary Bio Central 4 (10), 2012 | 5 | 2012 |
Illuminating the Black Box of Genome Sequence Assembly: A Free Online Tool to Introduce Students to Bioinformatics DL Taylor, AM Campbell, LJ Heyer The American Biology Teacher 75 (8), 572-577, 2013 | 3 | 2013 |
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals Z Zhao, RDO Albanus, H Taylor, X Tang, Y Han, P Orchard, A Varshney, ... Research Square, 2023 | 2 | 2023 |
Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits S Hudaiberdiev, DL Taylor, W Song, N Narisu, RM Bhuiyan, HJ Taylor, ... Proceedings of the National Academy of Sciences 120 (35), e2206612120, 2023 | 2 | 2023 |
Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours CM Grenko, LL Bonnycastle, HJ Taylor, T Yan, AJ Swift, CC Robertson, ... bioRxiv, 2023 | 1 | 2023 |
Single-cell RNA sequencing reveals dysregulated cellular programmes in the inflamed epithelium of Crohn's disease patients. M Krzak, T Alegbe, DL Taylor, MH Ghouraba, M Strickland, R Satti, ... medRxiv, 2023.09. 06.23295056, 2023 | | 2023 |