Cancer stem cells: impact, heterogeneity, and uncertainty JA Magee, E Piskounova, SJ Morrison Cancer cell 21 (3), 283-296, 2012 | 1386 | 2012 |
Oxidative stress inhibits distant metastasis by human melanoma cells E Piskounova, M Agathocleous, MM Murphy, Z Hu, SE Huddlestun, ... Nature 527 (7577), 186-191, 2015 | 1169 | 2015 |
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms E Piskounova, C Polytarchou, JE Thornton, RJ LaPierre, C Pothoulakis, ... Cell 147 (5), 1066-1079, 2011 | 719 | 2011 |
Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells JP Hagan, E Piskounova, RI Gregory Nature structural & molecular biology 16 (10), 1021-1025, 2009 | 594 | 2009 |
Ascorbate regulates haematopoietic stem cell function and leukaemogenesis M Agathocleous, CE Meacham, RJ Burgess, E Piskounova, Z Zhao, ... Nature 549 (7673), 476-481, 2017 | 502 | 2017 |
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28 E Piskounova, SR Viswanathan, M Janas, RJ LaPierre, GQ Daley, P Sliz, ... Journal of Biological Chemistry 283 (31), 21310-21314, 2008 | 425 | 2008 |
Cancer, oxidative stress, and metastasis JG Gill, E Piskounova, SJ Morrison Cold Spring Harbor symposia on quantitative biology 81, 163-175, 2016 | 291 | 2016 |
Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7) JE Thornton, HM Chang, E Piskounova, RI Gregory Rna 18 (10), 1875-1885, 2012 | 250 | 2012 |
Human melanoma metastasis in NSG mice correlates with clinical outcome in patients E Quintana, E Piskounova, M Shackleton, D Weinberg, U Eskiocak, ... Science translational medicine 4 (159), 159ra149-159ra149, 2012 | 122 | 2012 |
An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants MP Zafra, MJ Parsons, J Kim, D Alonso-Curbelo, S Goswami, EM Schatoff, ... Cancer discovery 10 (11), 1654-1671, 2020 | 94 | 2020 |
Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty AP Silveira-Neto, LF Leal, AB Emerman, KD Henderson, E Piskounova, ... Hormone research in paediatrics 78 (3), 144-150, 2012 | 44 | 2012 |
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage S Jun, S Mahesula, TP Mathews, MS Martin-Sandoval, Z Zhao, ... Cell metabolism 33 (9), 1777-1792. e8, 2021 | 42 | 2021 |
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... Science signaling 15 (757), eabm0808, 2022 | 40 | 2022 |
SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2 TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... | 39 | 2020 |
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... BioRxiv, 2020.08. 14.251207, 2020 | 34 | 2020 |
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma T Schild, MR McReynolds, C Shea, V Low, BE Schaffer, JM Asara, ... Cell Reports 35 (11), 2021 | 24 | 2021 |
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation MM Drozdz, AS Doane, R Alkallas, G Desman, R Bareja, M Reilly, J Bang, ... Cell reports 40 (13), 2022 | 5 | 2022 |
Combination treatments for melanoma S Morrison, E Piskounova, U Eskiocak US Patent 9,561,245, 2017 | 4 | 2017 |
Lin28-mediated control of let-7 biogenesis RI Gregory, E Piskounova, D Iliopoulos US Patent 9,938,354, 2018 | 3 | 2018 |
Oxidative stress limits metastasis of human melanoma cells E Piskounova, M Agathocleous, M Murphy, Z Hu, R DeBerardinis, ... Cancer Research 76 (14_Supplement), 2806-2806, 2016 | 2 | 2016 |