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Michael A Erb
Michael A Erb
在 scripps.edu 的电子邮件经过验证
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引用次数
引用次数
年份
The dTAG system for immediate and target-specific protein degradation
B Nabet, JM Roberts, DL Buckley, J Paulk, S Dastjerdi, A Yang, ...
Nature chemical biology 14 (5), 431-441, 2018
7932018
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation
CM Olson, B Jiang, MA Erb, Y Liang, ZM Doctor, Z Zhang, T Zhang, ...
Nature chemical biology 14 (2), 163-170, 2018
4612018
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment
GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ...
Molecular cell 67 (1), 5-18. e19, 2017
4142017
Transcription control by the ENL YEATS domain in acute leukaemia
MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ...
Nature 543 (7644), 270-274, 2017
3132017
ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
L Wan, H Wen, Y Li, J Lyu, Y Xi, T Hoshii, JK Joseph, X Wang, YHE Loh, ...
Nature 543 (7644), 265-269, 2017
2542017
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands
LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ...
Nature chemical biology 14 (4), 405-412, 2018
2232018
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
R Zeid, MA Lawlor, E Poon, JM Reyes, M Fulciniti, MA Lopez, TG Scott, ...
Nature genetics 50 (4), 515-523, 2018
2072018
Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders
M Ishoey, S Chorn, N Singh, MG Jaeger, M Brand, J Paulk, S Bauer, ...
ACS chemical biology 13 (3), 553-560, 2018
1582018
Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia
L Garnar-Wortzel, TR Bishop, S Kitamura, N Milosevich, JN Asiaban, ...
ACS central science 7 (5), 815-830, 2021
582021
A short ORF-encoded transcriptional regulator
M Koh, I Ahmad, Y Ko, Y Zhang, TF Martinez, JK Diedrich, Q Chu, ...
Proceedings of the National Academy of Sciences 118 (4), e2021943118, 2021
422021
Cell-based ligand discovery for the ENL YEATS domain
JN Asiaban, N Milosevich, E Chen, TR Bishop, J Wang, Y Zhang, ...
ACS Chemical Biology 15 (4), 895-903, 2020
382020
Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1
TR Daniels-Wells, G Helguera, JA Rodríguez, LS Leoh, MA Erb, ...
Toxicology in Vitro 27 (1), 220-231, 2013
362013
Pharmacological Modulation of Transcriptional Coregulators in Cancer
TR Bishop, Y Zhang, MA Erb
Trends in pharmacological sciences 40 (6), 388-402, 2019
152019
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
Y Zhang, D Remillard, U Onubogu, B Karakyriakou, JN Asiaban, ...
Nature Structural & Molecular Biology 30 (8), 1160-1171, 2023
122023
Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition
TR Bishop, C Subramanian, EM Bilotta, L Garnar-Wortzel, AR Ramos, ...
Nature Chemical Biology 19 (10), 1215-1222, 2023
112023
Enabling cancer target validation with genetically encoded systems for ligand-induced protein degradation
Y Zhang, MA Erb
Current Research in Chemical Biology 1, 100011, 2021
62021
Inherited blood cancer predisposition through altered transcription elongation
J Zhao, LD Cato, UP Arora, EL Bao, SC Bryant, N Williams, Y Jia, ...
Cell 187 (3), 642-658. e19, 2024
42024
Redirecting the pioneering function of FOXA1 with covalent small molecules
SJ Won, Y Zhang, CJ Reinhardt, NS MacRae, KE DeMeester, E Njomen, ...
bioRxiv, 2024.03. 21.586158, 2024
42024
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
Y Zhang, D Remillard, U Onubogu, B Karakyriakou, JN Asiaban, ...
bioRxiv, 2022
42022
Small-molecule tools for YEATS domain proteins
MA Erb
Current Opinion in Chemical Biology 77, 102404, 2023
22023
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