Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes JA Todd, NM Walker, JD Cooper, DJ Smyth, K Downes, V Plagnol, ... Nature genetics 39 (7), 857-864, 2007 | 1660 | 2007 |
Lineage-specific genome architecture links enhancers and non-coding disease variants to target gene promoters BM Javierre, OS Burren, SP Wilder, R Kreuzhuber, SM Hill, S Sewitz, ... Cell 167 (5), 1369-1384. e19, 2016 | 994 | 2016 |
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls Nature 464 (7289), 713-720, 2010 | 936 | 2010 |
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region DJ Smyth, JD Cooper, R Bailey, S Field, O Burren, LJ Smink, C Guja, ... Nature genetics 38 (6), 617-619, 2006 | 793 | 2006 |
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers S Onengut-Gumuscu, WM Chen, O Burren, NJ Cooper, AR Quinlan, ... Nature genetics 47 (4), 381-386, 2015 | 689 | 2015 |
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ... Cell 167 (5), 1145-1149, 2016 | 524 | 2016 |
Widespread seasonal gene expression reveals annual differences in human immunity and physiology XC Dopico, M Evangelou, RC Ferreira, H Guo, ML Pekalski, DJ Smyth, ... Nature communications 6 (1), 7000, 2015 | 504 | 2015 |
Whole-genome sequencing of patients with rare diseases in a national health system E Turro, WJ Astle, K Megy, S Gräf, D Greene, O Shamardina, HL Allen, ... Nature 583 (7814), 96-102, 2020 | 420 | 2020 |
Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes JD Cooper, DJ Smyth, NM Walker, H Stevens, OS Burren, C Wallace, ... Diabetes 60 (5), 1624-1631, 2011 | 387 | 2011 |
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes RC Ferreira, H Guo, RMR Coulson, DJ Smyth, ML Pekalski, OS Burren, ... Diabetes 63 (7), 2538-2550, 2014 | 310 | 2014 |
Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource CA Dendrou, V Plagnol, E Fung, JHM Yang, K Downes, JD Cooper, ... Nature genetics 41 (9), 1011-1015, 2009 | 308 | 2009 |
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability KA Hunt, V Mistry, NA Bockett, T Ahmad, M Ban, JN Barker, JC Barrett, ... Nature 498 (7453), 232-235, 2013 | 249 | 2013 |
Whole-genome sequencing of a sporadic primary immunodeficiency cohort JED Thaventhiran, H Lango Allen, OS Burren, W Rae, D Greene, ... Nature 583 (7814), 90-95, 2020 | 185 | 2020 |
Seven newly identified loci for autoimmune thyroid disease JD Cooper, MJ Simmonds, NM Walker, O Burren, OJ Brand, H Guo, ... Human molecular genetics 21 (23), 5202-5208, 2012 | 185 | 2012 |
Plasma proteomic associations with genetics and health in the UK Biobank BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... Nature 622 (7982), 329-338, 2023 | 181 | 2023 |
Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls MD Fortune, H Guo, O Burren, E Schofield, NM Walker, M Ban, SJ Sawcer, ... Nature genetics 47 (7), 839-846, 2015 | 162 | 2015 |
Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases H Guo, MD Fortune, OS Burren, E Schofield, JA Todd, C Wallace Human molecular genetics 24 (12), 3305-3313, 2015 | 149 | 2015 |
Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene LJ Davison, C Wallace, JD Cooper, NF Cope, NK Wilson, DJ Smyth, ... Human molecular genetics 21 (2), 322-333, 2012 | 129 | 2012 |
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research OS Burren, EC Adlem, P Achuthan, M Christensen, RMR Coulson, ... Nucleic acids research 39 (suppl_1), D997-D1001, 2010 | 106 | 2010 |
Genetics of Type 1 Diabetes in Finland, Simmonds MJ, Heward JM, Gough SC, Wellcome Trust Case Control Consortium, Dunger DB, Wicker LS, Clayton DG: Robust associations of four … JA Todd, NM Walker, JD Cooper, DJ Smyth, K Downes, V Plagnol, ... Nat Genet 39 (7), 857-864, 2007 | 105 | 2007 |