Discovery of 1-[2-(2, 4-dimethylphenylsulfanyl) phenyl] piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder B Bang-Andersen, T Ruhland, M Jørgensen, G Smith, K Frederiksen, ... Journal of medicinal chemistry 54 (9), 3206-3221, 2011 | 525 | 2011 |
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder A Mørk, A Pehrson, LT Brennum, SM Nielsen, H Zhong, AB Lassen, ... Journal of Pharmacology and Experimental Therapeutics 340 (3), 666-675, 2012 | 355 | 2012 |
Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs E Dale, B Bang-Andersen, C Sánchez Biochemical pharmacology 95 (2), 81-97, 2015 | 293 | 2015 |
Palladium‐Catalyzed Aryl Amination–Heck Cyclization Cascade: A One‐Flask Approach to 3‐Substituted Indoles T Jensen, H Pedersen, B Bang‐Andersen, R Madsen, M Jørgensen Angewandte Chemie International Edition 47 (5), 888-890, 2008 | 185 | 2008 |
Palladium‐Catalyzed Three‐Component Approach to Promazine with Formation of One Carbon–Sulfur and Two Carbon–Nitrogen Bonds T Dahl, CW Tornøe, B Bang‐Andersen, P Nielsen, M Jørgensen Angewandte Chemie International Edition 47 (9), 1726-1728, 2008 | 148 | 2008 |
Identification of the cytochrome P450 and other enzymes involved in the in vitro oxidative metabolism of a novel antidepressant, Lu AA21004 MG Hvenegaard, B Bang-Andersen, H Pedersen, M Jørgensen, A Püschl, ... Drug Metabolism and Disposition 40 (7), 1357-1365, 2012 | 132 | 2012 |
Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats J Arnt, B Bang-Andersen, B Grayson, FP Bymaster, MP Cohen, ... International Journal of Neuropsychopharmacology 13 (8), 1021-1033, 2010 | 132 | 2010 |
Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters J Andersen, AS Kristensen, B Bang-Andersen, K Strømgaard Chemical communications, 3677-3692, 2009 | 118 | 2009 |
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ... Journal of Biological Chemistry 285 (3), 2051-2063, 2010 | 109 | 2010 |
Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT6 and 5-HT2A receptor mechanisms N Idris, J Neill, B Grayson, B Bang-Andersen, LM Witten, LT Brennum, ... Psychopharmacology 208, 23-36, 2010 | 99 | 2010 |
Direct trans-Selective Ruthenium-Catalyzed Reduction of Alkynes in Two-Chamber Reactors and Continuous Flow KT Neumann, S Klimczyk, MN Burhardt, B Bang-Andersen, T Skrydstrup, ... ACS Catalysis 6 (7), 4710-4714, 2016 | 85 | 2016 |
Application of cross-species PET imaging to assess neurotransmitter release in brain SJ Finnema, M Scheinin, M Shahid, J Lehto, E Borroni, B Bang-Andersen, ... Psychopharmacology 232, 4129-4157, 2015 | 84 | 2015 |
Palladium-catalyzed carbonylative sonogashira coupling of aryl bromides using near stoichiometric carbon monoxide KT Neumann, SR Laursen, AT Lindhardt, B Bang-Andersen, T Skrydstrup Organic letters 16 (8), 2216-2219, 2014 | 83 | 2014 |
Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters J Andersen, N Stuhr-Hansen, L Zachariassen, S Toubro, SMR Hansen, ... Proceedings of the National Academy of Sciences 108 (29), 12137-12142, 2011 | 73 | 2011 |
From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: Synthesis and structure− activity relationship studies JNN Eildal, J Andersen, AS Kristensen, AM Jørgensen, B Bang-Andersen, ... Journal of medicinal chemistry 51 (10), 3045-3048, 2008 | 69 | 2008 |
Phenyl-piperazine derivatives as serotonin reuptake inhibitors T Ruhland, GP Smith, B Bang-Andersen, A Puschl, EK Moltzen, ... US Patent 7,138,407, 2006 | 69 | 2006 |
5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists C Madsen, AA Jensen, T Liljefors, U Kristiansen, B Nielsen, CP Hansen, ... Journal of medicinal chemistry 50 (17), 4147-4161, 2007 | 62 | 2007 |
A novel series of (phenoxyalkyl) imidazoles as potent H3-receptor histamine antagonists CR Ganellin, A Fkyerat, B Bang-Andersen, S Athmani, W Tertiuk, ... Journal of medicinal chemistry 39 (19), 3806-3813, 1996 | 60 | 1996 |
Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century-a medicinal chemistry survey EK Moltzen, B Bang-Andersen Current topics in medicinal chemistry 6 (17), 1801-1823, 2006 | 58 | 2006 |
Heteroaryl analogues of AMPA. Synthesis and quantitative structure− activity relationships B Bang-Andersen, SM Lenz, N Skjærbæk, KK Søby, HO Hansen, B Ebert, ... Journal of medicinal chemistry 40 (18), 2831-2842, 1997 | 58 | 1997 |