Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 11104 | 2021 |
Targeting autophagy in cancer JMM Levy, CG Towers, A Thorburn Nature Reviews Cancer 17 (9), 528-542, 2017 | 2389 | 2017 |
Therapeutic targeting of autophagy CG Towers, A Thorburn EBioMedicine 14, 15-23, 2016 | 300 | 2016 |
Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover BE Fitzwalter, CG Towers, KD Sullivan, Z Andrysik, M Hoh, M Ludwig, ... Developmental cell 44 (5), 555-565. e3, 2018 | 198 | 2018 |
Autophagy and cancer: Modulation of cell death pathways and cancer cell adaptations CG Towers, D Wodetzki, A Thorburn Journal of Cell Biology 219 (1), e201909033, 2019 | 142 | 2019 |
The SIX1-EYA transcriptional complex as a therapeutic target in cancer MA Blevins, CG Towers, AN Patrick, R Zhao, HL Ford Expert opinion on therapeutic targets 19 (2), 213-225, 2015 | 113 | 2015 |
Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy CG Towers, DK Wodetzki, J Thorburn, KR Smith, MC Caino, A Thorburn Developmental cell 56 (14), 2029-2042. e5, 2021 | 99 | 2021 |
Cancer cells upregulate NRF2 signaling to adapt to autophagy inhibition CG Towers, BE Fitzwalter, D Regan, A Goodspeed, MJ Morgan, CW Liu, ... Developmental cell 50 (6), 690-703. e6, 2019 | 90 | 2019 |
ZZ-dependent regulation of p62/SQSTM1 in autophagy Y Zhang, SR Mun, JF Linares, JW Ahn, CG Towers, CH Ji, BE Fitzwalter, ... Nature communications 9 (1), 4373, 2018 | 88 | 2018 |
Targeting the lysosome for cancer therapy CG Towers, A Thorburn Cancer discovery 7 (11), 1218-1220, 2017 | 64 | 2017 |
The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L AL Guarnieri, CG Towers, DJ Drasin, MUJ Oliphant, Z Andrysik, TJ Hotz, ... Oncogene 37 (28), 3879-3893, 2018 | 60 | 2018 |
The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p CG Towers, AL Guarnieri, DS Micalizzi, JC Harrell, AE Gillen, J Kim, ... Nature communications 6 (1), 10077, 2015 | 50 | 2015 |
Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal LE Newman, S Weiser Novak, GR Rojas, N Tadepalle, CR Schiavon, ... Nature Cell Biology 26 (2), 194-206, 2024 | 23 | 2024 |
Estrogen regulation of mTOR signaling and mitochondrial function in invasive lobular carcinoma cell lines requires WNT4 MT Shackleford, DM Rao, EK Bordeaux, HM Hicks, CG Towers, JL Sottnik, ... Cancers 12 (10), 2931, 2020 | 23 | 2020 |
Mechanistic insight into the regulation of SQSTM1/p62 Y Zhang, SR Mun, JF Linares, CG Towers, A Thorburn, MT Diaz-Meco, ... Autophagy 15 (4), 735-737, 2019 | 18 | 2019 |
Beyond mitophagy: mitochondrial-derived vesicles can get the job done! P Mondal, C Towers Autophagy 18 (2), 449-451, 2022 | 13 | 2022 |
Autophagy-dependent cancer cells circumvent loss of the upstream regulator RB1CC1/FIP200 and loss of LC3 conjugation by similar mechanisms CG Towers, D Wodetzki, A Thorburn Autophagy 16 (7), 1332-1340, 2020 | 13 | 2020 |
A genome-wide loss-of-function screen identifies SLC26A2 as a novel mediator of TRAIL resistance LY Dimberg, CG Towers, K Behbakht, TJ Hotz, J Kim, S Fosmire, ... Molecular Cancer Research 15 (4), 382-394, 2017 | 10 | 2017 |
Recent advances in the role of autophagy in endocrine-dependent tumors A Komarla, S Dufresne, CG Towers Endocrine Reviews 44 (4), 629-646, 2023 | 7 | 2023 |
Enhancing anti-tumor immunity by autophagy inhibition A Thorburn, CG Towers Nature Cancer 2 (5), 484-486, 2021 | 7 | 2021 |