Mechanism of activation of protein kinase JAK2 by the growth hormone receptor AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ... Science 344 (6185), 1249783, 2014 | 441 | 2014 |
ABC transporters: a riddle wrapped in a mystery inside an enigma PM Jones, ML O’Mara, AM George Trends in biochemical sciences 34 (10), 520-531, 2009 | 242 | 2009 |
ATP-binding cassette transporters in Escherichia coli A Moussatova, C Kandt, ML O'Mara, DP Tieleman Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (9), 1757-1771, 2008 | 235 | 2008 |
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias W Chen, R Wang, B Chen, X Zhong, H Kong, Y Bai, Q Zhou, C Xie, ... Nature medicine 20 (2), 184-192, 2014 | 206 | 2014 |
The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter E Procko, ML O'Mara, WFD Bennett, DP Tieleman, R Gaudet The FASEB Journal 23 (5), 1287-1302, 2009 | 199 | 2009 |
Imperfect coordination chemistry facilitates metal ion release in the Psa permease RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ... Nature chemical biology 10 (1), 35-41, 2014 | 154 | 2014 |
Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding A Anandan, GL Evans, K Condic-Jurkic, ML O’Mara, CM John, NJ Phillips, ... Proceedings of the National Academy of Sciences 114 (9), 2218-2223, 2017 | 132 | 2017 |
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae SL Begg, BA Eijkelkamp, Z Luo, RM Counago, JR Morey, MJ Maher, ... Nature communications 6 (1), 6418, 2015 | 126 | 2015 |
Structural arrangement of the transmission interface in the antigen ABC transport complex TAP G Oancea, ML O'Mara, WFD Bennett, DP Tieleman, R Abele, R Tampé Proceedings of the National Academy of Sciences 106 (14), 5551-5556, 2009 | 125 | 2009 |
Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA JA Kretzmann, D Ho, CW Evans, JHC Plani-Lam, B Garcia-Bloj, ... Chemical science 8 (4), 2923-2930, 2017 | 124 | 2017 |
P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK ML O’Mara, DP Tieleman Febs Letters 581 (22), 4217-4222, 2007 | 118 | 2007 |
AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae CD Plumptre, BA Eijkelkamp, JR Morey, F Behr, RM Couñago, ... Molecular microbiology 91 (4), 834-851, 2014 | 107 | 2014 |
Conduction mechanisms of chloride ions in ClC-type channels B Corry, M O’Mara, SH Chung Biophysical journal 86 (2), 846-860, 2004 | 81 | 2004 |
Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1 SJ Fairweather, A Bröer, ML O'Mara, S Bröer Biochemical Journal 446 (1), 135-148, 2012 | 73 | 2012 |
Homology model of the GABAA receptor examined using Brownian dynamics M O’Mara, B Cromer, M Parker, SH Chung Biophysical Journal 88 (5), 3286-3299, 2005 | 73 | 2005 |
The effect of environment on the structure of a membrane protein: P-glycoprotein under physiological conditions ML O’Mara, AE Mark Journal of Chemical Theory and Computation 8 (10), 3964-3976, 2012 | 61 | 2012 |
Simple design of an enzyme-inspired supported catalyst based on a catalytic triad MD Nothling, A Ganesan, K Condic-Jurkic, E Pressly, A Davalos, ... Chem 2 (5), 732-745, 2017 | 57 | 2017 |
Vancomycin: ligand recognition, dimerization and super‐complex formation ZG Jia, ML O'Mara, J Zuegg, MA Cooper, AE Mark The FEBS journal 280 (5), 1294-1307, 2013 | 55 | 2013 |
Structural and dynamic perspectives on the promiscuous transport activity of P-glycoprotein N Subramanian, K Condic-Jurkic, ML O’Mara Neurochemistry international 98, 146-152, 2016 | 49 | 2016 |
Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin SJ Fairweather, A Bröer, N Subramanian, E Tumer, Q Cheng, D Schmoll, ... Journal of Biological Chemistry 290 (40), 24308-24325, 2015 | 49 | 2015 |