Leptin and insulin act on POMC neurons to promote the browning of white fat GT Dodd, S Decherf, K Loh, SE Simonds, F Wiede, E Balland, TL Merry, ... Cell 160 (1), 88-104, 2015 | 431 | 2015 |
Obesity drives STAT-1-dependent NASH and STAT-3-dependent HCC M Grohmann, F Wiede, GT Dodd, EN Gurzov, GJ Ooi, T Butt, ... Cell 175 (5), 1289-1306. e20, 2018 | 342 | 2018 |
Age-related decline in primary CD8+ T cell responses is associated with the development of senescence in virtual memory CD8+ T cells KM Quinn, A Fox, KL Harland, BE Russ, J Li, THO Nguyen, L Loh, ... Cell reports 23 (12), 3512-3524, 2018 | 238 | 2018 |
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice F Wiede, BJ Shields, SH Chew, K Kyparissoudis, C Van Vliet, S Galic, ... The Journal of clinical investigation 121 (12), 4758-4774, 2011 | 238 | 2011 |
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance K Loh, A Fukushima, X Zhang, S Galic, D Briggs, PJ Enriori, S Simonds, ... Cell metabolism 14 (5), 684-699, 2011 | 205 | 2011 |
Cognitive dysfunction in mice deficient for TNF‐and its receptors BT Baune, F Wiede, A Braun, J Golledge, V Arolt, H Koerner American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147 …, 2008 | 200 | 2008 |
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex DX Beringer, FS Kleijwegt, F Wiede, AR Van Der Slik, KL Loh, J Petersen, ... Nature immunology 16 (11), 1153-1161, 2015 | 152 | 2015 |
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers BJ Shields, F Wiede, EN Gurzov, K Wee, C Hauser, HJ Zhu, TJ Molloy, ... Molecular and cellular biology 33 (3), 557-570, 2013 | 127 | 2013 |
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1 J Le Nours, NA Gherardin, SH Ramarathinam, W Awad, F Wiede, ... Science 366 (6472), 1522-1527, 2019 | 121 | 2019 |
PTPN 2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours F Wiede, KH Lu, X Du, S Liang, K Hochheiser, GT Dodd, PK Goh, ... The EMBO journal 39 (2), e103637, 2020 | 108 | 2020 |
T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis A Fukushima, K Loh, S Galic, B Fam, B Shields, F Wiede, ML Tremblay, ... diabetes 59 (8), 1906-1914, 2010 | 94 | 2010 |
Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response S Gras, J Chadderton, CM Del Campo, C Farenc, F Wiede, TM Josephs, ... Immunity 45 (4), 749-760, 2016 | 91 | 2016 |
PTP1B is an intracellular checkpoint that limits T-cell and CAR T-cell antitumor immunity F Wiede, KH Lu, X Du, MN Zeissig, R Xu, PK Goh, CE Xirouchaki, ... Cancer discovery 12 (3), 752-773, 2022 | 83 | 2022 |
High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage TL Merry, M Tran, M Stathopoulos, F Wiede, BC Fam, GT Dodd, I Clarke, ... Antioxidants & redox signaling 20 (14), 2114-2129, 2014 | 75 | 2014 |
Induction of novel cytokines and chemokines by advanced glycation endproducts determined with a cytometric bead array K Berbaum, K Shanmugam, G Stuchbury, F Wiede, H Körner, G Münch Cytokine 41 (3), 198-203, 2008 | 74 | 2008 |
PTPN2 attenuates T-cell lymphopenia-induced proliferation F Wiede, NL La Gruta, T Tiganis Nature communications 5 (1), 3073, 2014 | 69 | 2014 |
PTPN2-deficiency exacerbates T follicular helper cell and B cell responses and promotes the development of autoimmunity F Wiede, F Sacirbegovic, YA Leong, D Yu, T Tiganis Journal of autoimmunity 76, 85-100, 2017 | 68 | 2017 |
Analysis of the CCR7 expression on murine bone marrow-derived and spleen dendritic cells U Ritter, F Wiede, D Mielenz, Z Kiafard, J Zwirner, H Körner Journal of leukocyte biology 76 (2), 472-476, 2004 | 66 | 2004 |
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity MND Svensson, KM Doody, BJ Schmiedel, S Bhattacharyya, B Panwar, ... The Journal of Clinical Investigation 129 (3), 1193-1210, 2019 | 59 | 2019 |
CCR6 is transiently upregulated on B cells after activation and modulates the germinal center reaction in the mouse F Wiede, PD Fromm, I Comerford, E Kara, J Bannan, W Schuh, ... Immunology and cell biology 91 (5), 335-339, 2013 | 52 | 2013 |