Coactivator condensation at super-enhancers links phase separation and gene control BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... Science 361 (6400), eaar3958, 2018 | 1947 | 2018 |
Transcription factors activate genes through the phase-separation capacity of their activation domains A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ... Cell 175 (7), 1842-1855. e16, 2018 | 1402 | 2018 |
Metabolic regulation of gene expression through histone acylations BR Sabari, D Zhang, CD Allis, Y Zhao Nature reviews Molecular cell biology 18 (2), 90-101, 2017 | 832 | 2017 |
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates YE Guo, JC Manteiga, JE Henninger, BR Sabari, A Dall’Agnese, ... Nature 572 (7770), 543-548, 2019 | 530 | 2019 |
Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation BR Sabari, Z Tang, H Huang, V Yong-Gonzalez, H Molina, HE Kong, ... Molecular cell 58 (2), 203-215, 2015 | 523 | 2015 |
SnapShot: histone modifications H Huang, BR Sabari, BA Garcia, CD Allis, Y Zhao Cell 159 (2), 458-458. e1, 2014 | 449 | 2014 |
Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark L Dai, C Peng, E Montellier, Z Lu, Y Chen, H Ishii, A Debernardi, ... Nature chemical biology 10 (5), 365-370, 2014 | 410 | 2014 |
Partitioning of cancer therapeutics in nuclear condensates IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Science 368 (6497), 1386-1392, 2020 | 339 | 2020 |
Enhancer features that drive formation of transcriptional condensates K Shrinivas, BR Sabari, EL Coffey, IA Klein, A Boija, AV Zamudio, ... Molecular cell 75 (3), 549-561. e7, 2019 | 333 | 2019 |
Molecular coupling of histone crotonylation and active transcription by AF9 YEATS domain Y Li, BR Sabari, T Panchenko, H Wen, D Zhao, H Guan, L Wan, H Huang, ... Molecular cell 62 (2), 181-193, 2016 | 326 | 2016 |
Biomolecular condensates in the nucleus BR Sabari, A Dall’Agnese, RA Young Trends in biochemical sciences 45 (11), 961-977, 2020 | 312 | 2020 |
Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular cell 76 (5), 753-766. e6, 2019 | 209 | 2019 |
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas J Bayliss, P Mukherjee, C Lu, SU Jain, C Chung, D Martinez, B Sabari, ... Science translational medicine 8 (366), 366ra161-366ra161, 2016 | 177 | 2016 |
Functional partitioning of transcriptional regulators by patterned charge blocks H Lyons, RT Veettil, P Pradhan, C Fornero, N De La Cruz, K Ito, M Eppert, ... Cell 186 (2), 327-345. e28, 2023 | 107 | 2023 |
Biomolecular condensates and gene activation in development and disease BR Sabari Developmental cell 55 (1), 84-96, 2020 | 49 | 2020 |
Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells FR Melo, O Wallerman, A Paivandy, G Calounova, AM Gustafson, ... Journal of Allergy and Clinical Immunology 140 (2), 474-485, 2017 | 47 | 2017 |
Is transcriptional regulation just going through a phase? GJ Narlikar, S Myong, D Larson, K Maeshima, N Francis, K Rippe, ... Molecular cell 81 (8), 1579-1585, 2021 | 34 | 2021 |
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ... Science translational medicine 13 (614), eabc0497, 2021 | 30 | 2021 |
Phase separation in biology and disease; current perspectives and open questions S Boeynaems, S Chong, J Gsponer, L Holt, D Milovanovic, DM Mitrea, ... Journal of molecular biology 435 (5), 167971, 2023 | 24 | 2023 |
Coactivator condensation drives cardiovascular cell lineage specification P Gan, M Eppert, N De La Cruz, H Lyons, AM Shah, RT Veettil, K Chen, ... Science Advances 10 (11), eadk7160, 2024 | 1 | 2024 |