FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 1291 | 2023 |
Common genetic variation drives molecular heterogeneity in human iPSCs H Kilpinen, A Goncalves, A Leha, V Afzal, K Alasoo, S Ashford, S Bala, ... Nature 546 (7658), 370-375, 2017 | 606 | 2017 |
FinnGen: Unique genetic insights from combining isolated population and national health register data MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, K Donner, ... medrxiv, 2022.03. 03.22271360, 2022 | 412 | 2022 |
Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response K Alasoo, J Rodrigues, S Mukhopadhyay, AJ Knights, AL Mann, K Kundu, ... Nature genetics, 1, 2018 | 297 | 2018 |
A compendium of uniformly processed human gene expression and splicing quantitative trait loci N Kerimov, JD Hayhurst, K Peikova, JR Manning, P Walter, L Kolberg, ... Nature genetics 53 (9), 1290-1299, 2021 | 280* | 2021 |
Molecular and functional variation in iPSC-derived sensory neurons J Schwartzentruber, S Foskolou, H Kilpinen, J Rodrigues, K Alasoo, ... Nature genetics 50 (1), 54-61, 2018 | 211 | 2018 |
Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription K Alasoo, FO Martinez, C Hale, S Gordon, F Powrie, G Dougan, ... Scientific reports 5 (1), 1-12, 2015 | 103 | 2015 |
Computational biology: deep learning W Jones, K Alasoo, D Fishman, L Parts Emerging Topics in Life Sciences 1 (3), 257-274, 2017 | 101 | 2017 |
Genetic effects on promoter usage are highly context-specific and contribute to complex traits K Alasoo, J Rodrigues, J Danesh, DF Freitag, DS Paul, DJ Gaffney elife 8, e41673, 2019 | 61 | 2019 |
AP-1 takes centre stage in enhancer chromatin dynamics P Madrigal, K Alasoo Trends in cell biology 28 (7), 509-511, 2018 | 59 | 2018 |
Insights from complex trait fine-mapping across diverse populations M Kanai, JC Ulirsch, J Karjalainen, M Kurki, KJ Karczewski, E Fauman, ... medrxiv, 2021.09. 03.21262975, 2021 | 56 | 2021 |
Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2 S Mukhopadhyay, E Heinz, I Porreca, K Alasoo, A Yeung, HT Yang, ... The Journal of Experimental Medicine (JEM) 217 (2), e20180649, 2019 | 56 | 2019 |
Induced pluripotent stem cell derived macrophages as a cellular system to study salmonella and other pathogens C Hale, A Yeung, D Goulding, D Pickard, K Alasoo, F Powrie, G Dougan, ... PloS one 10 (5), e0124307, 2015 | 55 | 2015 |
Co-expression analysis reveals interpretable gene modules controlled by trans-acting genetic variants L Kolberg, N Kerimov, H Peterson, K Alasoo Elife 9, e58705, 2020 | 42 | 2020 |
Molecular quantitative trait loci F Aguet, K Alasoo, YI Li, A Battle, HK Im, SB Montgomery, T Lappalainen Nature Reviews Methods Primers 3 (1), 4, 2023 | 36 | 2023 |
Immune disease variants modulate gene expression in regulatory CD4+ T cells L Bossini-Castillo, DA Glinos, N Kunowska, G Golda, AA Lamikanra, ... Cell genomics 2 (4), 2022 | 26 | 2022 |
wiggleplotr: Make read coverage plots from BigWig files K Alasoo Bioconductor. doi 10, B9, 2017 | 21 | 2017 |
Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 615 (7952), E19-E19, 2023 | 19 | 2023 |
Skin colonization with S. aureus can lead to increased NLRP1 inflammasome activation in patients with atopic dermatitis H Vaher, K Kingo, P Kolberg, M Pook, L Raam, A Laanesoo, A Remm, ... Journal of Investigative Dermatology 143 (7), 1268-1278. e8, 2023 | 10 | 2023 |
Immune disease variants modulate gene expression in regulatory CD4+ T cells and inform drug targets L Bossini-Castillo, DA Glinos, N Kunowska, G Golda, A Lamikanra, ... bioRxiv, 654632, 2019 | 10 | 2019 |