| Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in patients with active inflammatory bowel disease S Schreiber, K Aden, JP Bernardes, C Conrad, F Tran, H Höper, V Volk, ... Gastroenterology 160 (7), 2354-2366. e11, 2021 | 163 | 2021 |
| Hypothalamic inflammation in human obesity is mediated by environmental and genetic factors C Kreutzer, S Peters, DM Schulte, D Fangmann, K Türk, S Wolff, ... Diabetes 66 (9), 2407-2415, 2017 | 149 | 2017 |
| Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells S Rahn, V Zimmermann, F Viol, H Knaack, K Stemmer, L Peters, L Lenk, ... Cancer letters 415, 129-150, 2018 | 127 | 2018 |
| Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data L Lenk, A Alsadeq, DM Schewe Cancer and Metastasis Reviews 39 (1), 173-187, 2020 | 100 | 2020 |
| Targeted microbiome intervention by microencapsulated delayed-release niacin beneficially affects insulin sensitivity in humans D Fangmann, EM Theismann, K Türk, DM Schulte, I Relling, K Hartmann, ... Diabetes Care 41 (3), 398-405, 2018 | 82 | 2018 |
| Epithelial RNase H2 maintains genome integrity and prevents intestinal tumorigenesis in mice K Aden, K Bartsch, J Dahl, MAM Reijns, D Esser, R Sheibani-Tezerji, ... Gastroenterology 156 (1), 145-159. e19, 2019 | 58 | 2019 |
| CD4+ T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells–novel implications of CD4+ T cells … L Goebel, E Grage-Griebenow, A Gorys, O Helm, G Genrich, L Lenk, ... Oncoimmunology 4 (4), e1000083, 2015 | 54 | 2015 |
| Daratumumab eradicates minimal residual disease in a preclinical model of pediatric T-cell acute lymphoblastic leukemia F Vogiatzi, D Winterberg, L Lenk, S Buchmann, G Cario, M Schrappe, ... Blood, The Journal of the American Society of Hematology 134 (8), 713-716, 2019 | 50 | 2019 |
| The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma L Lenk, M Pein, O Will, B Gomez, F Viol, C Hauser, JH Egberts, ... Oncoimmunology 7 (1), e1368603, 2018 | 45 | 2018 |
| IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia A Alsadeq, L Lenk, A Vadakumchery, A Cousins, C Vokuhl, A Khadour, ... Blood, The Journal of the American Society of Hematology 132 (15), 1614-1617, 2018 | 42 | 2018 |
| An Fc-engineered CD19 antibody eradicates MRD in patient-derived MLL-rearranged acute lymphoblastic leukemia xenografts DM Schewe, A Alsadeq, C Sattler, L Lenk, F Vogiatzi, G Cario, S Vieth, ... Blood, The Journal of the American Society of Hematology 130 (13), 1543-1552, 2017 | 40 | 2017 |
| Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells–evidence for a role in hepatocellular carcinoma growth in vivo F Mußbach, H Ungefroren, B Günther, K Katenkamp, P Henklein, ... Molecular Cancer 15 (1), 1-16, 2016 | 35 | 2016 |
| Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells H Knaack, L Lenk, LM Philipp, L Miarka, S Rahn, F Viol, C Hauser, ... Oncotarget 9 (60), 31771, 2018 | 31 | 2018 |
| Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal … A Fabian, S Stegner, L Miarka, J Zimmermann, L Lenk, S Rahn, J Buttlar, ... Cancer Letters 453, 95-106, 2019 | 30 | 2019 |
| Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL K Müller, F Vogiatzi, D Winterberg, T Rösner, L Lenk, L Bastian, ... Blood, 2022 | 28 | 2022 |
| CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia L Lenk, M Carlet, F Vogiatzi, L Spory, D Winterberg, A Cousins, ... Communications biology 4 (1), 1-6, 2021 | 24 | 2021 |
| Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia H Abdelrasoul, A Vadakumchery, M Werner, L Lenk, A Khadour, M Young, ... Nature communications 11 (1), 1-12, 2020 | 20 | 2020 |
| Larotrectinib in TRK fusion–positive pediatric B-cell acute lymphoblastic leukemia DM Schewe, L Lenk, F Vogiatzi, D Winterberg, AV Rademacher, ... Blood advances 3 (22), 3499, 2019 | 20 | 2019 |
| The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells-Nrf2 as … G Genrich, M Kruppa, L Lenk, O Helm, A Broich, S Freitag-Wolf, C Röcken, ... BMC cancer 16 (1), 1-14, 2016 | 20 | 2016 |
| The role of constitutive activation of FMS-related tyrosine kinase-3 and NRas/KRas mutational status in infants with KMT2A-rearranged acute lymphoblastic leukemia H Fedders, A Alsadeq, J Schmäh, F Vogiatzi, M Zimmermann, A Möricke, ... Haematologica 102 (11), e438, 2017 | 16 | 2017 |
