Modeling Rett syndrome with human patient-specific forebrain organoids AR Gomes, TG Fernandes, SH Vaz, TP Silva, EP Bekman, S Xapelli, ... Frontiers in cell and developmental biology 8, 610427, 2020 | 63 | 2020 |
Scalable culture of human induced pluripotent cells on microcarriers under xeno‐free conditions using single‐use vertical‐wheel™ bioreactors CAV Rodrigues, TP Silva, DES Nogueira, TG Fernandes, Y Hashimura, ... Journal of Chemical Technology & Biotechnology 93 (12), 3597-3606, 2018 | 43 | 2018 |
Maturation of human pluripotent stem cell-derived cerebellar neurons in the absence of co-culture TP Silva, E Bekman, TG Fernandes, SH Vaz, CAV Rodrigues, MM Diogo, ... Frontiers in Bioengineering and Biotechnology 8, 70, 2020 | 37 | 2020 |
Design principles for pluripotent stem cell-derived organoid engineering TP Silva, JP Cotovio, E Bekman, M Carmo-Fonseca, J Cabral, ... Stem cells international 2019, 2019 | 35 | 2019 |
Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining TP Silva, TG Fernandes, DES Nogueira, CAV Rodrigues, EP Bekman, ... JoVE (Journal of Visualized Experiments), e61143, 2020 | 34 | 2020 |
Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease CO Miranda, A Marcelo, TP Silva, J Barata, A Vasconcelos-Ferreira, ... Molecular Therapy 26 (9), 2131-2151, 2018 | 27 | 2018 |
Trehalose alleviates the phenotype of Machado–Joseph disease mouse models MM Santana, S Paixão, J Cunha-Santos, TP Silva, A Trevino-Garcia, ... Journal of Translational Medicine 18 (1), 1-17, 2020 | 23 | 2020 |
Transcriptome profiling of human pluripotent stem cell‐derived cerebellar organoids reveals faster commitment under dynamic conditions TP Silva, R Sousa‐Luís, TG Fernandes, EP Bekman, CAV Rodrigues, ... Biotechnology and Bioengineering 118 (7), 2781-2803, 2021 | 21 | 2021 |
Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products B Lee, BS Borys, MS Kallos, CAV Rodrigues, TP Silva, J Cabral Bioengineering 7 (2), 31, 2020 | 21 | 2020 |
Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow−/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia JC Silva, X Han, TP Silva, K Xia, PE Mikael, J Cabral, FC Ferreira, ... Glycoconjugate journal 37 (3), 345-360, 2020 | 17 | 2020 |
Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products B Lee, S Jung, Y Hashimura, M Lee, BS Borys, T Dang, MS Kallos, ... Bioengineering 9 (3), 92, 2022 | 14 | 2022 |
Models to study basic and applied aspects of lysosomal storage disorders Á Gaudioso, TP Silva, MD Ledesma Advanced Drug Delivery Reviews, 114532, 2022 | 8 | 2022 |
Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c. 3612delA TP Silva, CA Pereira, AR Oliveira, AC Raposo, M Arez, JMS Cabral, ... Stem Cell Research 52, 102242, 2021 | 5 | 2021 |
Mesenchymal Stromal Cells’ Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go? I Barros, A Marcelo, TP Silva, J Barata, D Rufino-Ramos, ... Frontiers in Cellular Neuroscience 14, 584277, 2020 | 4 | 2020 |
Bioreactors for Human Pluripotent Stem Cell Expansion and Differentiation CAV Rodrigues, M Branco, DES Nogueira, TP Silva, AR Gomes, ... Bioreactors for Stem Cell Expansion and Differentiation, 25-45, 2018 | 4 | 2018 |
Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation TP Silva, CA Pereira, AC Raposo, AR Oliveira, M Arez, JMS Cabral, ... Stem Cell Research 53, 102364, 2021 | 3 | 2021 |
A Dynamic 3D Aggregate-Based System for the Successful Expansion and Neural Induction of Human Pluripotent Stem Cells CC Miranda, ML Akenhead, TP Silva, MA Derr, MC Vemuri, J Cabral, ... Frontiers in Cellular Neuroscience 16, 70, 2022 | 2 | 2022 |
Reproducing Human Brain Development In Vitro: Generating Cerebellar Neurons for Modelling Cerebellar Ataxias E Bekman, TP Silva, JP Cotovio, RM de Almeida Concepts and Applications of Stem Cell Biology: A Guide for Students, 213-228, 2020 | | 2020 |
Repeated transplantation of mesenchymal stromal cells in Machado-Joseph disease/Spinocerebellar ataxia type-3 mice can sustainably alleviate phenotypic symptoms and … CO Miranda, A Marcelo, TP Silva, J Barata, A Vasconcelos-Ferreira, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 44-44, 2019 | | 2019 |
Repeated mesenchymal stromal cells treatment sustainably alleviates Machado-Joseph disease/spinocerebellar ataxia type-3 CO Miranda, A Marcelo, TP Silva, J Barata, A Vasconcelos-Ferreira, ... HUMAN GENE THERAPY 29 (12), A56-A56, 2018 | | 2018 |