A defined glycosaminoglycan-binding substratum for human pluripotent stem cells JR Klim, L Li, PJ Wrighton, MS Piekarczyk, LL Kiessling Nature methods 7 (12), 989-994, 2010 | 330 | 2010 |
Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification S Musah, PJ Wrighton, Y Zaltsman, X Zhong, S Zorn, MB Parlato, C Hsiao, ... Proceedings of the National Academy of Sciences 111 (38), 13805-13810, 2014 | 190 | 2014 |
Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal S Musah, SA Morin, PJ Wrighton, DB Zwick, S Jin, LL Kiessling ACS nano 6 (11), 10168-10177, 2012 | 174 | 2012 |
YAP regulates hematopoietic stem cell formation in response to the biomechanical forces of blood flow V Lundin, WW Sugden, LN Theodore, PM Sousa, A Han, S Chou, ... Developmental cell 52 (4), 446-460. e5, 2020 | 78 | 2020 |
Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins PJ Wrighton, JR Klim, BA Hernandez, CH Koonce, TJ Kamp, LL Kiessling Proceedings of the National Academy of Sciences 111 (51), 18126-18131, 2014 | 67 | 2014 |
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood O Weeks, GD Bossé, IM Oderberg, S Akle, Y Houvras, PJ Wrighton, ... The Journal of clinical investigation 130 (5), 2252-2269, 2020 | 46 | 2020 |
There is something fishy about liver cancer: zebrafish models of hepatocellular carcinoma PJ Wrighton, IM Oderberg, W Goessling Cellular and molecular gastroenterology and hepatology 8 (3), 347-363, 2019 | 42 | 2019 |
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy PJ Wrighton, A Shwartz, JM Heo, ED Quenzer, KA LaBella, JW Harper, ... Journal of cell science 134 (4), jcs256255, 2021 | 40 | 2021 |
Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair SE DiNapoli, R Martinez-McFaline, CK Gribbin, PJ Wrighton, CA Balgobin, ... Nucleic acids research 48 (7), e38-e38, 2020 | 35 | 2020 |
Small-Molecule-Modified Surfaces Engage Cells through the αvβ3 Integrin JR Klim, AJ Fowler, AH Courtney, PJ Wrighton, RTC Sheridan, ML Wong, ... ACS Chemical Biology 7 (3), 518-525, 2012 | 21 | 2012 |
Forces of change: mechanics underlying formation of functional 3D organ buds PJ Wrighton, LL Kiessling Cell stem cell 16 (5), 453-454, 2015 | 11 | 2015 |
A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization P Luong, Q Li, PF Chen, PJ Wrighton, D Chang, S Dwyer, MT Bayer, ... Molecular biology of the cell 31 (7), 511-519, 2020 | 9 | 2020 |
A total synthetic approach to CRISPR/Cas9 genome editing and homology directed repair SE DiNapoli, R Martinez-McFaline, CK Gribbin, P Wrighton, CA Balgobin, ... BioRxiv, 359984, 2018 | 4 | 2018 |
YAP regulates hematopoietic stem cell formation in response to the biophysical forces of blood flow LN Theodore, V Lundin, PJ Wrighton, AG Cox, P Sousa, W Goessling, ... Blood 130, 1147, 2017 | 2 | 2017 |
Bnip3lb Regulated Mitophagy Maintains the Embryonic Pool of Hematopoietic Stem Cells by Protecting Them from ROS Induced Apoptosis E Meader, PJ Wrighton, I Oderberg, M Leder, M Walcheck, T Long, ... Blood 140 (Supplement 1), 8570-8571, 2022 | 1 | 2022 |
Quantitative intravital imaging reveals in vivo dynamics of physiological-stress induced mitophagy PJ Wrighton, A Shwartz, J Heo, ED Quenzer, KA LaBella, J Wade | 1 | 2020 |
Live imaging defines the dynamics and molecular basis of in vivo mitophagy PJ Wrighton, A Shwartz, JM Heo, ED Quenzer, KA LaBella, JW Harper, ... bioRxiv, 2020.03. 26.010405, 2020 | 1 | 2020 |
Ezh1 inhibits commitment to hemogenic fate and HSPC formation during vertebrate development R Soto, LT Vo, M Hachimi, JM Frame, PJ Wrighton, W Goessling, ... Blood 134, 3710, 2019 | 1 | 2019 |
Investigating the role of EZH1 in developmental hematopoiesis R Soto, P Wrighton, G Daley, W Goessling, T North Experimental Hematology 76, S86, 2019 | 1 | 2019 |
3017–MECHANISMS OF FLOW-DRIVEN TRANSCRIPTIONAL CONTROL OF HEMATOPOIETIC STEM CELL DEVELOPMENT VIA YAP/TAZ REGULATION W Sugden, P Wrighton, Z LeBlanc, MG di Tillio, M Najia, E Quenzer, ... Experimental Hematology 111, S53, 2022 | | 2022 |