| Lipopolysaccharide primes the NALP3 inflammasome by inhibiting its ubiquitination and degradation mediated by the SCFFBXL2 E3 ligase SH Han, TB Lear, JA Jerome, S Rajbhandari, CA Snavely, DL Gulick, ... Journal of Biological Chemistry 290 (29), 18124-18133, 2015 | 179 | 2015 |
| F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation J Zhao, J Wei, RK Mialki, DF Mallampalli, BB Chen, T Coon, C Zou, ... Nature immunology 13 (7), 651-658, 2012 | 166 | 2012 |
| Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia NB Ray, L Durairaj, BB Chen, BJ McVerry, AJ Ryan, M Donahoe, ... Nature medicine 16 (10), 1120-1127, 2010 | 147 | 2010 |
| A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation BB Chen, TA Coon, JR Glasser, BJ McVerry, J Zhao, Y Zhao, C Zou, ... Nature immunology 14 (5), 470-479, 2013 | 136 | 2013 |
| The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia K Chakraborty, M Raundhal, BB Chen, C Morse, YY Tyurina, A Khare, ... Nature Communications 8 (1), 13944, 2017 | 111 | 2017 |
| Acyl-CoA: lysophosphatidylcholine acyltransferase I (Lpcat1) catalyzes histone protein O-palmitoylation to regulate mRNA synthesis C Zou, BM Ellis, RM Smith, BB Chen, Y Zhao, RK Mallampalli Journal of Biological Chemistry 286 (32), 28019-28025, 2011 | 91 | 2011 |
| F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation BB Chen, JR Glasser, TA Coon, C Zou, HL Miller, M Fenton, JF McDyer, ... Blood, The Journal of the American Society of Hematology 119 (13), 3132-3141, 2012 | 90 | 2012 |
| Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation … DJ Ranayhossaini, AI Rodriguez, S Sahoo, BB Chen, RK Mallampalli, ... Journal of Biological Chemistry 288 (51), 36437-36450, 2013 | 86 | 2013 |
| Host-response subphenotypes offer prognostic enrichment in patients with or at risk for acute respiratory distress syndrome GD Kitsios, L Yang, DV Manatakis, M Nouraie, J Evankovich, W Bain, ... Critical care medicine 47 (12), 1724-1734, 2019 | 84 | 2019 |
| SCF E3 ligase F-box protein complex SCFFBXL19 regulates cell migration by mediating Rac1 ubiquitination and degradation J Zhao, RK Mialki, J Wei, TA Coon, C Zou, BB Chen, RK Mallampalli, ... The FASEB Journal 27 (7), 2611, 2013 | 82 | 2013 |
| 14-3-3 binding and phosphorylation of neuroglobin during hypoxia modulate six-to-five heme pocket coordination and rate of nitrite reduction to nitric oxide T Jayaraman, J Tejero, BB Chen, AB Blood, S Frizzell, C Shapiro, M Tiso, ... Journal of Biological Chemistry 286 (49), 42679-42689, 2011 | 80 | 2011 |
| F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest BB Chen, JR Glasser, TA Coon, RK Mallampalli Oncogene 31 (20), 2566-2579, 2012 | 77 | 2012 |
| F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7 Y Liu, T Lear, Y Zhao, J Zhao, C Zou, BB Chen, RK Mallampalli Cell death & disease 6 (2), e1630-e1630, 2015 | 75 | 2015 |
| Masking of a nuclear signal motif by monoubiquitination leads to mislocalization and degradation of the regulatory enzyme cytidylyltransferase BB Chen, RK Mallampalli Molecular and cellular biology, 2009 | 70 | 2009 |
| The proapoptotic F-box protein Fbxl7 regulates mitochondrial function by mediating the ubiquitylation and proteasomal degradation of survivin Y Liu, T Lear, O Iannone, S Shiva, C Corey, S Rajbhandari, J Jerome, ... Journal of Biological Chemistry 290 (19), 11843-11852, 2015 | 67 | 2015 |
| Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest TA Coon, JR Glasser, RK Mallampalli, BB Chen Cell cycle 11 (4), 721-729, 2012 | 66 | 2012 |
| Targeting F box protein Fbxo3 to control cytokine-driven inflammation RK Mallampalli, TA Coon, JR Glasser, C Wang, SR Dunn, ... The Journal of Immunology 191 (10), 5247-5255, 2013 | 62 | 2013 |
| Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis BB Chen, JR Glasser, TA Coon, RK Mallampalli Cell death & disease 4 (8), e759-e759, 2013 | 60 | 2013 |
| A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry Y Chen, TB Lear, JW Evankovich, MB Larsen, B Lin, I Alfaras, ... Nature communications 12 (1), 3907, 2021 | 59 | 2021 |
| Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity JS Bednash, N Weathington, J Londino, M Rojas, DL Gulick, R Fort, ... Nature communications 8 (1), 15203, 2017 | 58 | 2017 |
